13-825 Search Results


mef 2b  (R&D Systems)
92
R&D Systems mef 2b
Mef 2b, supplied by R&D Systems, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mef 2b - by Bioz Stars, 2026-04
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hdac8 flag  (Addgene inc)
93
Addgene inc hdac8 flag
WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or <t>HDAC8</t> overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).
Hdac8 Flag, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hdac8 flag/product/Addgene inc
Average 93 stars, based on 1 article reviews
hdac8 flag - by Bioz Stars, 2026-04
93/100 stars
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remlan m-1 13825.02  (SERVA Electrophoresis)
90
SERVA Electrophoresis remlan m-1 13825.02
WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or <t>HDAC8</t> overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).
Remlan M 1 13825.02, supplied by SERVA Electrophoresis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/remlan m-1 13825.02/product/SERVA Electrophoresis
Average 90 stars, based on 1 article reviews
remlan m-1 13825.02 - by Bioz Stars, 2026-04
90/100 stars
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isopropanol cat#13825  (Fisher Scientific)
90
Fisher Scientific isopropanol cat#13825
WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or <t>HDAC8</t> overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).
Isopropanol Cat#13825, supplied by Fisher Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/isopropanol cat#13825/product/Fisher Scientific
Average 90 stars, based on 1 article reviews
isopropanol cat#13825 - by Bioz Stars, 2026-04
90/100 stars
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iso-propanol qualigens #13825  (Qualigens Fine Chemicals Pvt Ltd)
90
Qualigens Fine Chemicals Pvt Ltd iso-propanol qualigens #13825
WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or <t>HDAC8</t> overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).
Iso Propanol Qualigens #13825, supplied by Qualigens Fine Chemicals Pvt Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/iso-propanol qualigens #13825/product/Qualigens Fine Chemicals Pvt Ltd
Average 90 stars, based on 1 article reviews
iso-propanol qualigens #13825 - by Bioz Stars, 2026-04
90/100 stars
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renlam® m-1 (serva 13825)  (SERVA Electrophoresis)
90
SERVA Electrophoresis renlam® m-1 (serva 13825)
WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or <t>HDAC8</t> overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).
Renlam® M 1 (Serva 13825), supplied by SERVA Electrophoresis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/renlam® m-1 (serva 13825)/product/SERVA Electrophoresis
Average 90 stars, based on 1 article reviews
renlam® m-1 (serva 13825) - by Bioz Stars, 2026-04
90/100 stars
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v. splendidus lp1 ncimb 13825  (NCIMB Ltd)
90
NCIMB Ltd v. splendidus lp1 ncimb 13825
WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or <t>HDAC8</t> overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).
V. Splendidus Lp1 Ncimb 13825, supplied by NCIMB Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/v. splendidus lp1 ncimb 13825/product/NCIMB Ltd
Average 90 stars, based on 1 article reviews
v. splendidus lp1 ncimb 13825 - by Bioz Stars, 2026-04
90/100 stars
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brain heart infusion agar bhi 1.13825  (Merck KGaA)
90
Merck KGaA brain heart infusion agar bhi 1.13825
WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or <t>HDAC8</t> overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).
Brain Heart Infusion Agar Bhi 1.13825, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/brain heart infusion agar bhi 1.13825/product/Merck KGaA
Average 90 stars, based on 1 article reviews
brain heart infusion agar bhi 1.13825 - by Bioz Stars, 2026-04
90/100 stars
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fermentor p. methanolica sc 13825  (Dow Corning)
90
Dow Corning fermentor p. methanolica sc 13825
WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or <t>HDAC8</t> overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).
Fermentor P. Methanolica Sc 13825, supplied by Dow Corning, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/fermentor p. methanolica sc 13825/product/Dow Corning
Average 90 stars, based on 1 article reviews
fermentor p. methanolica sc 13825 - by Bioz Stars, 2026-04
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Image Search Results


WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or HDAC8 overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).

Journal: Scientific Reports

Article Title: The hydroxamate based HDAC inhibitor WMJ-J-09 induces colorectal cancer cell death by targeting tubulin and downregulating survivin

doi: 10.1038/s41598-025-04714-w

Figure Lengend Snippet: WMJ-J-09 disrupted microtubule assembly through HDAC inhibition. ( A ) Microtubule formation in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle, detected by confocal immunofluorescence analysis with β-tubulin-staining images in the upper panel, DAPI-staining images in the middle panel, and merged images in the bottom panel. ( B ) Immunoblotting result of polymerized tubulin in HCT116 cells treated with colchicine, paclitaxel, WMJ-J-09, or vehicle ( C , D ) Immunoblot result of α-tubulin acetylation induced by WMJ-J-09 in either a concentration-dependent ( C ) or time-dependent manner ( D ). ( E ) Immunoblot result of α-tubulin acetylation in WMJ-J-09-treated HCT116 cells with HDAC6 or HDAC8 overexpression. Each band intensity was quantified, and the total α-tubulin level normalized the fold changes of α-tubulin acetylation. Error bars, mean ± S.E.M. (shown only for independent replicate experiments with n ≥ 5).

Article Snippet: HDAC8 Flag was a gift from Eric Verdin (Addgene plasmid # 13825; http://n2t.net/addgene:13825 ; RRID:Addgene_13825) .

Techniques: Inhibition, Immunofluorescence, Staining, Western Blot, Concentration Assay, Over Expression