93
|
Selleck Chemicals
wt161 ![]() Wt161, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/wt161/pmc08202734-107-0-2?v=Selleck+Chemicals Average 93 stars, based on 1 article reviews
wt161 - by Bioz Stars,
2026-08
93/100 stars
|
Buy from Supplier |
90
|
Acetylon Inc
wt-161 ![]() Wt 161, supplied by Acetylon Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/wt161/us11059815-175-0-7?v=Acetylon+Inc Average 90 stars, based on 1 article reviews
wt-161 - by Bioz Stars,
2026-08
90/100 stars
|
Buy from Supplier |
N/A
|
InformationWT161 is a potent, selective, and bioavailableHDAC6inhibitor withIC50 valuesof 0.4 nM, 8.35 nM and 15.4 nM for HDAC6, HDAC1 and HDAC2, respectively; shown to have >100-fold selectivity over other HDACs. WT161 inducesapoptosis.TargetsHDAC6 (Cell-free assay); HDAC1
|
Buy from Supplier |
N/A
|
WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM. WT-161 also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2).
|
Buy from Supplier |
N/A
|
WT161(Cat No.:R066903)is a potent, selective inhibitor of histone deacetylase 6 (HDAC6), an enzyme involved in regulating protein degradation, cell motility, and immune responses. By inhibiting HDAC6, WT161 disrupts the deacetylation of proteins such as tubulin
|
Buy from Supplier |
N/A
|
WT-161 is a potent and specific HDAC6 inhibitor (IC50= 0.40 nM). Consistent with WT-161 mediated hyperacetylation and inhibition of hsp90 chaperone function, treatment with WT-161 increased the intracellular levels of polyubiuitylated proteins in the cultured
|
Buy from Supplier |
N/A
|
WT161 is a potent inhibitor of HDAC6 with an IC value of 0 40 nM It is selective for HDAC6 over HDAC3 IC 51 61 nM and induces α tubulin acetylation an HDAC6 dependent process
|
Buy from Supplier |
Image Search Results
Journal: Cell Stem Cell
Article Title: Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids
doi: 10.1016/j.stem.2021.03.022
Figure Lengend Snippet:
Article Snippet:
Techniques: Activity Assay, Colorimetric Assay, Staining, Plasmid Preparation, Recombinant, Software, Cell Recovery