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Image Search Results
Journal: Molecular Medicine Reports
Article Title: SIRT3 regulates bronchial epithelium apoptosis and aggravates airway inflammation in asthma
doi: 10.3892/mmr.2022.12660
Figure Lengend Snippet: Upregulation of SIRT3 reduced increased inflammation of BALF in asthmatic mice. (A) The number of cells in BALF as determined by Wright's Giemsa staining. (B) The expression of cytokines (TNF-α, IL-4, IL-5 and IL-13) mRNA in cells of BALF determined by reverse transcription-quantitative PCR. (C) The secretion levels of cytokines (TNF-α, IL-4, IL-5 and IL-13) in BALF determined with ELISA assay. DEX treatment was used as the positive control. There were seven mice in each group, the data were shown as mean ± SD and the P-value was calculated by calculated by post-hoc comparisons. ns, P>0.05, *P>0.05, **P<0.01 and ***P<0.001 vs. Asthma group. SIRT3, sirtuin 3; BALF, bronchoalveolar lavage fluid; DEX, dexamethasone.
Article Snippet:
Techniques: Staining, Expressing, Reverse Transcription, Real-time Polymerase Chain Reaction, Enzyme-linked Immunosorbent Assay, Positive Control