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MedChemExpress
v 9302 V 9302, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/v9302/V-9302/10__3390_slash_cancers18071068-131-23-24 Average 94 stars, based on 1 article reviews
v 9302 - by Bioz Stars,
2026-10
94/100 stars
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V-9302 hydrochloride(CAT: L004733) bearing a unique identifier, plays a pivotal role in pharmaceutical and organic chemistry. Its specific structure suggests its potential as a modulator of specific cellular pathways or targets. In pharmaceutical research, it
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Selleck Chemicals
v 9302 V 9302, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/v9302/V-9302/pmc08486573-90-6-16 Average 93 stars, based on 1 article reviews
v 9302 - by Bioz Stars,
2026-10
93/100 stars
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MedChemExpress
v9302 hydrochloride ![]() V9302 Hydrochloride, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/v9302/V-9302+hydrochloride/pm37420266-39-0-5 Average 93 stars, based on 1 article reviews
v9302 hydrochloride - by Bioz Stars,
2026-10
93/100 stars
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Sifam Pharmaceuticals
fh-v9302-sifam-nds-dil ![]() Fh V9302 Sifam Nds Dil, supplied by Sifam Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/v9302/fh+v9302+sifam+nds+dil/pmc10329298-133-9-22 Average 90 stars, based on 1 article reviews
fh-v9302-sifam-nds-dil - by Bioz Stars,
2026-10
90/100 stars
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Topscience Co Ltd
v9302 ![]() V9302, supplied by Topscience Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/v9302/v9302/pm40258477-29-0-4 Average 90 stars, based on 1 article reviews
v9302 - by Bioz Stars,
2026-10
90/100 stars
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description:V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells
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V-9302(CAT: I019215) is a potent, selective, and competitive antagonist of transmembrane glutamine flux that specifically targets the amino acid transporter ASCT2 (SLC1A5) without affecting ASCT1. It inhibits ASCT2-mediated glutamine uptake with an IC₅₀ of 9.6
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Image Search Results
Journal: Journal of nanobiotechnology
Article Title: CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
doi: 10.1186/s12951-023-01979-z
Figure Lengend Snippet: Fig. 1 Schematic diagram illustrating antitumor effects by combining of UTMD and FH-V9302-siGLUL-NDs to cancer cells and CAFs
Article Snippet:
Techniques:
Journal: Journal of nanobiotechnology
Article Title: CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
doi: 10.1186/s12951-023-01979-z
Figure Lengend Snippet: Fig. 2 Preparation and characterization of the nanodroplets. (A) Preparation of the nanodroplets. (B) Fluorescence microscope diagram of FH-V9302- siGLUL-NDs. Scale bars: 10 μm. (C) Transmission electron microscopy (TEM) of FH-V9302-siGLUL-NDs at a volume ratio of 1:20 ratio (siGLUL: nanodrop lets). Scale bars: 200 nm. (D) FH-V9302-siGLUL-NDs size distribution. (E) Drug release of FH-V9302-siGLUL-NDs with or without ultrasound stimulation (0.5 W/cm2, 60 s, 1.0 MHz). (F) US imaging in vitro. (G) US imaging in vivo. The red circle indicates the site of the tumor. All statistical data are expressed as means ± SD (n = 3)
Article Snippet:
Techniques: Fluorescence, Microscopy, Transmission Assay, Electron Microscopy, Imaging, In Vitro, In Vivo
Journal: Journal of nanobiotechnology
Article Title: CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
doi: 10.1186/s12951-023-01979-z
Figure Lengend Snippet: Fig. 3 Characterization of FH-V9302-siGLUL-NDs and gene silencing efficiency. (A) Agarose gel electrophoresis retardation assay of FH-V9302-NDs with siGLUL in different volume ratios. (B) ζ potential changes of siGLUL with FH-V9302-NDs at different volume ratios (n = 3). (C) ζ potential of FH-V9302-NDs and FH-V9302-siGLUL-NDs (n = 3). (D) Western blot analysis of B16F10 and CAFs cells with different treatment knockdown GLUL levels. (E) Western blot analysis of different nanodroplets loading siGLUL knockdown GLUL levels. (F&G) Quantitative analysis of GLUL expression in B16F10(F) and CAFs(G) cells under different treatments. (H&I) Quantitative analysis of GLUL expression in B16F10 (H) and CAFs (I) cells treated with different nanodroplets loading siGLUL. *p < 0.05, **p < 0.01, ****p < 0.0001 (ANOVA test). All statistical data are expressed as means ± SD (n = 3)
Article Snippet:
Techniques: Agarose Gel Electrophoresis, Western Blot, Knockdown, Expressing
Journal: Journal of nanobiotechnology
Article Title: CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
doi: 10.1186/s12951-023-01979-z
Figure Lengend Snippet: Fig. 5 Safety evaluation. (A) Hemolytic behavior of Free V9302. (B) Hemolytic behavior of FH-V9302-siGLUL-NDs. (C) Hemolytic behavior of FH-NDs. (D) Statistics of hemolysis of Free V9302. (E) Statistics of hemolysis of FH-V9302-siGLUL-NDs. (F) Statistics of hemolysis of FH-NDs. (G) Agarose gel electro phoresis retardation assay of serum stability of naked siGLUL (a) and FH-V9302-siGLUL-NDs (b) in 50% fetal bovine serum. (H) Cytotoxicity of FH-NDs at different concentration in CAFs. (I) Cytotoxicity of FH-NDs at different concentration in B16F10. (J) Body weight changes of mice between treatments (n = 5). (K) H&E staining of major organs after intravenous injection of FH-V9302-siGLUL-NDs. Scale bar: 100 μm. *p < 0.05 (ANOVA test). All statistical data are expressed as means ± SD (n = 3)
Article Snippet:
Techniques: Agarose Gel Electrophoresis, Concentration Assay, Staining, Injection
Journal: Journal of nanobiotechnology
Article Title: CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
doi: 10.1186/s12951-023-01979-z
Figure Lengend Snippet: Fig. 10 In vivo antitumor efficacy and reprogramming of TME. (A) Photographs of tumor formed by B16F10 and CAFs after four treatments. (B) Changes of tumor volume during the treatment (n = 5) **p < 0.001(t-test). (C) Weight of tumors formed by B16F10 and CAFs after four treatments (n = 5). (D) H&E staining. Scale bar: 200 μm. (E) Ki67 staining. Scale bar: 200 μm. (F) Tunel staining. Scale bar: 200 μm. (G) Masson trichrome staining. Scale bar: 200 μm. (H) IHC staining of α-SMA. Scale bar: 200 μm. (I) IHC staining of GLUL. Scale bar: 200 μm. (J) Ki67 index analysis (n = 3). (K) Quantitative analysis of Tunel positive cells (n = 3). (L) Analysis of positive area of Masson (n = 3). (M) Quantitative analysis of α-SMA (n = 3). (N) Analysis of positive area of GLUL (n = 3). * p < 0.05, ** p < 0.01, and *** p < 0.001 (ANOVA test). All statistical data are expressed as means ± SD (n = 5). G1, Control; G2, FH-siGLUL-NDs; G3, FH-V9302- NDs; G4, Free V9302; G5, FH-V9302-siGLUL-NDs; G6, V9302-siGLUL-NDs + US; and G7, FH-V9302-siGLUL-NDs + US
Article Snippet:
Techniques: In Vivo, Staining, TUNEL Assay, Immunohistochemistry, Control