Journal: Translational Vision Science & Technology

Article Title: IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space

doi: 10.1167/tvst.13.10.14

Figure Lengend Snippet: Representative ultrasound biomicroscopy images of the SCS after hydrogel injection. ( A ) Hypertensive and ( B ) normotensive eyes are shown after injection with crosslinked hydrogel or sham injection of Hanks’ Balanced Salt Solution. All images are in the same orientation (C, cornea; I, iris; CB, ciliary body; Ch, choroid; H, hydrogel; S, sclera). The dotted yellow line approximately outlines the hydrogel in the SCS; these images were used to determine EWT. Each injection type (sham or hydrogel) across time points is from the same eye. Images are representative of three sham eyes and six hydrogel eyes for hypertensive animals and two sham eyes and seven hydrogel eyes for normotensive animals.

Article Snippet: The extent of SCS expansion was determined by analysis of images of the limbal region, acquired by ultrasound biomicroscopy (UBM Plus; Accutome, Malvern, PA, USA) with a sterile probe cover (ClearScan; Eye-Surgical-Instruments, Plymouth, MN, USA).

Techniques: Injection

Journal: OTA International

Article Title: The use of xenogenic dermal matrices in the context of open extremity wounds: where and when to consider?

doi: 10.1097/OI9.0000000000000237

Figure Lengend Snippet: A, AP and lateral views of initial injury treated with (B) serial debridements and antibiotic bead placement with external fixation. Definitive fixation was performed with (C) distraction osteogenesis in a circular external fixator for several months followed by intramedullary nail placement across the docking site. After circular frame was removed, (D) a chronic wound with exposed bone was present on the anterior tibia. Aggressive debridement was performed initially, and bone vascularity was noted to be poor. Porcine urinary bladder matrix (UBM) powder was first placed followed by layered UBM and left in place for 3 weeks, resulting in (E) a healthy layer of granulation tissue filling the wound bed. After gentle irrigation and debridement, (F) a split thickness skin graft was applied. G, The anterior tibia defect was completely healed without complications of infection or need for further ADM application.

Article Snippet: Given the wound's location, chronicity, exposed bone, and limited vascularity, the authors applied powered UBM (Acell Micromatrix) followed by layered UBM (Acell Cytal) at the time of initial debridement.

Techniques: Gentle, Infection