Journal: Translational Vision Science & Technology

Article Title: IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space

doi: 10.1167/tvst.13.10.14

Figure Lengend Snippet: Representative ultrasound biomicroscopy images of the SCS after hydrogel injection. ( A ) Hypertensive and ( B ) normotensive eyes are shown after injection with crosslinked hydrogel or sham injection of Hanks’ Balanced Salt Solution. All images are in the same orientation (C, cornea; I, iris; CB, ciliary body; Ch, choroid; H, hydrogel; S, sclera). The dotted yellow line approximately outlines the hydrogel in the SCS; these images were used to determine EWT. Each injection type (sham or hydrogel) across time points is from the same eye. Images are representative of three sham eyes and six hydrogel eyes for hypertensive animals and two sham eyes and seven hydrogel eyes for normotensive animals.

Article Snippet: The extent of SCS expansion was determined by analysis of images of the limbal region, acquired by ultrasound biomicroscopy (UBM Plus; Accutome, Malvern, PA, USA) with a sterile probe cover (ClearScan; Eye-Surgical-Instruments, Plymouth, MN, USA).

Techniques: Injection