triparanol Search Results


triparanol(mer-29)  (MuseChem Chemicals)
N/A
Triparanol (MER-29) is an inhibitor of 24-dehydrocholesterol reductase (DHCR24), an enzyme involved in cholesterol biosynthesis. It exhibits antitumor properties, such as decreasing proliferation and inducing apoptosis in various cancer cell lines, while also reducing Hedgehog
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triparanol  (1PlusChem LLC)
N/A
Triparanol
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triparanol  (Santa Cruz Biotechnology)
91
Santa Cruz Biotechnology triparanol
SOX9 modulates cholesterol biosynthesis via DHCR24. (A) Total and free cholesterol levels were measured in DLBCL cells with high (Karpas-422 and DB) or low (OCI-LY1 and SUDHL8) levels of SOX9. A total of 1 × 10 6 cells were used for each measurement. (B-D) Total and free cholesterol levels were measured in SOX9 − Karpas-422 cells and DB cells and in SOX9-overexpressing OCI-LY1 cells. The level of cholesterol ester was calculated: total cholesterol − free cholesterol content. (E) Immunoblot assay and densitometry quantitation of DHCR24 protein in SOX9 − Karpas-422 and DB cells. (F) Karpas-422 or DB cells were treated with <t>triparanol</t> for 48 hours or left untreated before they were subjected to cholesterol content measurement. (A-D, F) Data represent the mean ± SD of technical triplicates. * P < .05; ** P < .01; *** P < .001.
Triparanol, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/triparanol/Triparanol/pmc08740888-40-1-13
Average 91 stars, based on 1 article reviews
triparanol - by Bioz Stars, 2026-10
91/100 stars
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triparanol  (Marion Merrell DOW Inc)
90
Marion Merrell DOW Inc triparanol
SOX9 modulates cholesterol biosynthesis via DHCR24. (A) Total and free cholesterol levels were measured in DLBCL cells with high (Karpas-422 and DB) or low (OCI-LY1 and SUDHL8) levels of SOX9. A total of 1 × 10 6 cells were used for each measurement. (B-D) Total and free cholesterol levels were measured in SOX9 − Karpas-422 cells and DB cells and in SOX9-overexpressing OCI-LY1 cells. The level of cholesterol ester was calculated: total cholesterol − free cholesterol content. (E) Immunoblot assay and densitometry quantitation of DHCR24 protein in SOX9 − Karpas-422 and DB cells. (F) Karpas-422 or DB cells were treated with <t>triparanol</t> for 48 hours or left untreated before they were subjected to cholesterol content measurement. (A-D, F) Data represent the mean ± SD of technical triplicates. * P < .05; ** P < .01; *** P < .001.
Triparanol, supplied by Marion Merrell DOW Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/triparanol/triparanol/pm07559634-58-0-8
Average 90 stars, based on 1 article reviews
triparanol - by Bioz Stars, 2026-10
90/100 stars
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triparanol  (Martin Dunitz)
90
Martin Dunitz triparanol
SOX9 modulates cholesterol biosynthesis via DHCR24. (A) Total and free cholesterol levels were measured in DLBCL cells with high (Karpas-422 and DB) or low (OCI-LY1 and SUDHL8) levels of SOX9. A total of 1 × 10 6 cells were used for each measurement. (B-D) Total and free cholesterol levels were measured in SOX9 − Karpas-422 cells and DB cells and in SOX9-overexpressing OCI-LY1 cells. The level of cholesterol ester was calculated: total cholesterol − free cholesterol content. (E) Immunoblot assay and densitometry quantitation of DHCR24 protein in SOX9 − Karpas-422 and DB cells. (F) Karpas-422 or DB cells were treated with <t>triparanol</t> for 48 hours or left untreated before they were subjected to cholesterol content measurement. (A-D, F) Data represent the mean ± SD of technical triplicates. * P < .05; ** P < .01; *** P < .001.
Triparanol, supplied by Martin Dunitz, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/triparanol/triparanol/pm17209661-156-5-1
Average 90 stars, based on 1 article reviews
triparanol - by Bioz Stars, 2026-10
90/100 stars
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triparanol mdl 5052  (Marion Merrell DOW Inc)
90
Marion Merrell DOW Inc triparanol mdl 5052
SOX9 modulates cholesterol biosynthesis via DHCR24. (A) Total and free cholesterol levels were measured in DLBCL cells with high (Karpas-422 and DB) or low (OCI-LY1 and SUDHL8) levels of SOX9. A total of 1 × 10 6 cells were used for each measurement. (B-D) Total and free cholesterol levels were measured in SOX9 − Karpas-422 cells and DB cells and in SOX9-overexpressing OCI-LY1 cells. The level of cholesterol ester was calculated: total cholesterol − free cholesterol content. (E) Immunoblot assay and densitometry quantitation of DHCR24 protein in SOX9 − Karpas-422 and DB cells. (F) Karpas-422 or DB cells were treated with <t>triparanol</t> for 48 hours or left untreated before they were subjected to cholesterol content measurement. (A-D, F) Data represent the mean ± SD of technical triplicates. * P < .05; ** P < .01; *** P < .001.
Triparanol Mdl 5052, supplied by Marion Merrell DOW Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/triparanol/triparanol+mdl+5052/A3cnAuJWszUGUeHoyiVf9uvyW0Y8SExggRkmBZUsG55I6aRuv9wtU4Xk848eUzxRV9UMCUK8PefXoCTnkZ-27-2-13
Average 90 stars, based on 1 article reviews
triparanol mdl 5052 - by Bioz Stars, 2026-10
90/100 stars
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triparanol  (Toronto Research Chemicals)
N/A
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triparanol  (BOC Sciences)
N/A
Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor with Ki value of 0.523 µM. It can be used as an antilipemic agent. It also exhibits anticancer activity that suppresses proliferation and induces apoptosis in many
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triparanol  (Cayman Chemical)
N/A
Triparanol is a 24 dehydro cholesterol reductase DHCR24 inhibitor K 0 523 µM which is an enzyme involved in the biosynthesis of cholesterol It has antitumor properties such as decreasing proliferation and inducing apoptosis in
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triparanol  (Biosynth Carbosynth)
N/A
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Image Search Results


SOX9 modulates cholesterol biosynthesis via DHCR24. (A) Total and free cholesterol levels were measured in DLBCL cells with high (Karpas-422 and DB) or low (OCI-LY1 and SUDHL8) levels of SOX9. A total of 1 × 10 6 cells were used for each measurement. (B-D) Total and free cholesterol levels were measured in SOX9 − Karpas-422 cells and DB cells and in SOX9-overexpressing OCI-LY1 cells. The level of cholesterol ester was calculated: total cholesterol − free cholesterol content. (E) Immunoblot assay and densitometry quantitation of DHCR24 protein in SOX9 − Karpas-422 and DB cells. (F) Karpas-422 or DB cells were treated with triparanol for 48 hours or left untreated before they were subjected to cholesterol content measurement. (A-D, F) Data represent the mean ± SD of technical triplicates. * P < .05; ** P < .01; *** P < .001.

Journal: Blood

Article Title: Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2 + diffuse large B-cell lymphomas

doi: 10.1182/blood.2021012327

Figure Lengend Snippet: SOX9 modulates cholesterol biosynthesis via DHCR24. (A) Total and free cholesterol levels were measured in DLBCL cells with high (Karpas-422 and DB) or low (OCI-LY1 and SUDHL8) levels of SOX9. A total of 1 × 10 6 cells were used for each measurement. (B-D) Total and free cholesterol levels were measured in SOX9 − Karpas-422 cells and DB cells and in SOX9-overexpressing OCI-LY1 cells. The level of cholesterol ester was calculated: total cholesterol − free cholesterol content. (E) Immunoblot assay and densitometry quantitation of DHCR24 protein in SOX9 − Karpas-422 and DB cells. (F) Karpas-422 or DB cells were treated with triparanol for 48 hours or left untreated before they were subjected to cholesterol content measurement. (A-D, F) Data represent the mean ± SD of technical triplicates. * P < .05; ** P < .01; *** P < .001.

Article Snippet: Simvastatin, triparanol, and JQ1 were purchased from Med Chem Express (Monmouth Junction, NJ), Santa Cruz Biotechnology (Dallas, TX), and Selleckchem (Houston, TX), respectively.

Techniques: Western Blot, Quantitation Assay

SOX9 modulates cholesterol biosynthesis via DHCR24. (A) Total and free cholesterol levels were measured in DLBCL cells with high (Karpas-422 and DB) or low (OCI-LY1 and SUDHL8) levels of SOX9. A total of 1 × 10 6 cells were used for each measurement. (B-D) Total and free cholesterol levels were measured in SOX9 − Karpas-422 cells and DB cells and in SOX9-overexpressing OCI-LY1 cells. The level of cholesterol ester was calculated: total cholesterol − free cholesterol content. (E) Immunoblot assay and densitometry quantitation of DHCR24 protein in SOX9 − Karpas-422 and DB cells. (F) Karpas-422 or DB cells were treated with triparanol for 48 hours or left untreated before they were subjected to cholesterol content measurement. (A-D, F) Data represent the mean ± SD of technical triplicates. * P < .05; ** P < .01; *** P < .001; **** P < 0.0005.

Journal: Blood

Article Title: Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2 + diffuse large B-cell lymphomas

doi: 10.1182/blood.2021012327

Figure Lengend Snippet: SOX9 modulates cholesterol biosynthesis via DHCR24. (A) Total and free cholesterol levels were measured in DLBCL cells with high (Karpas-422 and DB) or low (OCI-LY1 and SUDHL8) levels of SOX9. A total of 1 × 10 6 cells were used for each measurement. (B-D) Total and free cholesterol levels were measured in SOX9 − Karpas-422 cells and DB cells and in SOX9-overexpressing OCI-LY1 cells. The level of cholesterol ester was calculated: total cholesterol − free cholesterol content. (E) Immunoblot assay and densitometry quantitation of DHCR24 protein in SOX9 − Karpas-422 and DB cells. (F) Karpas-422 or DB cells were treated with triparanol for 48 hours or left untreated before they were subjected to cholesterol content measurement. (A-D, F) Data represent the mean ± SD of technical triplicates. * P < .05; ** P < .01; *** P < .001; **** P < 0.0005.

Article Snippet: Simvastatin, triparanol, and JQ1 were purchased from Med Chem Express (Monmouth Junction, NJ), Santa Cruz Biotechnology (Dallas, TX), and Selleckchem (Houston, TX), respectively.

Techniques: Western Blot, Quantitation Assay