tp449 Search Results


tp449  (Enamine Ltd)
94
Enamine Ltd tp449
Correlation of sitagliptin (STG), <t>TP449,</t> TP233, and TP192 with iron(II) (Fe²⁺), nitrate (NO₃⁻), and sulfate (SO₄²⁻) concentrations in pore water samples collected from the River Erpe at Site A (muddy). Dashed lines represent trend lines based on locally weighted scatterplot smoothing (LOWESS) with a smoothing factor of 0.7. Spearman’s rank correlation coefficients (rs) and corresponding p-values are shown in each subplot.
Tp449, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Correlation of sitagliptin (STG), TP449, TP233, and TP192 with iron(II) (Fe²⁺), nitrate (NO₃⁻), and sulfate (SO₄²⁻) concentrations in pore water samples collected from the River Erpe at Site A (muddy). Dashed lines represent trend lines based on locally weighted scatterplot smoothing (LOWESS) with a smoothing factor of 0.7. Spearman’s rank correlation coefficients (rs) and corresponding p-values are shown in each subplot.

Journal: bioRxiv

Article Title: Sequential exposure to anoxic/oxic conditions leads to biotransformation and detoxification of sitagliptin in urban hyporheic zones

doi: 10.1101/2025.06.03.657625

Figure Lengend Snippet: Correlation of sitagliptin (STG), TP449, TP233, and TP192 with iron(II) (Fe²⁺), nitrate (NO₃⁻), and sulfate (SO₄²⁻) concentrations in pore water samples collected from the River Erpe at Site A (muddy). Dashed lines represent trend lines based on locally weighted scatterplot smoothing (LOWESS) with a smoothing factor of 0.7. Spearman’s rank correlation coefficients (rs) and corresponding p-values are shown in each subplot.

Article Snippet: TP449 (N-acetyl sitagliptin) was purchased from Enamine (Frankfurt (Main), Germany).

Techniques:

Relative cytotoxicity of sitagliptin (STG), its transformation products (TPs), and trifluoroacetic acid (TFA) in the AREc32 in vitro bioassay expressed as relative effect potency REP = IC10(STG)/IC10(TP). Error bars denote standard errors. ‘*’ indicates that REP < 12% for TP449 as the highest tested concentration did not reach 10% cytotoxicity.

Journal: bioRxiv

Article Title: Sequential exposure to anoxic/oxic conditions leads to biotransformation and detoxification of sitagliptin in urban hyporheic zones

doi: 10.1101/2025.06.03.657625

Figure Lengend Snippet: Relative cytotoxicity of sitagliptin (STG), its transformation products (TPs), and trifluoroacetic acid (TFA) in the AREc32 in vitro bioassay expressed as relative effect potency REP = IC10(STG)/IC10(TP). Error bars denote standard errors. ‘*’ indicates that REP < 12% for TP449 as the highest tested concentration did not reach 10% cytotoxicity.

Article Snippet: TP449 (N-acetyl sitagliptin) was purchased from Enamine (Frankfurt (Main), Germany).

Techniques: Transformation Assay, In Vitro, Bioassay, Concentration Assay