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Image Search Results
Journal: The Journal of physiology
Article Title: Neurones in the supraoptic nucleus of the rat are regulated by a projection from the suprachiasmatic nucleus.
doi: 10.1111/j.1469-7793.1997.149bl.x
Figure Lengend Snippet: Figure 3. PSTHs to illustrate the effects of excitatory and inhibitory antagonists on the SCN- evoked responses of three continuously firing SON cells in vitro A, the non-NMDA antagonist CNQX (10 ìÒ) reduced the excitatory effects of SCN stimulation. The NMDA antagonist APV (10 ìÒ) did not influence the effects of SCN stimulation on this cell (B), but reduced the excitatory effects of SCN stimulation on three other cells (C). D, in another cell, bicuculline (20 ìÒ) blocked the inhibitory effects of SCN stimulation. (Bin width, 5 ms for A and B, 10 ms for C and 20 ms for D; stimulus at time 0; 300 sweeps.)
Article Snippet: The following drugs were used to antagonize different neurotransmitter agents: bicuculline methiodide (Sigma) to antagonize GABAA receptors; a¬_2-amino-5-phosphonovaleric acid (APV; Sigma) to antagonize
Techniques: In Vitro