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Image Search Results
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Difference between massively parallel shotgun sequencing (MPSS) and targeted massively parallel sequencing (TMPS). Genomics‐based non‐invasive prenatal testing (gNIPT) aims to count the number of copies of DNA fragments from the chromosomes of interest (chromosome 21 (Chrom. 21) in this example) present in circulating cell‐free DNA (ccfDNA) from a pregnant woman, relative to a reference set of chromosomes (Ref. Chrom.). DNA fragments circulating in maternal blood in the case of a euploid (left) and aneuploid (right) pregnancy are illustrated (top). MPSS produces a large number of sequence reads from all chromosomes while TMPS generates a larger proportion of reads from the chromosomes of interest (bottom). In both methods, sequence reads can be used to detect a slight excess of fetal genomic material coming from the chromosome of interest. Figure was created by FR.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Reported accuracy of commercially available genomics‐based non‐invasive prenatal tests a
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Current clinical pathway and three proposed uses of genomics‐based non‐invasive prenatal testing (gNIPT). Currently (on the left), pregnant women can have a prenatal screening test consisting of biomarkers or ultrasound, or both. For high‐risk pregnant women, an invasive diagnostic test (karyotyping) is offered. In the present review, we propose 3 different clinical pathways. First, gNIPT could be used as a triage test, to decide which pregnant women should receive further testing. Second, gNIPT could be used to replace current prenatal screening tests. Finally, gNIPT could be used to replace current invasive diagnostic tests (if diagnostic performance permits). At any point in a clinical pathway, a pregnant woman may decide not to proceed with other tests (not shown in the figure). Figure was designed by CL, JB, MB and YT.
Article Snippet: Index and
Techniques: Diagnostic Assay
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Characteristics of included studies by type of gNIPT
Article Snippet: Index and
Techniques: Multiplexing, Clinical Proteomics, Sequencing, Multiplex Assay, Next-Generation Sequencing, Biomarker Discovery, Software
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of T13
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Manufacturers of gNIPT used in the included studies by prior risk of fetal aneuploidy
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Reasons for patient exclusion
Article Snippet: Index and
Techniques: Amplification, Sequencing, Control, Sampling, Clinical Proteomics, Biomarker Discovery
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Proportion of pregnant women with a reference standard and assay failure during gNIPT process
Article Snippet: Index and
Techniques: Sampling
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of 45,X
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of autosomes aneuploidies (T21, T18 and T13 combined)
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of sex chromosome aneuploidies (45,X, 47,XXX, 47,XXY and 47,XYY combined) a
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Risk of bias and applicability concerns summary: review authors' judgements about each domain for each study included for targeted massively parallel sequencing (TMPS).
Article Snippet: Index and
Techniques: Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Risk of bias and applicability concerns (all tests included): review authors' judgements about each domains presented as percentages across included studies. MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Summary characteristics of included studies
Article Snippet: Index and
Techniques: Diagnostic Assay, Shotgun Sequencing, Sequencing, Sampling, Selection
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of T21
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of T18
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T21 in unselected pregnant women undergoing aneuploidy screening. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T21 in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T18 in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T13 in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for 45,X in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for 47,XXX, 47,XXY and 47,XYY in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Data for 47,XXX, 47,XXY and 47,XYY according to the prior risk of fetal aneuploidy and gNIPT approach
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for autosomes (T21, T18 and T13 combined) in unselected pregnant women undergoing aneuploidy screening. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Subgroup analyses of MPSS and TMPS (type of pregnancy and gestational age)
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for autosomes (T21, T18 and T13) in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for SCA (45,X, 47,XXX, 47,XXY and 47,XYY combined) in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of traditional screening tests for T21, T18 and T13 in unselected pregnant women undergoing aneuploidy screening. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of comparative studies of TMPS and traditional screening tests for autosomes (T21, T18 and T13 combined) in unselected pregnant women undergoing aneuploidy screening. FN: false negative, FP: false positive, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Direct comparisons of gNIPT and traditional screening tests for autosomes (T21, T18 and T13 combined) in unselected population of pregnant women undergoing aneuploidy screening
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of traditional screening tests for autosomes (T21, T18 and T13 combined) in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for autosomes (T21, T18 and T13 combined) in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T21, T18 or T13 in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for SCA (45,X, 47,XXX, 47,XXY and 47,XYY combined) in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for 45,X, 47,XXY or 47,XYY in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Sensitivity analyses
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS T21.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS T18.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS T13.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS 45,X.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS 47,XXX.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS 47,XXY.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS 47,XYY.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS all 7 aneuploidies.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS, autosomes.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: TMPS, SCA.
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Data tables by test
Article Snippet: Index and
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Difference between massively parallel shotgun sequencing (MPSS) and targeted massively parallel sequencing (TMPS). Genomics‐based non‐invasive prenatal testing (gNIPT) aims to count the number of copies of DNA fragments from the chromosomes of interest (chromosome 21 (Chrom. 21) in this example) present in circulating cell‐free DNA (ccfDNA) from a pregnant woman, relative to a reference set of chromosomes (Ref. Chrom.). DNA fragments circulating in maternal blood in the case of a euploid (left) and aneuploid (right) pregnancy are illustrated (top). MPSS produces a large number of sequence reads from all chromosomes while TMPS generates a larger proportion of reads from the chromosomes of interest (bottom). In both methods, sequence reads can be used to detect a slight excess of fetal genomic material coming from the chromosome of interest. Figure was created by FR.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Characteristics of included studies by type of gNIPT
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Multiplexing, Clinical Proteomics, Sequencing, Multiplex Assay, Next-Generation Sequencing, Biomarker Discovery, Software
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of T13
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Proportion of pregnant women with a reference standard and assay failure during gNIPT process
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Sampling
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of 45,X
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of autosomes aneuploidies (T21, T18 and T13 combined)
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of sex chromosome aneuploidies (45,X, 47,XXX, 47,XXY and 47,XYY combined) a
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Risk of bias and applicability concerns (all tests included): review authors' judgements about each domains presented as percentages across included studies. MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Summary characteristics of included studies
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Diagnostic Assay, Shotgun Sequencing, Sequencing, Sampling, Selection
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of T21
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Performance of gNIPT for detection of T18
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T21 in unselected pregnant women undergoing aneuploidy screening. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T21 in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T18 in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T13 in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for 45,X in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for 47,XXX, 47,XXY and 47,XYY in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Data for 47,XXX, 47,XXY and 47,XYY according to the prior risk of fetal aneuploidy and gNIPT approach
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for autosomes (T21, T18 and T13 combined) in unselected pregnant women undergoing aneuploidy screening. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Subgroup analyses of MPSS and TMPS (type of pregnancy and gestational age)
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for autosomes (T21, T18 and T13) in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for SCA (45,X, 47,XXX, 47,XXY and 47,XYY combined) in pregnant women selected at high risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of traditional screening tests for T21, T18 and T13 in unselected pregnant women undergoing aneuploidy screening. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Direct comparisons of gNIPT and traditional screening tests for autosomes (T21, T18 and T13 combined) in unselected population of pregnant women undergoing aneuploidy screening
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of traditional screening tests for autosomes (T21, T18 and T13 combined) in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for autosomes (T21, T18 and T13 combined) in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for T21, T18 or T13 in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for SCA (45,X, 47,XXX, 47,XXY and 47,XYY combined) in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Forest plot of MPSS and TMPS for 45,X, 47,XXY or 47,XYY in pregnant women with mixed prior risk of fetal aneuploidy. FN: false negative, FP: false positive, MPSS: massively parallel shotgun sequencing, TMPS: targeted massively parallel sequencing, TN: true negative and TP: true positive.
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques: Shotgun Sequencing, Sequencing
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Sensitivity analyses
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: The Cochrane Database of Systematic Reviews
Article Title: Genomics‐based non‐invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
doi: 10.1002/14651858.CD011767.pub2
Figure Lengend Snippet: Data tables by test
Article Snippet: Index and comparator tests , gNIPT by TMPS or
Techniques:
Journal: Materials
Article Title: Modulation of the Structure of the Conjugated Polymer TMP and the Effect of Its Structure on the Catalytic Performance of TMP–TiO 2 under Visible Light: Catalyst Preparation, Performance and Mechanism
doi: 10.3390/ma16041563
Figure Lengend Snippet: ( a ) Fourier transform infrared spectroscopy (FT-IR) of melamine (M), tricarbonyl chloride (TMC), and trimesoyl chloride–melamine copolymer (TMP) after baseline correction (500–4000 cm −1 ); ( b ) FT-IR spectra of M, TMC, and TMP after baseline correction (900–1600 cm −1 ).
Article Snippet: In this work, in order to investigate the effect of CP structural changes on the photocatalytic performance of TiO 2 under visible light,
Techniques: Fourier Transform Infrared Spectroscopy, Spectroscopy