thiq Search Results


ketones  (Enamine Ltd)
90
Enamine Ltd ketones
Ketones, supplied by Enamine Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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thiq  (Tocris)
93
Tocris thiq
Thiq, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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thiq  (MedChemExpress)
93
MedChemExpress thiq

Thiq, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1 2 3 4 tetrahydroisoquinoline  (Chem Impex International)
95
Chem Impex International 1 2 3 4 tetrahydroisoquinoline

1 2 3 4 Tetrahydroisoquinoline, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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thiq  (Santa Cruz Biotechnology)
92
Santa Cruz Biotechnology thiq
Subtypes of MCR responsible for the α-MSH effect. ( a ) Single-stranded cDNA was generated from total RNA isolated from L6-S1 spinal cord tissue using reverse transcriptase (RT +) and amplified using PCR with primer pairs specific for rat Mc1r - Mc5r and Pomc . Amplified products of Mc1r , Mc4r and Pomc were observed in appropriate sizes. The reactions without reverse transcriptase (RT-) were analysed with PCR as a negative control. ( b ) Summarised graph of number of propulsive contractions during a period of 30 min after i.t. of <t>saline,</t> <t>BMS470539</t> (MC1R agonist, 30 nmol), <t>THIQ</t> (MC4R agonist, 30 nmol) and SHU9119 (MC1R agonist and MC4R antagonist, 3 nmol). BMS470539 and SHU9119, but not THIQ, significantly increased the number of propulsive contractions compared to that in the saline group. Each open circle (○) indicates a result from an individual rat, and the black bar shows the median. *Denotes a significant difference from the saline group ( P < 0.05). Five rats were used in each group.
Thiq, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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thiq  (TargetMol)
91
TargetMol thiq
Subtypes of MCR responsible for the α-MSH effect. ( a ) Single-stranded cDNA was generated from total RNA isolated from L6-S1 spinal cord tissue using reverse transcriptase (RT +) and amplified using PCR with primer pairs specific for rat Mc1r - Mc5r and Pomc . Amplified products of Mc1r , Mc4r and Pomc were observed in appropriate sizes. The reactions without reverse transcriptase (RT-) were analysed with PCR as a negative control. ( b ) Summarised graph of number of propulsive contractions during a period of 30 min after i.t. of <t>saline,</t> <t>BMS470539</t> (MC1R agonist, 30 nmol), <t>THIQ</t> (MC4R agonist, 30 nmol) and SHU9119 (MC1R agonist and MC4R antagonist, 3 nmol). BMS470539 and SHU9119, but not THIQ, significantly increased the number of propulsive contractions compared to that in the saline group. Each open circle (○) indicates a result from an individual rat, and the black bar shows the median. *Denotes a significant difference from the saline group ( P < 0.05). Five rats were used in each group.
Thiq, supplied by TargetMol, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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thiq - by Bioz Stars, 2026-02
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mono-n-alkylated tetrahydroisoquinoline (thiq) compounds  (Eli Lilly)
90
Eli Lilly mono-n-alkylated tetrahydroisoquinoline (thiq) compounds
Subtypes of MCR responsible for the α-MSH effect. ( a ) Single-stranded cDNA was generated from total RNA isolated from L6-S1 spinal cord tissue using reverse transcriptase (RT +) and amplified using PCR with primer pairs specific for rat Mc1r - Mc5r and Pomc . Amplified products of Mc1r , Mc4r and Pomc were observed in appropriate sizes. The reactions without reverse transcriptase (RT-) were analysed with PCR as a negative control. ( b ) Summarised graph of number of propulsive contractions during a period of 30 min after i.t. of <t>saline,</t> <t>BMS470539</t> (MC1R agonist, 30 nmol), <t>THIQ</t> (MC4R agonist, 30 nmol) and SHU9119 (MC1R agonist and MC4R antagonist, 3 nmol). BMS470539 and SHU9119, but not THIQ, significantly increased the number of propulsive contractions compared to that in the saline group. Each open circle (○) indicates a result from an individual rat, and the black bar shows the median. *Denotes a significant difference from the saline group ( P < 0.05). Five rats were used in each group.
Mono N Alkylated Tetrahydroisoquinoline (Thiq) Compounds, supplied by Eli Lilly, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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spectro-electrochemical (sec) uv-vis absorption spectrum of thiq  (SPECTRO Analytical)
90
SPECTRO Analytical spectro-electrochemical (sec) uv-vis absorption spectrum of thiq
Subtypes of MCR responsible for the α-MSH effect. ( a ) Single-stranded cDNA was generated from total RNA isolated from L6-S1 spinal cord tissue using reverse transcriptase (RT +) and amplified using PCR with primer pairs specific for rat Mc1r - Mc5r and Pomc . Amplified products of Mc1r , Mc4r and Pomc were observed in appropriate sizes. The reactions without reverse transcriptase (RT-) were analysed with PCR as a negative control. ( b ) Summarised graph of number of propulsive contractions during a period of 30 min after i.t. of <t>saline,</t> <t>BMS470539</t> (MC1R agonist, 30 nmol), <t>THIQ</t> (MC4R agonist, 30 nmol) and SHU9119 (MC1R agonist and MC4R antagonist, 3 nmol). BMS470539 and SHU9119, but not THIQ, significantly increased the number of propulsive contractions compared to that in the saline group. Each open circle (○) indicates a result from an individual rat, and the black bar shows the median. *Denotes a significant difference from the saline group ( P < 0.05). Five rats were used in each group.
Spectro Electrochemical (Sec) Uv Vis Absorption Spectrum Of Thiq, supplied by SPECTRO Analytical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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4-phenyl-1,2,3,4-tetrahydroisoquinolines thiq  (Verlag GmbH)
90
Verlag GmbH 4-phenyl-1,2,3,4-tetrahydroisoquinolines thiq
Subtypes of MCR responsible for the α-MSH effect. ( a ) Single-stranded cDNA was generated from total RNA isolated from L6-S1 spinal cord tissue using reverse transcriptase (RT +) and amplified using PCR with primer pairs specific for rat Mc1r - Mc5r and Pomc . Amplified products of Mc1r , Mc4r and Pomc were observed in appropriate sizes. The reactions without reverse transcriptase (RT-) were analysed with PCR as a negative control. ( b ) Summarised graph of number of propulsive contractions during a period of 30 min after i.t. of <t>saline,</t> <t>BMS470539</t> (MC1R agonist, 30 nmol), <t>THIQ</t> (MC4R agonist, 30 nmol) and SHU9119 (MC1R agonist and MC4R antagonist, 3 nmol). BMS470539 and SHU9119, but not THIQ, significantly increased the number of propulsive contractions compared to that in the saline group. Each open circle (○) indicates a result from an individual rat, and the black bar shows the median. *Denotes a significant difference from the saline group ( P < 0.05). Five rats were used in each group.
4 Phenyl 1,2,3,4 Tetrahydroisoquinolines Thiq, supplied by Verlag GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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thiq set 4  (Arkat USA Inc)
90
Arkat USA Inc thiq set 4
Subtypes of MCR responsible for the α-MSH effect. ( a ) Single-stranded cDNA was generated from total RNA isolated from L6-S1 spinal cord tissue using reverse transcriptase (RT +) and amplified using PCR with primer pairs specific for rat Mc1r - Mc5r and Pomc . Amplified products of Mc1r , Mc4r and Pomc were observed in appropriate sizes. The reactions without reverse transcriptase (RT-) were analysed with PCR as a negative control. ( b ) Summarised graph of number of propulsive contractions during a period of 30 min after i.t. of <t>saline,</t> <t>BMS470539</t> (MC1R agonist, 30 nmol), <t>THIQ</t> (MC4R agonist, 30 nmol) and SHU9119 (MC1R agonist and MC4R antagonist, 3 nmol). BMS470539 and SHU9119, but not THIQ, significantly increased the number of propulsive contractions compared to that in the saline group. Each open circle (○) indicates a result from an individual rat, and the black bar shows the median. *Denotes a significant difference from the saline group ( P < 0.05). Five rats were used in each group.
Thiq Set 4, supplied by Arkat USA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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thiq set 4 - by Bioz Stars, 2026-02
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thiq  (LEO Pharma)
90
LEO Pharma thiq
Subtypes of MCR responsible for the α-MSH effect. ( a ) Single-stranded cDNA was generated from total RNA isolated from L6-S1 spinal cord tissue using reverse transcriptase (RT +) and amplified using PCR with primer pairs specific for rat Mc1r - Mc5r and Pomc . Amplified products of Mc1r , Mc4r and Pomc were observed in appropriate sizes. The reactions without reverse transcriptase (RT-) were analysed with PCR as a negative control. ( b ) Summarised graph of number of propulsive contractions during a period of 30 min after i.t. of <t>saline,</t> <t>BMS470539</t> (MC1R agonist, 30 nmol), <t>THIQ</t> (MC4R agonist, 30 nmol) and SHU9119 (MC1R agonist and MC4R antagonist, 3 nmol). BMS470539 and SHU9119, but not THIQ, significantly increased the number of propulsive contractions compared to that in the saline group. Each open circle (○) indicates a result from an individual rat, and the black bar shows the median. *Denotes a significant difference from the saline group ( P < 0.05). Five rats were used in each group.
Thiq, supplied by LEO Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
thiq - by Bioz Stars, 2026-02
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Image Search Results


Journal: eLife

Article Title: High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery

doi: 10.7554/eLife.104725

Figure Lengend Snippet:

Article Snippet: chemical compound, drug , THIQ , MedChemExpress , CAS:312637-48-2 , .

Techniques: Luciferase, Software

Subtypes of MCR responsible for the α-MSH effect. ( a ) Single-stranded cDNA was generated from total RNA isolated from L6-S1 spinal cord tissue using reverse transcriptase (RT +) and amplified using PCR with primer pairs specific for rat Mc1r - Mc5r and Pomc . Amplified products of Mc1r , Mc4r and Pomc were observed in appropriate sizes. The reactions without reverse transcriptase (RT-) were analysed with PCR as a negative control. ( b ) Summarised graph of number of propulsive contractions during a period of 30 min after i.t. of saline, BMS470539 (MC1R agonist, 30 nmol), THIQ (MC4R agonist, 30 nmol) and SHU9119 (MC1R agonist and MC4R antagonist, 3 nmol). BMS470539 and SHU9119, but not THIQ, significantly increased the number of propulsive contractions compared to that in the saline group. Each open circle (○) indicates a result from an individual rat, and the black bar shows the median. *Denotes a significant difference from the saline group ( P < 0.05). Five rats were used in each group.

Journal: Scientific Reports

Article Title: α-MSH-induced activation of spinal MC1R but not MC4R enhances colorectal motility in anaesthetised rats

doi: 10.1038/s41598-020-80020-x

Figure Lengend Snippet: Subtypes of MCR responsible for the α-MSH effect. ( a ) Single-stranded cDNA was generated from total RNA isolated from L6-S1 spinal cord tissue using reverse transcriptase (RT +) and amplified using PCR with primer pairs specific for rat Mc1r - Mc5r and Pomc . Amplified products of Mc1r , Mc4r and Pomc were observed in appropriate sizes. The reactions without reverse transcriptase (RT-) were analysed with PCR as a negative control. ( b ) Summarised graph of number of propulsive contractions during a period of 30 min after i.t. of saline, BMS470539 (MC1R agonist, 30 nmol), THIQ (MC4R agonist, 30 nmol) and SHU9119 (MC1R agonist and MC4R antagonist, 3 nmol). BMS470539 and SHU9119, but not THIQ, significantly increased the number of propulsive contractions compared to that in the saline group. Each open circle (○) indicates a result from an individual rat, and the black bar shows the median. *Denotes a significant difference from the saline group ( P < 0.05). Five rats were used in each group.

Article Snippet: Inc., Osaka, Japan), BMS470539 dihydrochloride (Tocris Bioscience, Bristol, UK), THIQ (Santa Cruz Biotechnology, Inc., TX, USA) and SHU9119 (Abcam, Cambridge, UK). α-Chloralose was solubilised with 10% 2-hydroxypropyl-beta-cyclodextrin (Fujifilm Wako Pure Chemical Corp., Osaka, Japan) and then made up with 0.9% saline for infusion.

Techniques: Generated, Isolation, Reverse Transcription, Amplification, Negative Control, Saline