Journal: Methods in Molecular Biology (Clifton, N.j.)

Article Title: Epidermal Permeability Barrier (EPB) measurement in mammalian skin

doi: 10.1007/978-1-61779-191-8_4

Figure Lengend Snippet: The tewameter probe is touched on the skin surface and the readings are noted on the screen of a multiprobe adaptor (21) system.

Article Snippet: TEWL is the most important and sensitive parameter for evaluating the integrity of the EPB in all conditions in laboratory mice, rats and in humans (see Notes 7 and 8 ). list-behavior=enumerated prefix-word= mark-type=decimal max-label-size=0 Dorsal and ventral skin TEWL were determined on E17.5 and E18.5 embryos, neonatal or adult mice (after shaving to remove the hair) with a tewameter (Acaderm Inc., USA) equipped with a TEWL probe (see ). fig ft0 fig mode=article f1 fig/graphic|fig/alternatives/graphic mode="anchored" m1 Open in a separate window caption a7 caption a8 Measurement of TEWL using a tewameter The tewameter probe is touched on the skin surface and the readings are noted on the screen of a multiprobe adaptor ( 21 ) system.

Techniques: