tcdf function in Search Results


unknown function duf916 cell surface protein cell surface protein  (ATCC)
96
ATCC unknown function duf916 cell surface protein cell surface protein
Unknown Function Duf916 Cell Surface Protein Cell Surface Protein, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gene exp aip hs00610222 m1  (Thermo Fisher)
90
Thermo Fisher gene exp aip hs00610222 m1
Genealogy: identification of a functional <t>AIP</t> mutation that may disrupt the cAMP signaling pathway. A - The index patient developed acromegaly, adrenocortical carcinoma and B-cell lymphoma. One of her daughters had acromegaly due to a large and invasive somatotropinoma. B - The known AIP functional mutation c.241C>T (R81X) was identified in genomic DNA samples from both patients (mother and daughter) with acromegaly but not in the three unaffected family members.
Gene Exp Aip Hs00610222 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
gene exp aip hs00610222 m1 - by Bioz Stars, 2026-05
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thermal conductivity detector  (Pfeiffer Vacuum)
90
Pfeiffer Vacuum thermal conductivity detector
Genealogy: identification of a functional <t>AIP</t> mutation that may disrupt the cAMP signaling pathway. A - The index patient developed acromegaly, adrenocortical carcinoma and B-cell lymphoma. One of her daughters had acromegaly due to a large and invasive somatotropinoma. B - The known AIP functional mutation c.241C>T (R81X) was identified in genomic DNA samples from both patients (mother and daughter) with acromegaly but not in the three unaffected family members.
Thermal Conductivity Detector, supplied by Pfeiffer Vacuum, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
thermal conductivity detector - by Bioz Stars, 2026-05
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functional tcd  (Deppe GmbH)
90
Deppe GmbH functional tcd
Genealogy: identification of a functional <t>AIP</t> mutation that may disrupt the cAMP signaling pathway. A - The index patient developed acromegaly, adrenocortical carcinoma and B-cell lymphoma. One of her daughters had acromegaly due to a large and invasive somatotropinoma. B - The known AIP functional mutation c.241C>T (R81X) was identified in genomic DNA samples from both patients (mother and daughter) with acromegaly but not in the three unaffected family members.
Functional Tcd, supplied by Deppe GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/functional tcd/product/Deppe GmbH
Average 90 stars, based on 1 article reviews
functional tcd - by Bioz Stars, 2026-05
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tcd4 cells  (Cytek Biosciences)
98
Cytek Biosciences tcd4 cells
Genealogy: identification of a functional <t>AIP</t> mutation that may disrupt the cAMP signaling pathway. A - The index patient developed acromegaly, adrenocortical carcinoma and B-cell lymphoma. One of her daughters had acromegaly due to a large and invasive somatotropinoma. B - The known AIP functional mutation c.241C>T (R81X) was identified in genomic DNA samples from both patients (mother and daughter) with acromegaly but not in the three unaffected family members.
Tcd4 Cells, supplied by Cytek Biosciences, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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auto-measure function on the acuson sequoia machine  (Acuson Corporation)
90
Acuson Corporation auto-measure function on the acuson sequoia machine
Genealogy: identification of a functional <t>AIP</t> mutation that may disrupt the cAMP signaling pathway. A - The index patient developed acromegaly, adrenocortical carcinoma and B-cell lymphoma. One of her daughters had acromegaly due to a large and invasive somatotropinoma. B - The known AIP functional mutation c.241C>T (R81X) was identified in genomic DNA samples from both patients (mother and daughter) with acromegaly but not in the three unaffected family members.
Auto Measure Function On The Acuson Sequoia Machine, supplied by Acuson Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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micro-volume thermal conductivity detector tcd  (VICI AG)
90
VICI AG micro-volume thermal conductivity detector tcd
Genealogy: identification of a functional <t>AIP</t> mutation that may disrupt the cAMP signaling pathway. A - The index patient developed acromegaly, adrenocortical carcinoma and B-cell lymphoma. One of her daughters had acromegaly due to a large and invasive somatotropinoma. B - The known AIP functional mutation c.241C>T (R81X) was identified in genomic DNA samples from both patients (mother and daughter) with acromegaly but not in the three unaffected family members.
Micro Volume Thermal Conductivity Detector Tcd, supplied by VICI AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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gas chromatograph gc7900  (Techcomp India)
90
Techcomp India gas chromatograph gc7900
Genealogy: identification of a functional <t>AIP</t> mutation that may disrupt the cAMP signaling pathway. A - The index patient developed acromegaly, adrenocortical carcinoma and B-cell lymphoma. One of her daughters had acromegaly due to a large and invasive somatotropinoma. B - The known AIP functional mutation c.241C>T (R81X) was identified in genomic DNA samples from both patients (mother and daughter) with acromegaly but not in the three unaffected family members.
Gas Chromatograph Gc7900, supplied by Techcomp India, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Genealogy: identification of a functional AIP mutation that may disrupt the cAMP signaling pathway. A - The index patient developed acromegaly, adrenocortical carcinoma and B-cell lymphoma. One of her daughters had acromegaly due to a large and invasive somatotropinoma. B - The known AIP functional mutation c.241C>T (R81X) was identified in genomic DNA samples from both patients (mother and daughter) with acromegaly but not in the three unaffected family members.

Journal: Clinics

Article Title: Isolated familial somatotropinoma: 11q13-loh and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis

doi: 10.1590/S1807-59322010000400010

Figure Lengend Snippet: Genealogy: identification of a functional AIP mutation that may disrupt the cAMP signaling pathway. A - The index patient developed acromegaly, adrenocortical carcinoma and B-cell lymphoma. One of her daughters had acromegaly due to a large and invasive somatotropinoma. B - The known AIP functional mutation c.241C>T (R81X) was identified in genomic DNA samples from both patients (mother and daughter) with acromegaly but not in the three unaffected family members.

Article Snippet: Quantitative PCR (qPCR) was performed with an ABI Prism 7700 Sequence Detector using the TaqMan Gene Expression Assays (Hs00610222_m1 for AIP and 43263 for β-actin) following the manufacturer’s instructions (Applied Biosystems).

Techniques: Functional Assay, Mutagenesis

Loss of AIP in the familial somatotropinoma. A - The MRI of the index patient’s daughter revealed a large and invasive pituitary adenoma (so-matotropinoma) that was resistant to treatment with a somatostatin analog. She inherited the heterozygous R81X AIP germline mutation from the index case. B - The sequence analysis of AIP in tumoral DNA samples revealed that only the R81X-mutated allele (t) was present in the somatotropinoma, indicating somatic loss and inactivation of wild-type AIP . C - The immunohistochemical analysis showed AIP protein expression in the normal pituitary and a GH-secreting pituitary adenoma of a patient with sporadic acromegaly without AIP mutation. The somatotropinoma of the patient harboring the R81X germline mutation and the somatic loss of the gene presented low AIP protein expression.

Journal: Clinics

Article Title: Isolated familial somatotropinoma: 11q13-loh and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis

doi: 10.1590/S1807-59322010000400010

Figure Lengend Snippet: Loss of AIP in the familial somatotropinoma. A - The MRI of the index patient’s daughter revealed a large and invasive pituitary adenoma (so-matotropinoma) that was resistant to treatment with a somatostatin analog. She inherited the heterozygous R81X AIP germline mutation from the index case. B - The sequence analysis of AIP in tumoral DNA samples revealed that only the R81X-mutated allele (t) was present in the somatotropinoma, indicating somatic loss and inactivation of wild-type AIP . C - The immunohistochemical analysis showed AIP protein expression in the normal pituitary and a GH-secreting pituitary adenoma of a patient with sporadic acromegaly without AIP mutation. The somatotropinoma of the patient harboring the R81X germline mutation and the somatic loss of the gene presented low AIP protein expression.

Article Snippet: Quantitative PCR (qPCR) was performed with an ABI Prism 7700 Sequence Detector using the TaqMan Gene Expression Assays (Hs00610222_m1 for AIP and 43263 for β-actin) following the manufacturer’s instructions (Applied Biosystems).

Techniques: Mutagenesis, Sequencing, Immunohistochemical staining, Expressing

Loss of AIP in the adrenocortical tumor. A - An abdominal imaging scan of the index case when she presented with virilization and high serum levels of adrenal steroids. The scan revealed a large heterogeneous mass (9.0 cm x 8.9 cm) in the right adrenal gland, which was surgically excised and histopathologically classified as adrenocortical carcinoma. B - Sequence and microsatellite (D11S1258 AIP -flanking marker) analyses of DNA samples from the tumor revealed loss of the wild-type AIP allele. C - The 2 -δ δ CT method was used to compare AIP mRNA expression in pooled normal pituitary glands (Ct AIP=25.66, Ct β-actin=24.24), pooled normal adrenal glands (Ct AIP=25.42; Ct β-actin=22.49) and the adrenocortical carcinoma from the index case, in whom the AIP wild-type allele was lost (Ct AIP=31.53, Ct β-actin=27.28). The mean Ct value of the normal adrenal pool was used as a reference (1.0), by comparison, there was decreased AIP expression in the adrenocortical carcinoma (0.48). D - Immunohistochemistry using the AIP antibody showed low/ moderate staining in a normal adrenal gland obtained from autopsy. A complete loss of AIP immunoreactivity was observed in the adrenocortical carcinoma from the index patient, which stained positive for Melan A and 35betaH11, which were used as positive controls.

Journal: Clinics

Article Title: Isolated familial somatotropinoma: 11q13-loh and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis

doi: 10.1590/S1807-59322010000400010

Figure Lengend Snippet: Loss of AIP in the adrenocortical tumor. A - An abdominal imaging scan of the index case when she presented with virilization and high serum levels of adrenal steroids. The scan revealed a large heterogeneous mass (9.0 cm x 8.9 cm) in the right adrenal gland, which was surgically excised and histopathologically classified as adrenocortical carcinoma. B - Sequence and microsatellite (D11S1258 AIP -flanking marker) analyses of DNA samples from the tumor revealed loss of the wild-type AIP allele. C - The 2 -δ δ CT method was used to compare AIP mRNA expression in pooled normal pituitary glands (Ct AIP=25.66, Ct β-actin=24.24), pooled normal adrenal glands (Ct AIP=25.42; Ct β-actin=22.49) and the adrenocortical carcinoma from the index case, in whom the AIP wild-type allele was lost (Ct AIP=31.53, Ct β-actin=27.28). The mean Ct value of the normal adrenal pool was used as a reference (1.0), by comparison, there was decreased AIP expression in the adrenocortical carcinoma (0.48). D - Immunohistochemistry using the AIP antibody showed low/ moderate staining in a normal adrenal gland obtained from autopsy. A complete loss of AIP immunoreactivity was observed in the adrenocortical carcinoma from the index patient, which stained positive for Melan A and 35betaH11, which were used as positive controls.

Article Snippet: Quantitative PCR (qPCR) was performed with an ABI Prism 7700 Sequence Detector using the TaqMan Gene Expression Assays (Hs00610222_m1 for AIP and 43263 for β-actin) following the manufacturer’s instructions (Applied Biosystems).

Techniques: Imaging, Sequencing, Marker, Expressing, Comparison, Immunohistochemistry, Staining

Maintenance of heterozygosity and positive AIP immunostaining in the B-cell non-Hodgkin lymphoma of the R81X AIP mutated IFS patient.

Journal: Clinics

Article Title: Isolated familial somatotropinoma: 11q13-loh and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesis

doi: 10.1590/S1807-59322010000400010

Figure Lengend Snippet: Maintenance of heterozygosity and positive AIP immunostaining in the B-cell non-Hodgkin lymphoma of the R81X AIP mutated IFS patient.

Article Snippet: Quantitative PCR (qPCR) was performed with an ABI Prism 7700 Sequence Detector using the TaqMan Gene Expression Assays (Hs00610222_m1 for AIP and 43263 for β-actin) following the manufacturer’s instructions (Applied Biosystems).

Techniques: Immunostaining