su 16f Search Results


su 16f  (1PlusChem LLC)
N/A
SU 16f
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bibo 3304  (Tocris)
93
Tocris bibo 3304
Bibo 3304, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/su+16f/SU+16f/pmc11098623-42-3-5
Average 93 stars, based on 1 article reviews
bibo 3304 - by Bioz Stars, 2026-09
93/100 stars
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pdgfrβ inhibitor  (Tocris)
99
Tocris pdgfrβ inhibitor
<t>PDGF</t> selectively enhanced the migration of hBMSC-TERT +Bone versus hBMSC-TERT –Bone . a Transwell migration ability of hBMSC-TERT +Bone versus hBMSC-TERT –Bone toward the chemoattractants including: IGF-1 (10 ng/ml), SDF-1 (100 ng/ml), PDGF-BB (100 ng/ml), and TNFα (10 ng/ml). Photomicrographs represent images of the migrated cells for each condition. b Transwell migration assay of hBMSC-TERT +Bone and hBMSC-TERT –Bone cells toward different subtypes of PDGF recombinant protein (100 ng/ml). PDGF isoforms have applied either in the lower chamber (PDGF-AA, PDGF-AB, PDGF-BB) of the transwell migration assay to examine the migratory capacity of the cells or applied to both lower and upper chambers of the assay (PDGF-AA + PDGF-AA, PDGF-AB + PDGF-Ab, PDGF-BB + PDGF-BB) to inhibit the migration. c Dose-dependent effect of PDGF-BB (10, 50, or 100 ng/ml) on the transwell migration of hBMSC-TERT +Bone or hBMSC-TERT –Bone cells. d Dose-dependent effect of SU-16f inhibitor (a selective inhibitor for <t>PDGFRβ)</t> on the transwell migration of hBMSC-TERT +Bone or hBMSC-TERT –Bone cells. Data presented as mean ± SEM of at least three independent experiments (* p ≤0.05, ** p ≤0.01, *** p ≤0.005, **** p ≤0.001, as compared with control). DMSO dimethyl sulfoxide, hBMSC human bone marrow stromal stem cells, IGF1 insulin-like growth factor 1, PDGF platelet-derived growth factor, SDF1 stromal cell-derived factor 1, TNFα tumor necrosis factor alpha
Pdgfrβ Inhibitor, supplied by Tocris, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/su+16f/SU+16f/pmc04599318-129-29-32
Average 99 stars, based on 1 article reviews
pdgfrβ inhibitor - by Bioz Stars, 2026-09
99/100 stars
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su 16f  (Cayman Chemical)
N/A
SU 16f
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su 16f  (BOC Sciences)
N/A
SU 16f is a potent and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC50 = 10 nM), displaying > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. It also
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su 16f  (Santa Cruz Biotechnology)
N/A
SU 16f is a selective PDGFRβ inhibitor with an IC50=10nM. In vitro studies demonstrate that SU 16f also inhibits HUVEC and NIH3T3 cell proliferation with an IC50=0.11μM. In addition, SU 16f displays 14 fold selectivity
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su 16f  (Aladdin Scientific Corporation)
N/A
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Image Search Results


PDGF selectively enhanced the migration of hBMSC-TERT +Bone versus hBMSC-TERT –Bone . a Transwell migration ability of hBMSC-TERT +Bone versus hBMSC-TERT –Bone toward the chemoattractants including: IGF-1 (10 ng/ml), SDF-1 (100 ng/ml), PDGF-BB (100 ng/ml), and TNFα (10 ng/ml). Photomicrographs represent images of the migrated cells for each condition. b Transwell migration assay of hBMSC-TERT +Bone and hBMSC-TERT –Bone cells toward different subtypes of PDGF recombinant protein (100 ng/ml). PDGF isoforms have applied either in the lower chamber (PDGF-AA, PDGF-AB, PDGF-BB) of the transwell migration assay to examine the migratory capacity of the cells or applied to both lower and upper chambers of the assay (PDGF-AA + PDGF-AA, PDGF-AB + PDGF-Ab, PDGF-BB + PDGF-BB) to inhibit the migration. c Dose-dependent effect of PDGF-BB (10, 50, or 100 ng/ml) on the transwell migration of hBMSC-TERT +Bone or hBMSC-TERT –Bone cells. d Dose-dependent effect of SU-16f inhibitor (a selective inhibitor for PDGFRβ) on the transwell migration of hBMSC-TERT +Bone or hBMSC-TERT –Bone cells. Data presented as mean ± SEM of at least three independent experiments (* p ≤0.05, ** p ≤0.01, *** p ≤0.005, **** p ≤0.001, as compared with control). DMSO dimethyl sulfoxide, hBMSC human bone marrow stromal stem cells, IGF1 insulin-like growth factor 1, PDGF platelet-derived growth factor, SDF1 stromal cell-derived factor 1, TNFα tumor necrosis factor alpha

Journal: Stem Cell Research & Therapy

Article Title: Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells

doi: 10.1186/s13287-015-0188-9

Figure Lengend Snippet: PDGF selectively enhanced the migration of hBMSC-TERT +Bone versus hBMSC-TERT –Bone . a Transwell migration ability of hBMSC-TERT +Bone versus hBMSC-TERT –Bone toward the chemoattractants including: IGF-1 (10 ng/ml), SDF-1 (100 ng/ml), PDGF-BB (100 ng/ml), and TNFα (10 ng/ml). Photomicrographs represent images of the migrated cells for each condition. b Transwell migration assay of hBMSC-TERT +Bone and hBMSC-TERT –Bone cells toward different subtypes of PDGF recombinant protein (100 ng/ml). PDGF isoforms have applied either in the lower chamber (PDGF-AA, PDGF-AB, PDGF-BB) of the transwell migration assay to examine the migratory capacity of the cells or applied to both lower and upper chambers of the assay (PDGF-AA + PDGF-AA, PDGF-AB + PDGF-Ab, PDGF-BB + PDGF-BB) to inhibit the migration. c Dose-dependent effect of PDGF-BB (10, 50, or 100 ng/ml) on the transwell migration of hBMSC-TERT +Bone or hBMSC-TERT –Bone cells. d Dose-dependent effect of SU-16f inhibitor (a selective inhibitor for PDGFRβ) on the transwell migration of hBMSC-TERT +Bone or hBMSC-TERT –Bone cells. Data presented as mean ± SEM of at least three independent experiments (* p ≤0.05, ** p ≤0.01, *** p ≤0.005, **** p ≤0.001, as compared with control). DMSO dimethyl sulfoxide, hBMSC human bone marrow stromal stem cells, IGF1 insulin-like growth factor 1, PDGF platelet-derived growth factor, SDF1 stromal cell-derived factor 1, TNFα tumor necrosis factor alpha

Article Snippet: The following concentrations of factors were used: PDGF-BB (PeproTech GmbH Hamburg, Germany), 10–100 ng/ml; PDGF-AA (PeproTech GmbH Hamburg, Germany), 100 ng/ml; PDGF-AB (PeproTech GmbH Hamburg, Germany), 100 ng/ml; and PDGFRβ inhibitor (SU16f; Tocris), 10–200 nM.

Techniques: Migration, Transwell Migration Assay, Recombinant, Control, Derivative Assay

PDGFRβ as a potential marker for enhancing hBMSC migration. a FACS analysis of PDGFRβ in hBMSC-TERT –Bone before and after enrichment for PDGFRβ + cells. b MACS PDGFRβ + -enriched cells from hBMSC-TERT –Bone were compared with PDGFRβ – cells for their migratory response toward different PDGF isoforms (PDGF-AA, PDGF-BB, or PDGF-AB) (100 ng/ml). Data presented as mean ± SEM of at least three independent experiments (* p ≤0.05, ** p ≤0.01, ** p ≤0.005, as compared with control). PDGFR platelet-derived growth factor receptor

Journal: Stem Cell Research & Therapy

Article Title: Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells

doi: 10.1186/s13287-015-0188-9

Figure Lengend Snippet: PDGFRβ as a potential marker for enhancing hBMSC migration. a FACS analysis of PDGFRβ in hBMSC-TERT –Bone before and after enrichment for PDGFRβ + cells. b MACS PDGFRβ + -enriched cells from hBMSC-TERT –Bone were compared with PDGFRβ – cells for their migratory response toward different PDGF isoforms (PDGF-AA, PDGF-BB, or PDGF-AB) (100 ng/ml). Data presented as mean ± SEM of at least three independent experiments (* p ≤0.05, ** p ≤0.01, ** p ≤0.005, as compared with control). PDGFR platelet-derived growth factor receptor

Article Snippet: The following concentrations of factors were used: PDGF-BB (PeproTech GmbH Hamburg, Germany), 10–100 ng/ml; PDGF-AA (PeproTech GmbH Hamburg, Germany), 100 ng/ml; PDGF-AB (PeproTech GmbH Hamburg, Germany), 100 ng/ml; and PDGFRβ inhibitor (SU16f; Tocris), 10–200 nM.

Techniques: Marker, Migration, Control, Derivative Assay