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Image Search Results
Journal: Endocrinology
Article Title: The proximal promoter region of the gene encoding human 17beta-hydroxysteroid dehydrogenase type 1 contains GATA, AP-2, and Sp1 response elements: analysis of promoter function in choriocarcinoma cells.
doi: 10.1210/endo.138.8.5329
Figure Lengend Snippet: FIG. 7. Identification of the factors binding to the Sp1-binding site in the HSD17B1 promoter. Interaction of the HSD-mAP-2/Sp1 fragment (A) and the intact HSD-AP-2/Sp1 fragment (B) with JEG-3, JAR, and HeLa nuclear extracts in the absence (lanes 1, 6, and 11) and presence of antibodies against Sp1, Sp2, Sp3, and Sp4. The binding complexes and their supershifted forms were sep- arated from each other in 4% polyacryl- amide gel.
Article Snippet: The antibodies against the transcription factors GATA-2, GATA-3, AP-2, Sp1,
Techniques: Binding Assay