Journal: JMIR Mental Health

Article Title: Wearable and Mobile Technologies for the Evaluation and Treatment of Obsessive-Compulsive Disorder: Scoping Review

doi: 10.2196/45572

Figure Lengend Snippet: Studies with digital or mobile interventions, organized by publication year.

Article Snippet: Provenza et al [ ], 2021, United States , Adult men and women (31-40) , Summit RC+S (Medtronic); Apple Watch (Apple Inc); StriveStudy mobile app (Rune Labs); Honeycomb task app; actiCAP electroencephalogram cap (Brain Products GmbH); GoPro Hero 6 (GoPro Inc); H4n Pro 4-track Portable Recorder (Zoom Corp); and AFAR n computer-vision (Carnegie Mellon University) , Intracranial electrophysiology: passive collection through DBS device Heart rate, blood volume pulse, and acceleration: passive collection through Apple Watch OCD symptom severity: active collection through self-report via StriveStudy app Performance on cognitive and behavioral tasks: active collection through Honeycomb app Extracranial electrophysiology: passive collection through actiCAP Facial movements: passive collection through GoPro and AFAR Speech: passive collection through H4n recorder , Symptom burden: active collection through clinician-administered measures , Open-loop DBS to bilateral VC/VS or BNST o , Natural environment and outpatient , To identify the neural biomarkers of OCD through (1) the measurement of intracranial and extracranial electrophysiology, (2) self-reported OCD symptom burden, (3) objectively measured affective state, and (4) the evaluation of physiology for the purpose of developing an adaptive DBS for OCD , AFAR software estimated positive affect and head velocity, and these data were synchronized with blood volume pulse, electrocardiogram, electroencephalogram, LFP from DBS, and the acceleration of INS p Increase in positive affect and subjective positive feelings during DBS programming session in participant 5 Self-reports were synchronized to at-home, wirelessly streamed DBS LFP, routine at-home tasks, and psychophysiological tasks In total, across the 3 participants, over 1000 hours of at-home intracranial physiology was recorded 1 participant completed an at-home LFP recording for 3 continuous days; 41 OCD symptom intensity ratings were collected during this period (range 0-8); LFP frequency band power was examined in the minute before and after self-report; there was a strong negative correlation between power in the delta band and OCD symptom severity in both the left (R=−0.593) and right (R=−0.557) VC/VS; correlations to planned ERP exposures in this participant were also seen in the delta band.

Techniques: Software, Biomarker Assay

Journal: Supportive Care in Cancer

Article Title: Counting the social, psychological, and economic costs of COVID-19 for cancer patients

doi: 10.1007/s00520-022-07178-0

Figure Lengend Snippet: Extraction summary

Article Snippet: Yang S. et al. (2020) China Lymphoma , 1. To examine the impact of disrupted cancer care on anxiety and HRQoL of patients 2. Evaluate caregiver support and an online education programme of the Chinese Society of Clinical Oncology (CSCO) , Patient Cross-sectional N = 2532 subjects (1060 patients, 948 caregivers, and 524 members of the general public) > 20 years old , Primary data: questionnaire Web-based 17 to 19 April 2020 , • Online questionnaire using: • Zung Self-Rating Anxiety Scale (SAS) • EORTC QLQ-C30 instrument •Desc. stats • T -test • ANOVA • χ 2 tests • The Kendall tau-b correlation • Linear regression , • 56% of patients changed their routine hospital • 9% changed to a therapy of lower intensity • 4% switched to oral anti-lymphoma drugs • 13% delayed scheduled parenteral therapy • 37% delayed or postponed scheduled hospital visits • 24% experienced reduced therapy intensity including fewer drugs, reduced drug doses, a switch from parenteral to oral drugs, and/or therapy delay or discontinuation • 52% reported no change of their medical activities including physician visits, exams, and/or therapy • 33% if lymphoma patients had anxiety • Incidence of anxiety higher in lymphoma patients and their caregivers compared to members of the general public • More than 77% of respondents had minimal/moderate anxiety • Female sex, receiving therapy, reduced therapy intensity, and hospitalised patients were associated with more anxiety • Reduced therapy intensity was associated with worse HRQoL • Those who scored caregiver support and the online patient education programme high had better HRQoL • Paradoxically, lymphoma patients during the pandemic had better HRQoL than pre-pandemic controls • 39% were concerned about treatment disruption • 50% of patients were concerned about COVID-19 infection risk • Females were associated with more anxiety • Higher education level was associated with less anxiety • Social support resources for lymphoma patients included online patient support/discussion groups. Subjects who rated the quality of these online tools high had a better HRQoL.

Techniques: Extraction, Infection, Mann-Whitney U-Test, Modification, Isolation, Transmission Assay, Adjuvant, Dominant Negative Mutation, Virus, Biomarker Discovery, Activity Assay, Imaging, Disruption, T-Test