sdma Search Results


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EpiCypher anti sdma
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Immundiagnostik AG symmetric dimethylarginine sdma
Platelet reactivity, sP-selectin and endothelial biomarkers in patients on DAPT with ticagrelor and clopidogrel stratified by diabetes status
Symmetric Dimethylarginine Sdma, supplied by Immundiagnostik AG, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Toronto Research Chemicals sdma d6
Platelet reactivity, sP-selectin and endothelial biomarkers in patients on DAPT with ticagrelor and clopidogrel stratified by diabetes status
Sdma D6, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Enzo Biochem symmetric-dimethylarginine (sdma
(A) Heat map representation of substrates and methylated products of major SAM-derived transmethylation reactions (PEMT, GNMT, GAMT and PRMT) with HFHC diet for 52 weeks. (B) Levels of glycine, a substrate for GNMT, were decreased (p< 0.01) while the product sarcosine did not change between chow and HFHC group. (C) The gene expression of Gnmt , the most abundant methyltranserase in the liver, decreased significantly but only approached significance at the protein level (p = 0.06). (D) Levels of PE, the substrate for PEMT, was significantly reduced (p< 0.01) while PC trended down, resulting in a significant PC/PE ratio (p< 0.01), which suggests increase in PEMT activity There were no significant changes in the concentrations of guanidinoacetate and creatine, the substrate and product for GAMT, respectively. (E) The methylated products of PRMT activity, MMA and ADMA, were decreased significantly (p< 0.01 and p< 0.05) while the decrease in <t>SDMA</t> approached significance (p = 0.07). (F) The gene expression of Prmt1 , mainly responsible for the methylation of MMA and ADMA, decreased (p< 0.01) but the protein levels of PRMT1 increased significantly (p< 0.05). (G) Circulating ADMA was increased toward significance (p = 0.06), suggesting increased export to the circulation. Data are represented as mean ± SEM. Legend: arginine (Arg); asymmetric <t>dimethylarginine</t> (ADMA); creatine (Crea); glycine (Gly); glycine N-methyltransferase (GNMT); guanidinoacetate (GAA); guanidinoacetate methyltransferase (GAMT); homocysteine (Hcy); monomethylarginine (MMA); phosphatidylcholine (PC); phosphatidylethanolamine (PE); phosphatidylethanolamine methyltransferase (PEMT); protein arginine methyltransferase (PRMT); s-adenosylhomocysteine (SAH); s-adenosylmethionine (SAM); sarcosine (Sar); symmetric dimethylarginine (SDMA).
Symmetric Dimethylarginine (Sdma, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BioIVT Inc sdma in pooled charcoal stripped mongrel serum
(A) Heat map representation of substrates and methylated products of major SAM-derived transmethylation reactions (PEMT, GNMT, GAMT and PRMT) with HFHC diet for 52 weeks. (B) Levels of glycine, a substrate for GNMT, were decreased (p< 0.01) while the product sarcosine did not change between chow and HFHC group. (C) The gene expression of Gnmt , the most abundant methyltranserase in the liver, decreased significantly but only approached significance at the protein level (p = 0.06). (D) Levels of PE, the substrate for PEMT, was significantly reduced (p< 0.01) while PC trended down, resulting in a significant PC/PE ratio (p< 0.01), which suggests increase in PEMT activity There were no significant changes in the concentrations of guanidinoacetate and creatine, the substrate and product for GAMT, respectively. (E) The methylated products of PRMT activity, MMA and ADMA, were decreased significantly (p< 0.01 and p< 0.05) while the decrease in <t>SDMA</t> approached significance (p = 0.07). (F) The gene expression of Prmt1 , mainly responsible for the methylation of MMA and ADMA, decreased (p< 0.01) but the protein levels of PRMT1 increased significantly (p< 0.05). (G) Circulating ADMA was increased toward significance (p = 0.06), suggesting increased export to the circulation. Data are represented as mean ± SEM. Legend: arginine (Arg); asymmetric <t>dimethylarginine</t> (ADMA); creatine (Crea); glycine (Gly); glycine N-methyltransferase (GNMT); guanidinoacetate (GAA); guanidinoacetate methyltransferase (GAMT); homocysteine (Hcy); monomethylarginine (MMA); phosphatidylcholine (PC); phosphatidylethanolamine (PE); phosphatidylethanolamine methyltransferase (PEMT); protein arginine methyltransferase (PRMT); s-adenosylhomocysteine (SAH); s-adenosylmethionine (SAM); sarcosine (Sar); symmetric dimethylarginine (SDMA).
Sdma In Pooled Charcoal Stripped Mongrel Serum, supplied by BioIVT Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IDEXX sdma tm test

Sdma Tm Test, supplied by IDEXX, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IDEXX high-throughput immunoassay idexx sdma test

High Throughput Immunoassay Idexx Sdma Test, supplied by IDEXX, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IDEXX high-throughput immunoassay sdma test

High Throughput Immunoassay Sdma Test, supplied by IDEXX, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IDEXX symmetric dimethylarginine sdma

Symmetric Dimethylarginine Sdma, supplied by IDEXX, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IDEXX idexx sdma test
(A) <t>The</t> <t>IDEXX</t> <t>SDMA</t> Test. (B) The DLD SDMA ELISA method. Solid line represents best fit linear model; shading represents 95% confidence interval around the line. Dashed line is the line of equality. Outliers are represented by *.
Idexx Sdma Test, supplied by IDEXX, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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IDEXX sdma concentration measurement
(A) <t>The</t> <t>IDEXX</t> <t>SDMA</t> Test. (B) The DLD SDMA ELISA method. Solid line represents best fit linear model; shading represents 95% confidence interval around the line. Dashed line is the line of equality. Outliers are represented by *.
Sdma Concentration Measurement, supplied by IDEXX, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Enzo Biochem sdma
(A) <t>The</t> <t>IDEXX</t> <t>SDMA</t> Test. (B) The DLD SDMA ELISA method. Solid line represents best fit linear model; shading represents 95% confidence interval around the line. Dashed line is the line of equality. Outliers are represented by *.
Sdma, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Platelet reactivity, sP-selectin and endothelial biomarkers in patients on DAPT with ticagrelor and clopidogrel stratified by diabetes status

Journal: Cardiovascular Diabetology

Article Title: Endothelial biomarkers and platelet reactivity on ticagrelor versus clopidogrel in patients after acute coronary syndrome with and without concomitant type 2 diabetes: a preliminary observational study

doi: 10.1186/s12933-022-01685-4

Figure Lengend Snippet: Platelet reactivity, sP-selectin and endothelial biomarkers in patients on DAPT with ticagrelor and clopidogrel stratified by diabetes status

Article Snippet: Additionally, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) were measured in a subgroup of the study subjects by ELISA (Immundiagnostik AG, Bernsheim, Germany).

Techniques:

(A) Heat map representation of substrates and methylated products of major SAM-derived transmethylation reactions (PEMT, GNMT, GAMT and PRMT) with HFHC diet for 52 weeks. (B) Levels of glycine, a substrate for GNMT, were decreased (p< 0.01) while the product sarcosine did not change between chow and HFHC group. (C) The gene expression of Gnmt , the most abundant methyltranserase in the liver, decreased significantly but only approached significance at the protein level (p = 0.06). (D) Levels of PE, the substrate for PEMT, was significantly reduced (p< 0.01) while PC trended down, resulting in a significant PC/PE ratio (p< 0.01), which suggests increase in PEMT activity There were no significant changes in the concentrations of guanidinoacetate and creatine, the substrate and product for GAMT, respectively. (E) The methylated products of PRMT activity, MMA and ADMA, were decreased significantly (p< 0.01 and p< 0.05) while the decrease in SDMA approached significance (p = 0.07). (F) The gene expression of Prmt1 , mainly responsible for the methylation of MMA and ADMA, decreased (p< 0.01) but the protein levels of PRMT1 increased significantly (p< 0.05). (G) Circulating ADMA was increased toward significance (p = 0.06), suggesting increased export to the circulation. Data are represented as mean ± SEM. Legend: arginine (Arg); asymmetric dimethylarginine (ADMA); creatine (Crea); glycine (Gly); glycine N-methyltransferase (GNMT); guanidinoacetate (GAA); guanidinoacetate methyltransferase (GAMT); homocysteine (Hcy); monomethylarginine (MMA); phosphatidylcholine (PC); phosphatidylethanolamine (PE); phosphatidylethanolamine methyltransferase (PEMT); protein arginine methyltransferase (PRMT); s-adenosylhomocysteine (SAH); s-adenosylmethionine (SAM); sarcosine (Sar); symmetric dimethylarginine (SDMA).

Journal: PLoS ONE

Article Title: Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease

doi: 10.1371/journal.pone.0136822

Figure Lengend Snippet: (A) Heat map representation of substrates and methylated products of major SAM-derived transmethylation reactions (PEMT, GNMT, GAMT and PRMT) with HFHC diet for 52 weeks. (B) Levels of glycine, a substrate for GNMT, were decreased (p< 0.01) while the product sarcosine did not change between chow and HFHC group. (C) The gene expression of Gnmt , the most abundant methyltranserase in the liver, decreased significantly but only approached significance at the protein level (p = 0.06). (D) Levels of PE, the substrate for PEMT, was significantly reduced (p< 0.01) while PC trended down, resulting in a significant PC/PE ratio (p< 0.01), which suggests increase in PEMT activity There were no significant changes in the concentrations of guanidinoacetate and creatine, the substrate and product for GAMT, respectively. (E) The methylated products of PRMT activity, MMA and ADMA, were decreased significantly (p< 0.01 and p< 0.05) while the decrease in SDMA approached significance (p = 0.07). (F) The gene expression of Prmt1 , mainly responsible for the methylation of MMA and ADMA, decreased (p< 0.01) but the protein levels of PRMT1 increased significantly (p< 0.05). (G) Circulating ADMA was increased toward significance (p = 0.06), suggesting increased export to the circulation. Data are represented as mean ± SEM. Legend: arginine (Arg); asymmetric dimethylarginine (ADMA); creatine (Crea); glycine (Gly); glycine N-methyltransferase (GNMT); guanidinoacetate (GAA); guanidinoacetate methyltransferase (GAMT); homocysteine (Hcy); monomethylarginine (MMA); phosphatidylcholine (PC); phosphatidylethanolamine (PE); phosphatidylethanolamine methyltransferase (PEMT); protein arginine methyltransferase (PRMT); s-adenosylhomocysteine (SAH); s-adenosylmethionine (SAM); sarcosine (Sar); symmetric dimethylarginine (SDMA).

Article Snippet: Asymmetric-dimethylarginine (ADMA) and symmetric-dimethylarginine (SDMA) were purchased from Axxora LLC (San Diego, CA).

Techniques: Methylation, Derivative Assay, Expressing, Activity Assay

Journal: Journal of Veterinary Internal Medicine

Article Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM‐CA CONGRESS

doi: 10.1111/jvim.15372

Figure Lengend Snippet:

Article Snippet: Serum symmetric dimethylarginine (SDMA, IDEXX SDMA TM Test) was measured as a novel functional renal biomarker.

Techniques: Biomarker Discovery, Clinical Proteomics, Activity Assay, Concentration Assay, Comparison, Computed Tomography, Micro-CT, Enzyme-linked Immunosorbent Assay, Expressing, Adjuvant, Electrotransfer, Histopathology, Virus, Filtration, In Vitro, Membrane, Transplantation Assay, Control, Functional Assay

(A) The IDEXX SDMA Test. (B) The DLD SDMA ELISA method. Solid line represents best fit linear model; shading represents 95% confidence interval around the line. Dashed line is the line of equality. Outliers are represented by *.

Journal: PLoS ONE

Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum

doi: 10.1371/journal.pone.0205030

Figure Lengend Snippet: (A) The IDEXX SDMA Test. (B) The DLD SDMA ELISA method. Solid line represents best fit linear model; shading represents 95% confidence interval around the line. Dashed line is the line of equality. Outliers are represented by *.

Article Snippet: Accuracy , IDEXX SDMA Test , Overall , 1.06 (1.03, 1.08) , 0.34 (-0.25, 0.92) , 0.99.

Techniques: Enzyme-linked Immunosorbent Assay

Slopes and intercepts with 95% confidence intervals for the best fit linear models determined for all samples and for canine and feline samples individually.

Journal: PLoS ONE

Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum

doi: 10.1371/journal.pone.0205030

Figure Lengend Snippet: Slopes and intercepts with 95% confidence intervals for the best fit linear models determined for all samples and for canine and feline samples individually.

Article Snippet: Accuracy , IDEXX SDMA Test , Overall , 1.06 (1.03, 1.08) , 0.34 (-0.25, 0.92) , 0.99.

Techniques: Enzyme-linked Immunosorbent Assay

(A) The IDEXX SDMA Test. (B) The DLD SDMA ELISA method. Solid line represents best fit linear model; shading represents 95% confidence interval around the line. Dashed line is the line of equality. Outliers are represented by *.

Journal: PLoS ONE

Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum

doi: 10.1371/journal.pone.0205030

Figure Lengend Snippet: (A) The IDEXX SDMA Test. (B) The DLD SDMA ELISA method. Solid line represents best fit linear model; shading represents 95% confidence interval around the line. Dashed line is the line of equality. Outliers are represented by *.

Article Snippet: Accuracy , IDEXX SDMA Test , Overall , 1.06 (1.03, 1.08) , 0.34 (-0.25, 0.92) , 0.99.

Techniques: Enzyme-linked Immunosorbent Assay

Systematic bias calculated from fit lines of  IDEXX   SDMA Test  and DLD ELISA SDMA compared to LC-MS over a clinically relevant range of SDMA concentrations.

Journal: PLoS ONE

Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum

doi: 10.1371/journal.pone.0205030

Figure Lengend Snippet: Systematic bias calculated from fit lines of IDEXX SDMA Test and DLD ELISA SDMA compared to LC-MS over a clinically relevant range of SDMA concentrations.

Article Snippet: Accuracy , IDEXX SDMA Test , Overall , 1.06 (1.03, 1.08) , 0.34 (-0.25, 0.92) , 0.99.

Techniques: Enzyme-linked Immunosorbent Assay

(A) The IDEXX SDMA Test–Feline sample, 31.6 μg/dL (LC-MS). (B) The DLD SDMA ELISA method–Feline sample, 31.6 μg/dL (LC-MS). (C) The IDEXX SDMA Test–Canine sample, 11.8 μg/dL (LC-MS). (D) The DLD SDMA ELISA method–Canine sample, 11.8 μg/dL (LC-MS). Outliers are represented by *.

Journal: PLoS ONE

Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum

doi: 10.1371/journal.pone.0205030

Figure Lengend Snippet: (A) The IDEXX SDMA Test–Feline sample, 31.6 μg/dL (LC-MS). (B) The DLD SDMA ELISA method–Feline sample, 31.6 μg/dL (LC-MS). (C) The IDEXX SDMA Test–Canine sample, 11.8 μg/dL (LC-MS). (D) The DLD SDMA ELISA method–Canine sample, 11.8 μg/dL (LC-MS). Outliers are represented by *.

Article Snippet: Accuracy , IDEXX SDMA Test , Overall , 1.06 (1.03, 1.08) , 0.34 (-0.25, 0.92) , 0.99.

Techniques: Liquid Chromatography with Mass Spectroscopy, Enzyme-linked Immunosorbent Assay

Variation by assay for each pooled serum sample.

Journal: PLoS ONE

Article Title: Comparative performance of IDEXX SDMA Test and the DLD SDMA ELISA for the measurement of SDMA in canine and feline serum

doi: 10.1371/journal.pone.0205030

Figure Lengend Snippet: Variation by assay for each pooled serum sample.

Article Snippet: Accuracy , IDEXX SDMA Test , Overall , 1.06 (1.03, 1.08) , 0.34 (-0.25, 0.92) , 0.99.

Techniques: Standard Deviation, Enzyme-linked Immunosorbent Assay