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European Collection of Authenticated Cell Cultures
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iCell Bioscience Inc
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National Centre for Cell Science
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Verlag GmbH
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Charles River Laboratories
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The SCC9 GFP cell line is transformed from SCC9 cell, expressing the GFP gene. The cell constitutively express GFP.
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The SCC9 Luciferase cell line is transformed from SCC9 cell, expressing the firefly luciferase gene. The cell constitutively express Luciferase.
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Image Search Results
Journal: bioRxiv
Article Title: Interplay of YEATS2 and GCDH mediates histone crotonylation and drives EMT in head and neck cancer
doi: 10.1101/2024.09.24.614679
Figure Lengend Snippet: (A) qRT-PCR results showing decrease in SPARC expression on GCDH-knockdown in BICR10 cells (B) Immunoblot showing the reduced expression of SPARC upon GCDH-knockdown in SCC9 cells. (C) Decrease in H3K27Cr levels on SPARC promoter in sh GCDH BICR10 cells. (D) Immunoblot showing the reduced expression of GCDH on SP1-knockdown in BICR10 cells. (E) Plot showing SP1 binding on GCDH promoter in SP1-ChIP assay in BICR10. (F) IF images showing reduced nuclear localization in sh YEATS2 BICR10 cells. Scale bar, μm. (G) Immunoblot depicting decreased SPARC expression on SP1 knockdown and its subsequent rescue upon YEATS2 and GCDH overexpression in sh SP1 BICR10 cells. Error bars, mean ± SEM; two-tailed t test, ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, n = 3 biological replicates.
Article Snippet: Human head and neck cancer cell lines BICR10 and
Techniques: Quantitative RT-PCR, Expressing, Knockdown, Western Blot, Binding Assay, Over Expression, Two Tailed Test