rsem software Search Results


rsem software  (Broad Institute Inc)
90
Broad Institute Inc rsem software
MTH1 inhibition <t>retards</t> <t>mesothelioma</t> progression in vivo. (A) <t>RSEM</t> data of RNA-seq analysis retrieved by the TCGA biobank were analyzed using the UALCAN portal. Kaplan-Meier plot correlating NUDT1 gene expression with mesothelioma patients’ survival (high MTH1, n = 21; low/medium MTH1, n = 64). P value was obtained upon log-rank test. (B–E) Human mesothelioma tumors were created upon s.c. injection of 2 × 106 ZL34 or MSTO-211H cells in NOD.SCID mice. TH1579 administration commenced once tumors became 200 mm3. Mice received vehicle or TH1579 (90 mg/kg body weight) 2 times per day, every 2 days. Tumor size was measured by a digital caliper (B and D). On the day of sacrifice, mesothelioma tumors were excised and weighed (C and E). Data presented as mean ± SEM. ZL34: vehicle and TH1579, n = 17 mice each. MSTO-211: vehicle, n = 6 mice; TH1579, n = 7 mice. *P < 0.05 compared with vehicle by 2-tailed Students’ t test. (F and G) AB1 and AE17 cells were intrapleurally injected into syngeneic BALB/c and C57BL/6 mice, respectively, and animals were treated as above. Fourteen days later, mice were sacrificed and mesothelioma tumors were excised and weighed (F) and pleural fluid was retrieved and quantified (G). Data presented as mean ± SEM. AB1: vehicle, n = 8 mice; TH1579, n = 10 mice. AE17: vehicle, n = 10 mice; TH1579, n = 11 mice. *P < 0.05 compared with vehicle by 2-tailed Students’ t test.
Rsem Software, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rsem+software/rsem+software/pmc07406306-556-8-21
Average 90 stars, based on 1 article reviews
rsem software - by Bioz Stars, 2026-11
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transcriptome expression quantification software rsem v 2 15  (Unigene)
86
Unigene transcriptome expression quantification software rsem v 2 15
MTH1 inhibition <t>retards</t> <t>mesothelioma</t> progression in vivo. (A) <t>RSEM</t> data of RNA-seq analysis retrieved by the TCGA biobank were analyzed using the UALCAN portal. Kaplan-Meier plot correlating NUDT1 gene expression with mesothelioma patients’ survival (high MTH1, n = 21; low/medium MTH1, n = 64). P value was obtained upon log-rank test. (B–E) Human mesothelioma tumors were created upon s.c. injection of 2 × 106 ZL34 or MSTO-211H cells in NOD.SCID mice. TH1579 administration commenced once tumors became 200 mm3. Mice received vehicle or TH1579 (90 mg/kg body weight) 2 times per day, every 2 days. Tumor size was measured by a digital caliper (B and D). On the day of sacrifice, mesothelioma tumors were excised and weighed (C and E). Data presented as mean ± SEM. ZL34: vehicle and TH1579, n = 17 mice each. MSTO-211: vehicle, n = 6 mice; TH1579, n = 7 mice. *P < 0.05 compared with vehicle by 2-tailed Students’ t test. (F and G) AB1 and AE17 cells were intrapleurally injected into syngeneic BALB/c and C57BL/6 mice, respectively, and animals were treated as above. Fourteen days later, mice were sacrificed and mesothelioma tumors were excised and weighed (F) and pleural fluid was retrieved and quantified (G). Data presented as mean ± SEM. AB1: vehicle, n = 8 mice; TH1579, n = 10 mice. AE17: vehicle, n = 10 mice; TH1579, n = 11 mice. *P < 0.05 compared with vehicle by 2-tailed Students’ t test.
Transcriptome Expression Quantification Software Rsem V 2 15, supplied by Unigene, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rsem+software/15+2+expression+quantification+rsem+software+transcriptome+v/pmc12443844-77-2-10
Average 86 stars, based on 1 article reviews
transcriptome expression quantification software rsem v 2 15 - by Bioz Stars, 2026-11
86/100 stars
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Image Search Results


MTH1 inhibition retards mesothelioma progression in vivo. (A) RSEM data of RNA-seq analysis retrieved by the TCGA biobank were analyzed using the UALCAN portal. Kaplan-Meier plot correlating NUDT1 gene expression with mesothelioma patients’ survival (high MTH1, n = 21; low/medium MTH1, n = 64). P value was obtained upon log-rank test. (B–E) Human mesothelioma tumors were created upon s.c. injection of 2 × 106 ZL34 or MSTO-211H cells in NOD.SCID mice. TH1579 administration commenced once tumors became 200 mm3. Mice received vehicle or TH1579 (90 mg/kg body weight) 2 times per day, every 2 days. Tumor size was measured by a digital caliper (B and D). On the day of sacrifice, mesothelioma tumors were excised and weighed (C and E). Data presented as mean ± SEM. ZL34: vehicle and TH1579, n = 17 mice each. MSTO-211: vehicle, n = 6 mice; TH1579, n = 7 mice. *P < 0.05 compared with vehicle by 2-tailed Students’ t test. (F and G) AB1 and AE17 cells were intrapleurally injected into syngeneic BALB/c and C57BL/6 mice, respectively, and animals were treated as above. Fourteen days later, mice were sacrificed and mesothelioma tumors were excised and weighed (F) and pleural fluid was retrieved and quantified (G). Data presented as mean ± SEM. AB1: vehicle, n = 8 mice; TH1579, n = 10 mice. AE17: vehicle, n = 10 mice; TH1579, n = 11 mice. *P < 0.05 compared with vehicle by 2-tailed Students’ t test.

Journal: JCI Insight

Article Title: MTH1 favors mesothelioma progression and mediates paracrine rescue of bystander endothelium from oxidative damage

doi: 10.1172/jci.insight.134885

Figure Lengend Snippet: MTH1 inhibition retards mesothelioma progression in vivo. (A) RSEM data of RNA-seq analysis retrieved by the TCGA biobank were analyzed using the UALCAN portal. Kaplan-Meier plot correlating NUDT1 gene expression with mesothelioma patients’ survival (high MTH1, n = 21; low/medium MTH1, n = 64). P value was obtained upon log-rank test. (B–E) Human mesothelioma tumors were created upon s.c. injection of 2 × 106 ZL34 or MSTO-211H cells in NOD.SCID mice. TH1579 administration commenced once tumors became 200 mm3. Mice received vehicle or TH1579 (90 mg/kg body weight) 2 times per day, every 2 days. Tumor size was measured by a digital caliper (B and D). On the day of sacrifice, mesothelioma tumors were excised and weighed (C and E). Data presented as mean ± SEM. ZL34: vehicle and TH1579, n = 17 mice each. MSTO-211: vehicle, n = 6 mice; TH1579, n = 7 mice. *P < 0.05 compared with vehicle by 2-tailed Students’ t test. (F and G) AB1 and AE17 cells were intrapleurally injected into syngeneic BALB/c and C57BL/6 mice, respectively, and animals were treated as above. Fourteen days later, mice were sacrificed and mesothelioma tumors were excised and weighed (F) and pleural fluid was retrieved and quantified (G). Data presented as mean ± SEM. AB1: vehicle, n = 8 mice; TH1579, n = 10 mice. AE17: vehicle, n = 10 mice; TH1579, n = 11 mice. *P < 0.05 compared with vehicle by 2-tailed Students’ t test.

Article Snippet: Mesothelioma gene-level raw expression RNA-seq data produced by RSEM software ( 43 ) (MESO.uncv2.mRNaseq_raw_counts.txt), along with clinical information, were downloaded from Broad Institute TCGA Genome Data Analysis Center Firehose ( https://gdac.broadinstitute.org/ ) ( 44 ).

Techniques: Inhibition, In Vivo, RNA Sequencing, Gene Expression, Injection