rotigotine Search Results


d3 rotigotine  (Thermo Fisher)
93
Thermo Fisher d3 rotigotine
D3 Rotigotine, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/d3 rotigotine/product/Thermo Fisher
Average 93 stars, based on 1 article reviews
d3 rotigotine - by Bioz Stars, 2026-04
93/100 stars
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rotigotine  (MedChemExpress)
93
MedChemExpress rotigotine
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rotigotine, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rotigotine/product/MedChemExpress
Average 93 stars, based on 1 article reviews
rotigotine - by Bioz Stars, 2026-04
93/100 stars
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rotigotine  (TargetMol)
91
TargetMol rotigotine
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rotigotine, supplied by TargetMol, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rotigotine/product/TargetMol
Average 91 stars, based on 1 article reviews
rotigotine - by Bioz Stars, 2026-04
91/100 stars
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rtg  (Selleck Chemicals)
88
Selleck Chemicals rtg
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rtg, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rtg/product/Selleck Chemicals
Average 88 stars, based on 1 article reviews
rtg - by Bioz Stars, 2026-04
88/100 stars
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rotigotine transdermal patch  (Schwarz Pharma)
90
Schwarz Pharma rotigotine transdermal patch
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rotigotine Transdermal Patch, supplied by Schwarz Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rotigotine transdermal patch/product/Schwarz Pharma
Average 90 stars, based on 1 article reviews
rotigotine transdermal patch - by Bioz Stars, 2026-04
90/100 stars
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rotigotine  (Schwarz Pharma)
90
Schwarz Pharma rotigotine
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rotigotine, supplied by Schwarz Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rotigotine/product/Schwarz Pharma
Average 90 stars, based on 1 article reviews
rotigotine - by Bioz Stars, 2026-04
90/100 stars
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rotigotine neupro  (Schwarz Pharma)
90
Schwarz Pharma rotigotine neupro
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rotigotine Neupro, supplied by Schwarz Pharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rotigotine neupro/product/Schwarz Pharma
Average 90 stars, based on 1 article reviews
rotigotine neupro - by Bioz Stars, 2026-04
90/100 stars
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rotigotine  (Nacalai)
90
Nacalai rotigotine
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rotigotine, supplied by Nacalai, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rotigotine/product/Nacalai
Average 90 stars, based on 1 article reviews
rotigotine - by Bioz Stars, 2026-04
90/100 stars
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rotigotine  (Kolster Methods)
90
Kolster Methods rotigotine
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rotigotine, supplied by Kolster Methods, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rotigotine/product/Kolster Methods
Average 90 stars, based on 1 article reviews
rotigotine - by Bioz Stars, 2026-04
90/100 stars
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rotigotine  (Wolters Kluwer Health)
90
Wolters Kluwer Health rotigotine
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rotigotine, supplied by Wolters Kluwer Health, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rotigotine/product/Wolters Kluwer Health
Average 90 stars, based on 1 article reviews
rotigotine - by Bioz Stars, 2026-04
90/100 stars
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poxylated rotigotine  (Serina Therapeutics)
90
Serina Therapeutics poxylated rotigotine
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Poxylated Rotigotine, supplied by Serina Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/poxylated rotigotine/product/Serina Therapeutics
Average 90 stars, based on 1 article reviews
poxylated rotigotine - by Bioz Stars, 2026-04
90/100 stars
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rotigotine  (UCB SA Inc)
90
UCB SA Inc rotigotine
Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and <t>rotigotine</t> (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).
Rotigotine, supplied by UCB SA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rotigotine/product/UCB SA Inc
Average 90 stars, based on 1 article reviews
rotigotine - by Bioz Stars, 2026-04
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Image Search Results


Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and rotigotine (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).

Journal: Frontiers in Cellular and Infection Microbiology

Article Title: Screening of neurotransmitter receptor modulators reveals novel inhibitors of influenza virus replication

doi: 10.3389/fcimb.2025.1562650

Figure Lengend Snippet: Kinetic curves illustrating the toxicity and antiviral activity of the identified compounds in U937 cells. The compounds tested for drug toxicity and antiviral activity were isoxsuprine (A) , ciproxifan (B) , and rotigotine (C) . The U937 cells were seeded in 96-well plates at a density of 1 × 10^6 cells/mL in complete medium and then infected with A/Puerto Rico/8/1934 (H1N1) virus at a multiplicity of infection (MOI) of 0.05. Structures of the three compounds are shown in each panel. The antiviral activity of the candidate compounds was measured by assessing the inhibitory rate of neuraminidase (NA) activity in the supernatant collected from each treatment group. At the same time, the cytotoxicity of these compounds was evaluated in uninfected U937 cells using a cell viability assay. The data presented represent the results from three independent experiments, expressed as mean ± Standard Error of the Mean (SEM). The CC50 and IC50 values were calculated using GraphPad Prism software (version 8.0).

Article Snippet: We selected three hit compounds, isoxsuprine, ciproxifan, and rotigotine, for further in vitro and in vivo antiviral efficacy studies and purchased them from MedChemExpress Co., Ltd. (Shanghai, China).

Techniques: Activity Assay, Infection, Virus, Viability Assay, Software

Broad-spectrum antiviral effects of the three selected compounds against different strains of the influenza virus. compounds tested for broad-spectrum antiviral effects were isoxsuprine (A) , ciproxifan (B) , and rotigotine (C) . The cells used for H1N1 PR8, H1N1 H274Y, and H3N2 infections were A549 cells, while MDCK cells were used for IBV infection. The cells were trypsinized and resuspended for 24 h before infection. They were then seeded in 96-well plates at 20,000 cells per well for A549 cells and 15,000 cells per well for MDCK cells. Once the cells reached approximately 80% confluence, they were infected with 0.1 MOI of the respective viruses in the presence of varying concentrations of the compounds. After 48 h of incubation at 37°C, supernatants were collected, and the viral inhibition rate was determined using a neuraminidase (NA) activity assay. The data presented represent results from three independent experiments (mean ± SEM). The IC50 values were determined using GraphPad Prism software (version 8.0).

Journal: Frontiers in Cellular and Infection Microbiology

Article Title: Screening of neurotransmitter receptor modulators reveals novel inhibitors of influenza virus replication

doi: 10.3389/fcimb.2025.1562650

Figure Lengend Snippet: Broad-spectrum antiviral effects of the three selected compounds against different strains of the influenza virus. compounds tested for broad-spectrum antiviral effects were isoxsuprine (A) , ciproxifan (B) , and rotigotine (C) . The cells used for H1N1 PR8, H1N1 H274Y, and H3N2 infections were A549 cells, while MDCK cells were used for IBV infection. The cells were trypsinized and resuspended for 24 h before infection. They were then seeded in 96-well plates at 20,000 cells per well for A549 cells and 15,000 cells per well for MDCK cells. Once the cells reached approximately 80% confluence, they were infected with 0.1 MOI of the respective viruses in the presence of varying concentrations of the compounds. After 48 h of incubation at 37°C, supernatants were collected, and the viral inhibition rate was determined using a neuraminidase (NA) activity assay. The data presented represent results from three independent experiments (mean ± SEM). The IC50 values were determined using GraphPad Prism software (version 8.0).

Article Snippet: We selected three hit compounds, isoxsuprine, ciproxifan, and rotigotine, for further in vitro and in vivo antiviral efficacy studies and purchased them from MedChemExpress Co., Ltd. (Shanghai, China).

Techniques: Virus, Infection, Incubation, Inhibition, Activity Assay, Software