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Image Search Results
Journal: Frontiers in Immunology
Article Title: FAM20A : a potential diagnostic biomarker for lung squamous cell carcinoma
doi: 10.3389/fimmu.2024.1424197
Figure Lengend Snippet: Expression Levels of FAM20A and FAM20C in LUSC. (A) FAM20A expression across various cancers, as sourced from the GTEx database. (B) FAM20C expression across different cancers, derived from the GTEx database. (C) FAM20A expression in 33 cancer types. (D) FAM20C expression in 33 cancer types. (E) Comparison of FAM20A expression in tumor versus normal samples. (F) Differential expression of FAM20C in tumor samples. (G) Box plots comparing FAM20A , FAM20B , and FAM20C expression in patients with and without LUSC. (H) Expression differences of FAM20A , FAM20B , and FAM20C between LUSC samples and matched non-cancerous samples. (I) ROC curve analysis of FAM20A , FAM20B , and FAM20C in normal versus LUSC samples from the TCGA database. (J) qRT-PCR analysis for FAM20A and FAM20C . (K) Western blot results for FAM20A and FAM20C. (L) Immunohistochemistry (IHC) analysis of FAM20A and FAM20C. Significance levels indicated as * P <0.05, ** P <0.01, *** P <0.001. LUSC, Lung squamous cell carcinoma; Fam20A, Family with Sequence Similarity 20, Member A; FAM20B, Family with Sequence Similarity 20, Member B; FAM20C, Family with Sequence Similarity 20, Member C; ACC, Adrenocortical carcinoma; BLCA, Bladder urothelial carcinoma; BRCA, Breast invasive carcinoma; CESC, Cervical squamous cell carcinoma and endocervical adenocarcinoma; CHOL, Cholangiocarcinoma; COAD, Colon adenocarcinoma; DLBC, Lymphoid neoplasm diffuse large B-cell lymphoma; ESCA, Esophageal carcinoma; GBM, Glioblastoma multiforme; HNSC, Head and neck squamous cell carcinoma; KICH, Kidney chromophobe; KIRC, Kidney renal clear cell carcinoma; KIRP, Kidney renal papillary cell carcinoma; LAML, Acute myeloid leukemia; LGG, Brain lower grade glioma; LIHC, Liver hepatocellular carcinoma; LUAD, Lung adenocarcinoma; MESO, Mesothelioma; OV, Ovarian serous cystadenocarcinoma; PAAD, Pancreatic adenocarcinoma; PCPG, Pheochromocytoma and paraganglioma; PRAD, Prostate adenocarcinoma; READ, Rectum adenocarcinoma; SARC, Sarcoma; SKCM, Skin cutaneous melanoma; STAD, Stomach adenocarcinoma; TGCT, Testicular germ cell tumors; THCA, Thyroid carcinoma; THYM, Thymoma; UCEC, Uterine corpus endometrial carcinoma; UCS, Uterine carcinosarcoma; UVM, Uveal melanoma. ns: not significant difference.
Article Snippet: After blocking with 5% BSA, the membrane was incubated with polyclonal anti-FAM20A (1:1000, Cat. No. 25258–1-AP, Proteintech, USA), and
Techniques: Expressing, Derivative Assay, Comparison, Quantitative Proteomics, Quantitative RT-PCR, Western Blot, Immunohistochemistry, Sequencing
Journal: Frontiers in Immunology
Article Title: FAM20A : a potential diagnostic biomarker for lung squamous cell carcinoma
doi: 10.3389/fimmu.2024.1424197
Figure Lengend Snippet: Survival Analysis in LUSC Based on FAM20A and FAM20C. Utilizing the GEPIA2 tool, overall survival (OS), disease-specific survival (DSS), and progression-free interval (PFI) in LUSC were analyzed in relation to the expression of FAM20A and FAM20C, with survival plots provided. Significance levels indicated as * P <0.05, ** P <0.01, *** P <0.001. LUSC, Lung squamous cell carcinoma; FAM20A, Family with Sequence Similarity 20, Member A; FAM20C, Family with Sequence Similarity 20, Member C; GEPIA2, Gene Expression Profiling Interactive Analysis 2; OS, Overall survival; DSS, Disease-specific survival; PFI, Progression-free interval.
Article Snippet: After blocking with 5% BSA, the membrane was incubated with polyclonal anti-FAM20A (1:1000, Cat. No. 25258–1-AP, Proteintech, USA), and
Techniques: Expressing, Sequencing, Gene Expression
Journal: Frontiers in Immunology
Article Title: FAM20A : a potential diagnostic biomarker for lung squamous cell carcinoma
doi: 10.3389/fimmu.2024.1424197
Figure Lengend Snippet: Association of FAM20A and FAM20C levels with Clinical Pathological Traits in LUSC. (A) Overall survival, (B) Disease specific survival and (C) Progress Free interval of FAM20A mRNA levels. (D) Overall survival, (E) Disease specific survival and (F) Progress Free interval of FAM20C mRNA levels. Significant levels indicated as * P <0.05, ** P <0.01, *** P <0.001. LUSC, Lung squamous cell carcinoma; Fam20A, Family with Squance Similarity 20, member A; Fam20C, Family with Squance Similarity 20, member C.
Article Snippet: After blocking with 5% BSA, the membrane was incubated with polyclonal anti-FAM20A (1:1000, Cat. No. 25258–1-AP, Proteintech, USA), and
Techniques: