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Image Search Results
Journal: Cells
Article Title: Mutant KRAS-Associated Proteome Is Mainly Controlled by Exogenous Factors
doi: 10.3390/cells11131988
Figure Lengend Snippet: HCT116 and LS174T differentially expressed proteins, upon culture with rhTGFβ1-activated fibroblasts conditioned medium. Significantly up and downregulated proteins in HCT116 ( a ) and LS174T ( b ) siCTRL cells cultured with FibCM (siCTRL_FibCM vs. siCTRL_ctrlCM). Protein lists are organized according to the abundance ratio and common proteins to HCT116 and LS174T cells are highlighted in bold (TGFBI, COL1A1, FN1). GO and KEGG pathways analysis of up and downregulated proteins in HCT116 ( c ) and LS174T ( d ). The enrichment score was calculated by—log p -value.
Article Snippet: “Normal-like” fibroblasts were cultured in serum-free DMEM (supplemented only with 1% penicillin/streptomycin) and “activated-fibroblasts” were cultured in the same medium supplemented with 10 ng/mL of
Techniques: Cell Culture