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Image Search Results
Journal: medRxiv
Article Title: Population-specific polygenic risk for Alzheimer’s disease is associated with Mini-Mental State Examination-based cognitive decline in a Japanese cohort
doi: 10.64898/2026.03.26.26349120
Figure Lengend Snippet: A Study design and participant selection. Information of the Arao cohort included MMSE score, diagnostic status, genome-wide SNP data, and APOE genotype. Of 1,526 baseline participants, 1,521 with consent for genetic analysis were selected and subjected to principal component analysis (PCA). After quality control, 1,310 participants were retained for PRS construction. Participants with complete data were included in subsequent analyses ( N = 1,301). B Scatter plot of the first and second principal components (PCs) for study participants ( N = 1,521) and the 1000 Genomes project samples ( N = 2,504). Each point represents an individual based on genome-wide SNP data and is colored by population: AFR, African; AMR, Admixed American; EAS, East Asian; SAS, South Asian; EUR, European.
Article Snippet: Curation of SNP data was conducted using a
Techniques: Selection, Diagnostic Assay, Genome Wide, Control