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Image Search Results
Journal: Journal of Inflammation Research
Article Title: Electroacupuncture Inhibits the Early Neuroinflammatory Cascade Triggered by TLR2 in the Prodromal Period of PD
doi: 10.2147/JIR.S585729
Figure Lengend Snippet: EA can inhibit the activation of microglia in the pPD stage mediated by TLR2. ( A ) Western blot detection of TLR2 protein expression in the substantia nigra. ( B ) Western blot detection of MyD88 protein expression in the substantia nigra. ( C ) Western blot detection of p-NF-κB-p65 expression in the substantia nigra. ( D ) Western blot detection of NLRP3 protein expression in the substantia nigra. ( E ) Western blot detection of Caspase-1 protein expression in the substantia nigra. ( F ) Western blot detection of GSDMD protein expression in the substantia nigra. ( G ) Western blot detection of IL-1β protein expression in the substantia nigra. (n=6; compared with the control group, *** P <0.001; compared with the model group, ### P <0.001, ## P <0.01, # P <0.05).
Article Snippet: The membrane was incubated overnight at 4°C with primary antibodies specific to TLR2 (#bs-1019R, Bioss, 1:1000), MyD88 (#bs-1047R, Bioss, 1:1000),
Techniques: Activation Assay, Western Blot, Expressing, Control
Journal: Journal of Inflammation Research
Article Title: Electroacupuncture Inhibits the Early Neuroinflammatory Cascade Triggered by TLR2 in the Prodromal Period of PD
doi: 10.2147/JIR.S585729
Figure Lengend Snippet: EA intervention affects the expression of TLR2 in different regions of pPD, inhibits microglial activation, regulates the TLR2/NF-κB/NLRP3 pathway, and suppresses pyroptosis of microglia.
Article Snippet: The membrane was incubated overnight at 4°C with primary antibodies specific to TLR2 (#bs-1019R, Bioss, 1:1000), MyD88 (#bs-1047R, Bioss, 1:1000),
Techniques: Expressing, Activation Assay
Journal: Acta tropica
Article Title: Echinococcus granulosus promotes bone resorption by increasing osteoclasts differentiation.
doi: 10.1016/j.actatropica.2023.107027
Figure Lengend Snippet: Fig. 1. PSCs promote osteoclast differentiation. (A and B) BMMs were grouped to induce differentiation under different interventions and osteoclast formation was detected by TRAP staining. (C and D) Actin ring formation in response to different stimuli. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs the M-CSF + RANKL group. Data are presented as the mean ± SD of three independent experiments. The scale bar is 500 μm.
Article Snippet: Recombinant mouse M-CSF (#416-ML/CF) and
Techniques: Staining
Journal: Acta tropica
Article Title: Echinococcus granulosus promotes bone resorption by increasing osteoclasts differentiation.
doi: 10.1016/j.actatropica.2023.107027
Figure Lengend Snippet: Fig. 2. PSCs promote the expression of osteoclast-related proteins and genes. (A) BMMs were cultured for 24 h using the same intervention method, total RNA was extracted, and the target gene was detected. (B and C) The expression of target proteins was detected between the groups. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs the M-CSF + RANKL group. #P < 0.05, ##P < 0.01, ###P < 0.001, ####P < 0.0001 vs the M-CSF group. Data are presented as the mean ± SD of three independent experiments.
Article Snippet: Recombinant mouse M-CSF (#416-ML/CF) and
Techniques: Expressing, Cell Culture