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Image Search Results
Journal: Oncologie
Article Title: Exploring the mechanism of genistein in treating hepatocellular carcinoma through network pharmacology and molecular docking
doi: 10.1515/oncologie-2024-0304
Figure Lengend Snippet: Figure 5: Genistein inhibits HCC cell proliferation in vitro. (A) Genistein suppresses HCC cell growth based on both concentration and exposure duration. (B) Genistein suppresses expression of the proliferation marker PCNA based on both concentration and exposure duration. (C) Genistein induces G2/M phase arrest in Huh7 and HepG2 cells. (D) Genistein induces G2/M phase arrest marker Cyclin B1 in Huh7 and HepG2 cells (*p<0.05, **p<0.01, ***p<0.001).
Article Snippet: Reagents used in this study included genistein (purity 99 %; catalog number G6649, Sigma-Aldrich, United States), dimethyl sulfoxide (DMSO; Sigma-Aldrich, United States), and antibodies against PCNA (catalog number 10205-2-AP, diluted 1:3,000 with Beyotime QuickBlock Western blocking buffer),
Techniques: In Vitro, Concentration Assay, Expressing, Marker
Journal: Oncologie
Article Title: Exploring the mechanism of genistein in treating hepatocellular carcinoma through network pharmacology and molecular docking
doi: 10.1515/oncologie-2024-0304
Figure Lengend Snippet: Figure 6: In vivo inhibition of malignant proliferation of HCC by genistein. (A) Tumor volume in mice after treatment. (B) Tumor weight in mice after treatment. (C) Photographs of tumors in mice after treatment. (D) Western Blot detected changes in the G2/M phase arrest marker protein Cyclin B1 in tumor tissues of mice after treatment (*p<0.05, ***p<0.001).
Article Snippet: Reagents used in this study included genistein (purity 99 %; catalog number G6649, Sigma-Aldrich, United States), dimethyl sulfoxide (DMSO; Sigma-Aldrich, United States), and antibodies against PCNA (catalog number 10205-2-AP, diluted 1:3,000 with Beyotime QuickBlock Western blocking buffer),
Techniques: In Vivo, Inhibition, Western Blot, Marker