Journal: Biosensors

Article Title: Review of Label-Free Monitoring of Bacteria: From Challenging Practical Applications to Basic Research Perspectives

doi: 10.3390/bios12040188

Figure Lengend Snippet: Summary of the whole bacteria detecting biosensors. In case of SPR and QCM, the different sensing strategies result in various limit of detection values (LOD). Thus, according to these results, the sensitivity of the biosensors can be improved by some development, for example applying nanoparticles. In general, the assay time is less than 1 h. (* represents label-based biosensors for direct comparison with label-free techniques).

Article Snippet: Quantum dot nanobead-based biosensor * , S. typhimurium , 5 × 10 3 CFU/mL , 10 min , Hu et al. [ ] .

Techniques: Bacteria, Comparison, Detection Assay, Adsorption, Avidin-Biotin Assay, Imaging, SPR Assay, Binding Assay, Amplification, Impedance Spectroscopy, Immunomagnetic Separation, Environmental Sampling

Journal: Journal of Nanobiotechnology

Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives

doi: 10.1186/s12951-024-02408-5

Figure Lengend Snippet: The chronological progression—past, present, and anticipated future—of lymph node (LN) imaging via the medium of drug delivery systems (DDSs). Created with BioRender.com

Article Snippet: Quantum dot-based DDSs may induce the production of reactive oxygen species (ROS) via the release of metal ions, such as the Cd ion, resulting in epigenetic modifications.

Techniques: Imaging

Journal: Journal of Nanobiotechnology

Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives

doi: 10.1186/s12951-024-02408-5

Figure Lengend Snippet: A brief historical overview of lymph node metastasis imaging based on DDSs. DDS drug delivery system, CT computed tomography, LSG lymphoscintigraphy, NP nanoparticle, MRI magnetic resonance imaging, ICG indocyanine green, SLN sentinel lymph node

Article Snippet: Quantum dot-based DDSs may induce the production of reactive oxygen species (ROS) via the release of metal ions, such as the Cd ion, resulting in epigenetic modifications.

Techniques: Imaging, Computed Tomography, Magnetic Resonance Imaging

Journal: Journal of Nanobiotechnology

Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives

doi: 10.1186/s12951-024-02408-5

Figure Lengend Snippet: The targeted lymph node mechanisms of drug delivery systems (DDSs). A By modifying their surface charge, composition, and shape, DDSs possess the capability to elude phagocytosis activity by macrophages. B Benefitting from the EPR effect, DDSs can maintain a persistent presence within metastatic lymph nodes. C Leveraging the use of ligand-coupled NPs, DDSs have the potential to actively home in on targeted lymph nodes. D DDSs, when tailored to a specific size, gain the ability to infiltrate lymphatic vessels in substantial volumes. Created with BioRender.com

Article Snippet: Quantum dot-based DDSs may induce the production of reactive oxygen species (ROS) via the release of metal ions, such as the Cd ion, resulting in epigenetic modifications.

Techniques: Activity Assay

Journal: Journal of Nanobiotechnology

Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives

doi: 10.1186/s12951-024-02408-5

Figure Lengend Snippet: The dual role of drug delivery systems (DDSs) in diagnosis and treatment, demonstrating the application of DDSs in delivering photothermal agents. These agents convert light energy into photoacoustic signals for imaging, while simultaneously releasing thermal energy, derived from light absorption, to annihilate tumor cells. Created with BioRender.com

Article Snippet: Quantum dot-based DDSs may induce the production of reactive oxygen species (ROS) via the release of metal ions, such as the Cd ion, resulting in epigenetic modifications.

Techniques: Biomarker Discovery, Imaging, Derivative Assay

Journal: Journal of Nanobiotechnology

Article Title: Revolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives

doi: 10.1186/s12951-024-02408-5

Figure Lengend Snippet: The potential risks associated with drug delivery systems (DDSs) in the context of lymph node metastasis imaging. Nanoparticle (NP)-based DDSs are not devoid of safety concerns. For instance, DDSs containing Gd may precipitate gadolinium deposition disease, causing symptoms such as fatigue and brain fog. Quantum dot-based DDSs may induce the production of reactive oxygen species (ROS) via the release of metal ions, such as the Cd ion, resulting in epigenetic modifications. Despite its initial status as an ideal, safe coating to mitigate DDS side effects, polyethylene glycol (PEG) might still instigate hypersensitivity reactions. Created with BioRender.com

Article Snippet: Quantum dot-based DDSs may induce the production of reactive oxygen species (ROS) via the release of metal ions, such as the Cd ion, resulting in epigenetic modifications.

Techniques: Imaging