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KEY RESOURCES TABLE

Journal: Cell host & microbe

Article Title: The Landscape of Persistent Viral Genomes in ART Treated SIV, SHIV, and HIV-2 Infections

doi: 10.1016/j.chom.2019.06.005

Figure Lengend Snippet: KEY RESOURCES TABLE

Article Snippet: Software and Algorithms CodonCode Aligner Software CodonCode https://www.codoncode.com/aligner/download.htm CLC Genomics Workbench Qiagen https://www.qiagenbioinformatics.com/products/clc-genomics-workbench/ QuantaSoft Analysis-Pro Bio-Rad http://www.bio-rad.com/en-us/product/qx200-droplet-digital-pcr-system?ID=MPOQQE4VY Clustal W EMBL-EBI http://www.ebi.ac.uk/Tools/msa/clustalw2/ MEGA 7.0 MEGA https://www.megasoftware.net/ Experimental Models: Organisms/Strains Rhesus macaques ( Macaca mulatta ) infected with SIV mac251 Indian origin Animals KIC, Ki6, PZB, DEL5, DEAB, DEKW and DEP0 Rhesus macaques ( Macaca mulatta ) infected with SIV mac251 Indian origin Rh52A Rhesus macaques ( Macaca mulatta ) infected with SIV mac239X Indian origin T028, T154, T158, and T159 Rhesus macaques ( Macaca mulatta ) infected with SIV mac239 Indian origin {"type":"entrez-protein","attrs":{"text":"P27779","term_id":"117639","term_text":"P27779"}} P27779 and {"type":"entrez-protein","attrs":{"text":"P28129","term_id":"139730","term_text":"P28129"}} P28129 Rhesus macaques ( Macaca mulatta ) infected with SHIV SF162P Indian origin MH8, PNP, PZN, and MC4 Oligonucleotides Please refer to Table S1 Open in a separate window KEY RESOURCES TABLE Defective viral genomes predominate in treated SIV mac and HIV-2 infection Significantly more SIV proviruses are intact compared to HIV-1 in treated humans Compared to HIV, clonal sequences and deleted genomes are less frequent in SIV infection An assay to directly enumerate intact SIV genomes was developed

Techniques: Virus, Recombinant, DNA Library Preparation, Cell Isolation, Software, Infection