ptdp 43 Search Results


mouse anti-ptdp43 (ps409/ps410) tip-ptd-m01  (Cosmo Bio USA)
90
Cosmo Bio USA mouse anti-ptdp43 (ps409/ps410) tip-ptd-m01
Mouse Anti Ptdp43 (Ps409/Ps410) Tip Ptd M01, supplied by Cosmo Bio USA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mouse anti-ptdp43 (ps409/ps410) tip-ptd-m01/product/Cosmo Bio USA
Average 90 stars, based on 1 article reviews
mouse anti-ptdp43 (ps409/ps410) tip-ptd-m01 - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier
immunoassays for ptdp–43 and inflammatory markers  (Meso Scale Diagnostics LLC)
90
Meso Scale Diagnostics LLC immunoassays for ptdp–43 and inflammatory markers
Immunoassays For Ptdp–43 And Inflammatory Markers, supplied by Meso Scale Diagnostics LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/immunoassays for ptdp–43 and inflammatory markers/product/Meso Scale Diagnostics LLC
Average 90 stars, based on 1 article reviews
immunoassays for ptdp–43 and inflammatory markers - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier
rab poly fl  (EIAab Inc)
90
EIAab Inc rab poly fl
TDP-43 ELISAs in biofluids from 2008 to 2017
Rab Poly Fl, supplied by EIAab Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rab poly fl/product/EIAab Inc
Average 90 stars, based on 1 article reviews
rab poly fl - by Bioz Stars, 2026-05
90/100 stars
  Buy from Supplier
anti ptdp 43 antibodies  (Affinity Biosciences)
86
Affinity Biosciences anti ptdp 43 antibodies
Chronic cerebral hypoperfusion (CCH) induces cytoplasmic mislocalization of Tar DNA‐binding protein 43 (TDP‐43) and phosphorylated TDP‐43 (pTDP‐43) in the cortex and hippocampus. Immunofluorescence staining was performed on 4 µm paraffin‐embedded brain sections. Sections were labeled with <t>anti‐TDP‐43</t> <t>or</t> <t>anti‐pTDP‐43</t> antibodies (green), NeuroTrace neuronal marker (red), and 4′,6‐diamidino‐2‐phenylindole (DAPI) nuclear stain (blue). Only cytoplasmic colocalization of TDP‐43 or pTDP‐43 with NeuroTrace in yellow is shown. Representative high‐magnification images (60×) demonstrate increased cytoplasmic localization of TDP‐43 and pTDP‐43 in neurons following CCH, compared to sham controls. (A–C) Representative images and quantification of cytoplasmic TDP‐43 expression in the cortex, CA1, and CA3 regions, respectively. (D–F) Corresponding data for pTDP‐43. Quantitative analysis was performed using two‐way analysis of variance (ANOVA), with data presented as mean ± standard error of the mean (SEM). Statistical significance was defined as p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***), and p ≤ 0.0001 (****). Scale bar = 20 µm; n ≥ 3 mice per group. Western blot analysis was conducted on cortical tissue lysates from sham and bilateral common carotid artery stenosis (BCAS) mice ( n = 6 per group), with β‐actin used as a loading control. (G) Representative blots for TDP‐43 and pTDP‐43. (H, I) Present quantification of TDP‐43 and pTDP‐43 protein levels, respectively. Statistical analysis was performed using two‐way ANOVA, with data expressed as mean ± SEM. Significance was defined as p ≤ 0.01 (**).
Anti Ptdp 43 Antibodies, supplied by Affinity Biosciences, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti ptdp 43 antibodies/product/Affinity Biosciences
Average 86 stars, based on 1 article reviews
anti ptdp 43 antibodies - by Bioz Stars, 2026-05
86/100 stars
  Buy from Supplier

Image Search Results


TDP-43 ELISAs in biofluids from 2008 to 2017

Journal: Molecular Neurobiology

Article Title: Towards a TDP-43-Based Biomarker for ALS and FTLD

doi: 10.1007/s12035-018-0947-6

Figure Lengend Snippet: TDP-43 ELISAs in biofluids from 2008 to 2017

Article Snippet: Suarez-Calvet (2014) , Rab poly FL (aa1–261) 10782–2-AP (TDP-43 KE00005 Kit)/ rab poly FL (E9442h EIAab Kit, Wuhan) , Biotinylated mouse mono (aa203–212) 60019–2-Ig, Proteintech/ ab poly pTDP (S409) SAB4200223, Sigma-Aldrich, USA , Streptavidin-conjugated HRP Light unit to concentration Normalized to control sample , FTD FTD C9orf72 FTD GRN CON , 51 10 5 22 , 5.9 (3.6–9.4) ++ 1.5 (1.0–7.2) 0.8 (0.5–5.3) 4.4 (3.2–6.9) , 0.12 (0.02–0.8) 1.6 (0.3–9.7) 2.9 (1.0–8.7) ++ 0.05 (0.0–0.3).

Techniques: Enzyme-linked Immunosorbent Assay, Concentration Assay

Chronic cerebral hypoperfusion (CCH) induces cytoplasmic mislocalization of Tar DNA‐binding protein 43 (TDP‐43) and phosphorylated TDP‐43 (pTDP‐43) in the cortex and hippocampus. Immunofluorescence staining was performed on 4 µm paraffin‐embedded brain sections. Sections were labeled with anti‐TDP‐43 or anti‐pTDP‐43 antibodies (green), NeuroTrace neuronal marker (red), and 4′,6‐diamidino‐2‐phenylindole (DAPI) nuclear stain (blue). Only cytoplasmic colocalization of TDP‐43 or pTDP‐43 with NeuroTrace in yellow is shown. Representative high‐magnification images (60×) demonstrate increased cytoplasmic localization of TDP‐43 and pTDP‐43 in neurons following CCH, compared to sham controls. (A–C) Representative images and quantification of cytoplasmic TDP‐43 expression in the cortex, CA1, and CA3 regions, respectively. (D–F) Corresponding data for pTDP‐43. Quantitative analysis was performed using two‐way analysis of variance (ANOVA), with data presented as mean ± standard error of the mean (SEM). Statistical significance was defined as p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***), and p ≤ 0.0001 (****). Scale bar = 20 µm; n ≥ 3 mice per group. Western blot analysis was conducted on cortical tissue lysates from sham and bilateral common carotid artery stenosis (BCAS) mice ( n = 6 per group), with β‐actin used as a loading control. (G) Representative blots for TDP‐43 and pTDP‐43. (H, I) Present quantification of TDP‐43 and pTDP‐43 protein levels, respectively. Statistical analysis was performed using two‐way ANOVA, with data expressed as mean ± SEM. Significance was defined as p ≤ 0.01 (**).

Journal: Alzheimer's & Dementia

Article Title: Characterizing TDP‐43 involvement in vascular dementia

doi: 10.1002/alz.71196

Figure Lengend Snippet: Chronic cerebral hypoperfusion (CCH) induces cytoplasmic mislocalization of Tar DNA‐binding protein 43 (TDP‐43) and phosphorylated TDP‐43 (pTDP‐43) in the cortex and hippocampus. Immunofluorescence staining was performed on 4 µm paraffin‐embedded brain sections. Sections were labeled with anti‐TDP‐43 or anti‐pTDP‐43 antibodies (green), NeuroTrace neuronal marker (red), and 4′,6‐diamidino‐2‐phenylindole (DAPI) nuclear stain (blue). Only cytoplasmic colocalization of TDP‐43 or pTDP‐43 with NeuroTrace in yellow is shown. Representative high‐magnification images (60×) demonstrate increased cytoplasmic localization of TDP‐43 and pTDP‐43 in neurons following CCH, compared to sham controls. (A–C) Representative images and quantification of cytoplasmic TDP‐43 expression in the cortex, CA1, and CA3 regions, respectively. (D–F) Corresponding data for pTDP‐43. Quantitative analysis was performed using two‐way analysis of variance (ANOVA), with data presented as mean ± standard error of the mean (SEM). Statistical significance was defined as p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***), and p ≤ 0.0001 (****). Scale bar = 20 µm; n ≥ 3 mice per group. Western blot analysis was conducted on cortical tissue lysates from sham and bilateral common carotid artery stenosis (BCAS) mice ( n = 6 per group), with β‐actin used as a loading control. (G) Representative blots for TDP‐43 and pTDP‐43. (H, I) Present quantification of TDP‐43 and pTDP‐43 protein levels, respectively. Statistical analysis was performed using two‐way ANOVA, with data expressed as mean ± SEM. Significance was defined as p ≤ 0.01 (**).

Article Snippet: Sections were blocked (3% horse serum, 0.3% Triton X‐100 in PBS), then incubated overnight at 4°C with anti‐TDP‐43 or anti‐pTDP‐43 antibodies (Affinity Biosciences).

Techniques: Binding Assay, Immunofluorescence, Staining, Labeling, Marker, Expressing, Western Blot, Control

Cytoplasmic mislocalization of Tar DNA‐binding protein 43 (TDP‐43) and the phosphorylated form (pTDP‐43) following 40% oxygen–glucose deprivation (OGD). Immunocytochemistry was performed on SH‐SY5Y cells and primary cortical neurons ( n = 3–4 biological replicates) to assess cytoplasmic redistribution of TDP‐43 and pTDP‐43 in response to 40% OGD. Cells were stained with anti–TDP‐43 or anti–pTDP‐43 (green), anti–βIII‐Tubulin or MAP2 (red), and 4′,6‐diamidino‐2‐phenylindole (DAPI) (blue). Only cytoplasmic colocalization of TDP‐43 or pTDP‐43 with neuronal markers is shown in yellow in merged images. Representative confocal micrographs were acquired at 60× magnification. (A) SH‐SY5Y and (B) primary neuron show cytoplasmic TDP‐43 localization and quantification. (C) SH‐SY5Y and (D) primary neuron show pTDP‐43. Quantitative analysis of cytoplasmic TDP‐43/pTDP‐43 volume (µm 3 ) was performed using a two‐way analysis of variance (ANOVA). Data are presented as mean ± standard error of the mean (SEM). Statistical significance was defined as p ≤ 0.05 (*), ≤ 0.01 (**), ≤ 0.001 (***), and ≤ 0.0001 (****). Scale bars = 15 µm.

Journal: Alzheimer's & Dementia

Article Title: Characterizing TDP‐43 involvement in vascular dementia

doi: 10.1002/alz.71196

Figure Lengend Snippet: Cytoplasmic mislocalization of Tar DNA‐binding protein 43 (TDP‐43) and the phosphorylated form (pTDP‐43) following 40% oxygen–glucose deprivation (OGD). Immunocytochemistry was performed on SH‐SY5Y cells and primary cortical neurons ( n = 3–4 biological replicates) to assess cytoplasmic redistribution of TDP‐43 and pTDP‐43 in response to 40% OGD. Cells were stained with anti–TDP‐43 or anti–pTDP‐43 (green), anti–βIII‐Tubulin or MAP2 (red), and 4′,6‐diamidino‐2‐phenylindole (DAPI) (blue). Only cytoplasmic colocalization of TDP‐43 or pTDP‐43 with neuronal markers is shown in yellow in merged images. Representative confocal micrographs were acquired at 60× magnification. (A) SH‐SY5Y and (B) primary neuron show cytoplasmic TDP‐43 localization and quantification. (C) SH‐SY5Y and (D) primary neuron show pTDP‐43. Quantitative analysis of cytoplasmic TDP‐43/pTDP‐43 volume (µm 3 ) was performed using a two‐way analysis of variance (ANOVA). Data are presented as mean ± standard error of the mean (SEM). Statistical significance was defined as p ≤ 0.05 (*), ≤ 0.01 (**), ≤ 0.001 (***), and ≤ 0.0001 (****). Scale bars = 15 µm.

Article Snippet: Sections were blocked (3% horse serum, 0.3% Triton X‐100 in PBS), then incubated overnight at 4°C with anti‐TDP‐43 or anti‐pTDP‐43 antibodies (Affinity Biosciences).

Techniques: Binding Assay, Immunocytochemistry, Staining