pt1 Search Results


94
ATCC e coli atcc 11303 seed suspension
E Coli Atcc 11303 Seed Suspension, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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dsijt  (ATCC)
94
ATCC dsijt
Dsijt, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/dsijt/product/ATCC
Average 94 stars, based on 1 article reviews
dsijt - by Bioz Stars, 2026-04
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96
InvivoGen mycostrip
Mycostrip, supplied by InvivoGen, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
mycostrip - by Bioz Stars, 2026-04
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94
Lee Biosolutions human nasal fluid
Human Nasal Fluid, supplied by Lee Biosolutions, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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91
Lee Biosolutions saliva samples
Saliva Samples, supplied by Lee Biosolutions, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 91 stars, based on 1 article reviews
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91
Santa Cruz Biotechnology pt1
Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, <t>PT1,</t> C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).
Pt1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pt1/product/Santa Cruz Biotechnology
Average 91 stars, based on 1 article reviews
pt1 - by Bioz Stars, 2026-04
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91
Lee Biosolutions human donor
Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, <t>PT1,</t> C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).
Human Donor, supplied by Lee Biosolutions, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 91 stars, based on 1 article reviews
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90
Greatcell Solar pt transparent catalyst pt1
Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, <t>PT1,</t> C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).
Pt Transparent Catalyst Pt1, supplied by Greatcell Solar, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
pt transparent catalyst pt1 - by Bioz Stars, 2026-04
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90
Thorlabs 1” translation stages thorlabs pt1
Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, <t>PT1,</t> C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).
1” Translation Stages Thorlabs Pt1, supplied by Thorlabs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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90
NORELL ubb pt-1
Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, <t>PT1,</t> C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).
Ubb Pt 1, supplied by NORELL, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
ubb pt-1 - by Bioz Stars, 2026-04
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90
Dyesol Inc platinum paste pt1
Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, <t>PT1,</t> C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).
Platinum Paste Pt1, supplied by Dyesol Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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90
Lawrence Livermore National Security LLC lawrence livermore national report ucrl-ma-110662 pt iv
Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, <t>PT1,</t> C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).
Lawrence Livermore National Report Ucrl Ma 110662 Pt Iv, supplied by Lawrence Livermore National Security LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/lawrence livermore national report ucrl-ma-110662 pt iv/product/Lawrence Livermore National Security LLC
Average 90 stars, based on 1 article reviews
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Image Search Results


Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, PT1, C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).

Journal: PLoS ONE

Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders

doi: 10.1371/journal.pone.0240517

Figure Lengend Snippet: Mitochondrial-deficient patient fibroblasts were treated with AMPK agonists A-769662, PT1, C24, ZLN024, AICAR, DMSO (vehicle), or PBS (untreated control). Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG. Viability was assessed by calcein AM fluorescence intensity. Experiments were performed in triplicate on at least three separate occasions and also included fibroblasts from a healthy control (“Normal”). Bars represent standard error of the mean. Asterisks represent statistical significance (*p<0.05).

Article Snippet: Cells were treated with either DMSO or AMPK agonists, PT1 (Santa Cruz Biotechnology, Santa Cruz, CA; sc-361299), A-769662 (Apex Bio, Houston, TX; A3963), ZLN024 (Sigma-Aldrich, St. Louis, MO; SML0900), and C24 (Medchem Express, Princeton, NJ; HY-15840).

Techniques: Control, Fluorescence

Mitochondrial-deficient patient fibroblasts were treated with the AMPK agonist PT1 or DMSO (vehicle) and morphology was visualized by phase contrast microscopy. Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG.

Journal: PLoS ONE

Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders

doi: 10.1371/journal.pone.0240517

Figure Lengend Snippet: Mitochondrial-deficient patient fibroblasts were treated with the AMPK agonist PT1 or DMSO (vehicle) and morphology was visualized by phase contrast microscopy. Cell lines are from patients with a defect in ( A ) SURF1, ( B ) COX10, ( C ) CI, and ( D ) POLG.

Article Snippet: Cells were treated with either DMSO or AMPK agonists, PT1 (Santa Cruz Biotechnology, Santa Cruz, CA; sc-361299), A-769662 (Apex Bio, Houston, TX; A3963), ZLN024 (Sigma-Aldrich, St. Louis, MO; SML0900), and C24 (Medchem Express, Princeton, NJ; HY-15840).

Techniques: Microscopy

SURF1-deficient patient fibroblasts were treated with PT1 or DMSO (vehicle) for 24 hours and expression of PGC-1 and catalase/SOD2 RNA was evaluated by qPCR (n = 3). Results are normalized to actin. Asterisks represent statistical significance (*p<0.05).

Journal: PLoS ONE

Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders

doi: 10.1371/journal.pone.0240517

Figure Lengend Snippet: SURF1-deficient patient fibroblasts were treated with PT1 or DMSO (vehicle) for 24 hours and expression of PGC-1 and catalase/SOD2 RNA was evaluated by qPCR (n = 3). Results are normalized to actin. Asterisks represent statistical significance (*p<0.05).

Article Snippet: Cells were treated with either DMSO or AMPK agonists, PT1 (Santa Cruz Biotechnology, Santa Cruz, CA; sc-361299), A-769662 (Apex Bio, Houston, TX; A3963), ZLN024 (Sigma-Aldrich, St. Louis, MO; SML0900), and C24 (Medchem Express, Princeton, NJ; HY-15840).

Techniques: Expressing

COX10-deficient patient fibroblasts were transfected with AMPK-specific siRNA (siAMPK) or control siRNA (siCNT). Following transfection, cells were ( A ) evaluated for protein expression by western blotting, or ( B ) treated with PT1 or DMSO (vehicle) for an additional 6 days and then evaluated for viability by calcein-AM fluorescence assay and ( C ) morphology by phase contrast microscopy.

Journal: PLoS ONE

Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders

doi: 10.1371/journal.pone.0240517

Figure Lengend Snippet: COX10-deficient patient fibroblasts were transfected with AMPK-specific siRNA (siAMPK) or control siRNA (siCNT). Following transfection, cells were ( A ) evaluated for protein expression by western blotting, or ( B ) treated with PT1 or DMSO (vehicle) for an additional 6 days and then evaluated for viability by calcein-AM fluorescence assay and ( C ) morphology by phase contrast microscopy.

Article Snippet: Cells were treated with either DMSO or AMPK agonists, PT1 (Santa Cruz Biotechnology, Santa Cruz, CA; sc-361299), A-769662 (Apex Bio, Houston, TX; A3963), ZLN024 (Sigma-Aldrich, St. Louis, MO; SML0900), and C24 (Medchem Express, Princeton, NJ; HY-15840).

Techniques: Transfection, Control, Expressing, Western Blot, Fluorescence, Microscopy

SURF1 and POLG-deficient patient cells were treated with PT1 or DMSO (vehicle) for 48 hrs and ( A ) basal, ( B ) ATP-coupled, and ( C ) maximal OCR were measured by the XF96 analyzer. All experiments were done in triplicate. Maximal OCR was measured after FCCP injection and ATP-coupled OCR following oligomycin injection. Results are normalized to total protein concentration. Data are represented as the mean ± standard error of the mean. *p<0.05.

Journal: PLoS ONE

Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders

doi: 10.1371/journal.pone.0240517

Figure Lengend Snippet: SURF1 and POLG-deficient patient cells were treated with PT1 or DMSO (vehicle) for 48 hrs and ( A ) basal, ( B ) ATP-coupled, and ( C ) maximal OCR were measured by the XF96 analyzer. All experiments were done in triplicate. Maximal OCR was measured after FCCP injection and ATP-coupled OCR following oligomycin injection. Results are normalized to total protein concentration. Data are represented as the mean ± standard error of the mean. *p<0.05.

Article Snippet: Cells were treated with either DMSO or AMPK agonists, PT1 (Santa Cruz Biotechnology, Santa Cruz, CA; sc-361299), A-769662 (Apex Bio, Houston, TX; A3963), ZLN024 (Sigma-Aldrich, St. Louis, MO; SML0900), and C24 (Medchem Express, Princeton, NJ; HY-15840).

Techniques: Injection, Protein Concentration

SURF1 and POLG-deficient patient cells were supplemented with PT1 or DMSO (vehicle) for 48 hrs. ( A ) ATP levels were measured by CellTiter-Glo ATP Assay, and results were normalized to total protein concentration. ( B ) ROS were levels measured by the CellROX Deep Red Flow Cytometry Assay. All experiments were done in triplicate. Data are represented as the mean ± standard error of the mean. *p<0.05.

Journal: PLoS ONE

Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders

doi: 10.1371/journal.pone.0240517

Figure Lengend Snippet: SURF1 and POLG-deficient patient cells were supplemented with PT1 or DMSO (vehicle) for 48 hrs. ( A ) ATP levels were measured by CellTiter-Glo ATP Assay, and results were normalized to total protein concentration. ( B ) ROS were levels measured by the CellROX Deep Red Flow Cytometry Assay. All experiments were done in triplicate. Data are represented as the mean ± standard error of the mean. *p<0.05.

Article Snippet: Cells were treated with either DMSO or AMPK agonists, PT1 (Santa Cruz Biotechnology, Santa Cruz, CA; sc-361299), A-769662 (Apex Bio, Houston, TX; A3963), ZLN024 (Sigma-Aldrich, St. Louis, MO; SML0900), and C24 (Medchem Express, Princeton, NJ; HY-15840).

Techniques: ATP Assay, Protein Concentration, Flow Cytometry

Sodium iodate-treated (+SI) or untreated (-SI) mice were treated with PT1 or DMSO (vehicle). The four groups (n = 5 mice per group) were evaluated by ( A ) fundoscopy; ( B ) H&E staining of retinal sections showing the outer nuclear layer (ONL; white bars), pigmented cells (black arrows), and photoreceptor inner outer segment (IS/OS) morphology; ( C ) quantitative assessment of ONL thickness; and ( D ) functional evaluation by ERG with measurements of the dark-adapted photoreceptor response (scotopic a-wave) and inner retinal response (scotopic b-wave). ERG data represent 3–5 mice per group and are plotted as mean ± SEM. *P<0.05; **P<0.01; ***P<0.001; ****P<0.0001.

Journal: PLoS ONE

Article Title: AMP-independent activator of AMPK for treatment of mitochondrial disorders

doi: 10.1371/journal.pone.0240517

Figure Lengend Snippet: Sodium iodate-treated (+SI) or untreated (-SI) mice were treated with PT1 or DMSO (vehicle). The four groups (n = 5 mice per group) were evaluated by ( A ) fundoscopy; ( B ) H&E staining of retinal sections showing the outer nuclear layer (ONL; white bars), pigmented cells (black arrows), and photoreceptor inner outer segment (IS/OS) morphology; ( C ) quantitative assessment of ONL thickness; and ( D ) functional evaluation by ERG with measurements of the dark-adapted photoreceptor response (scotopic a-wave) and inner retinal response (scotopic b-wave). ERG data represent 3–5 mice per group and are plotted as mean ± SEM. *P<0.05; **P<0.01; ***P<0.001; ****P<0.0001.

Article Snippet: Cells were treated with either DMSO or AMPK agonists, PT1 (Santa Cruz Biotechnology, Santa Cruz, CA; sc-361299), A-769662 (Apex Bio, Houston, TX; A3963), ZLN024 (Sigma-Aldrich, St. Louis, MO; SML0900), and C24 (Medchem Express, Princeton, NJ; HY-15840).

Techniques: Staining, Functional Assay