Journal:

Article Title: Processing MALDI Mass Spectra to Improve Mass Spectral Direct Tissue Analysis

doi: 10.1016/j.ijms.2006.10.005

Figure Lengend Snippet: MALDI MS profile spectra acquired from three sections from different tissues. (a) Raw spectra; (b) spectra that have been baseline corrected using ProTSData software.

Article Snippet: Robust local regression estimation [ 36 ] shows very good ability to adapt to variable background signals, but the technique is severely disadvantaged with lengthy computational time to process a profile spectrum of average size, 40-50 s. Incorporation of the local estimation algorithm in ProTSData (Biodesix, Steamboat Springs, CO) into a batch process has yielded the most widely applicable approach.

Techniques: Software