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Image Search Results
Journal: Journal of Pharmaceutical and Biomedical Analysis
Article Title: Forced degradation studies of medroxyprogesterone acetate injectable suspensions (150 mg/ml) with implementation of HPLC, mass spectrometry, and QSAR techniques
doi: 10.1016/j.jpba.2020.113352
Figure Lengend Snippet: Chemical structures for medroxyprogesterone acetate (MPA) and its known impurities . A - 6-hydroxymedroxyprogesterone acetate (6β-hydroxy-6-methyl-3,20-dioxopregn-4-en-17-yl acetate); B – medroxyprogesterone (17-hydroxy-6α-methylpregn-4-ene-3,20-dione); C - 6α,17α-dimethyl-3,17-dioxo- d -homoandrost-4-en-17α-yl acetate; D - 6-epimedroxyprogesterone acetate (6β-methyl-3,20-dioxopregn-4-en-17-yl acetate); E - 6-methylenehydroxyprogesterone acetate (6-methylidene-3,20-dioxopregn-4-en-17-yl acetate); F - 4,5-dihydromedroxyprogesterone acetate (6α-methyl-3,20-dioxo-5β-pregn-17-yl acetate); G - megestrol acetate (6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate); H - hydroxyprogesterone acetate (3,20-dioxopregn-4-en-17-yl acetate); I - 17β-hydroxy-6α,17α-dimethyl- d -homoandrost-4-en-3,17-dione.
Article Snippet:
Techniques:
Journal: Journal of Pharmaceutical and Biomedical Analysis
Article Title: Forced degradation studies of medroxyprogesterone acetate injectable suspensions (150 mg/ml) with implementation of HPLC, mass spectrometry, and QSAR techniques
doi: 10.1016/j.jpba.2020.113352
Figure Lengend Snippet: Example chromatogram for Reference Solution A with assignments for respective medroxyprogesterone impurities [ , , ], including relative retention times and +/- 2% RRT range observed for implemented chromatographic conditions.
Article Snippet:
Techniques: