prisma cell Search Results


single-cell dna sequencing  (Prisma Biotech Corporation)
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Prisma Biotech Corporation single-cell dna sequencing
Mutations detected by bulk <t> DNA </t> next-generation <t> sequencing </t> in a patient with advSM
Single Cell Dna Sequencing, supplied by Prisma Biotech Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/single-cell dna sequencing/product/Prisma Biotech Corporation
Average 90 stars, based on 1 article reviews
single-cell dna sequencing - by Bioz Stars, 2026-03
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prisma cell line  (Broad Institute Inc)
90
Broad Institute Inc prisma cell line
Mutations detected by bulk <t> DNA </t> next-generation <t> sequencing </t> in a patient with advSM
Prisma Cell Line, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prisma cell line/product/Broad Institute Inc
Average 90 stars, based on 1 article reviews
prisma cell line - by Bioz Stars, 2026-03
90/100 stars
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prisma cell  (GraphPad Software Inc)
90
GraphPad Software Inc prisma cell
Mutations detected by bulk <t> DNA </t> next-generation <t> sequencing </t> in a patient with advSM
Prisma Cell, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prisma cell/product/GraphPad Software Inc
Average 90 stars, based on 1 article reviews
prisma cell - by Bioz Stars, 2026-03
90/100 stars
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prisma cell library  (Broad Institute Inc)
90
Broad Institute Inc prisma cell library
Mutations detected by bulk <t> DNA </t> next-generation <t> sequencing </t> in a patient with advSM
Prisma Cell Library, supplied by Broad Institute Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prisma cell library/product/Broad Institute Inc
Average 90 stars, based on 1 article reviews
prisma cell library - by Bioz Stars, 2026-03
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Mutations detected by bulk DNA next-generation sequencing in a patient with advSM

Journal: Blood Advances

Article Title: Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by single-cell DNA sequencing

doi: 10.1182/bloodadvances.2020003980

Figure Lengend Snippet: Mutations detected by bulk DNA next-generation sequencing in a patient with advSM

Article Snippet: The authors thank Renshiang Jhou (Prisma Biotech Corporation, Taipei, Taiwan) for help with the single-cell DNA sequencing and bioinformatics analysis.

Techniques: Next-Generation Sequencing

Clonal evolution by serial bulk DNA next-generation sequencing and single-cell DNA-seq in a patient with advSM. (A) Clonal evolution in response to midostaurin and azacitidine by serial bulk DNA-seq. Founding ASXL1, SRSF2, and RUNX1 mutations persisted during midostaurin and azacitidine treatment. KIT and EZH2 mutation burden were initially high at the PB1 time point and were significantly diminished after midostaurin treatment. At the BM time point, allele frequency of NRAS and TET2 mutations were initially high, but they later decreased as a result of azacitidine treatment. KIT and EZH2 mutations, followed by disease relapse, recurred with an additional new mutation site at RUNX1 R162S. The results were projected into a trend line with VAF shown on the Y-axis and collected samples listed below the graph. (B) Clonal evolution in response to treatment with midostaurin and azacitidine determined by single-cell DNA-seq. After treatment with midostaurin for 3 months, significant reduction of KIT D816V and EZH2 mutations with significant expansion of TET2 and NRAS mutations was detected. The addition of azacitidine resulted in significant reduction of TET2 and NRAS mutations and progressive expansion of KIT D816V and EZH2 mutations. Acquisition of a new mutation (RUNX1 R162S) was followed by disease progression and rapid death after 8 months of combinatorial treatment. The results of single-cell DNA-seq are shown in a bar graph and fish plot with sequenced cell numbers listed below as combined blood and bone marrow cell count results. dRUNX1, double RUNX1 mutations.

Journal: Blood Advances

Article Title: Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by single-cell DNA sequencing

doi: 10.1182/bloodadvances.2020003980

Figure Lengend Snippet: Clonal evolution by serial bulk DNA next-generation sequencing and single-cell DNA-seq in a patient with advSM. (A) Clonal evolution in response to midostaurin and azacitidine by serial bulk DNA-seq. Founding ASXL1, SRSF2, and RUNX1 mutations persisted during midostaurin and azacitidine treatment. KIT and EZH2 mutation burden were initially high at the PB1 time point and were significantly diminished after midostaurin treatment. At the BM time point, allele frequency of NRAS and TET2 mutations were initially high, but they later decreased as a result of azacitidine treatment. KIT and EZH2 mutations, followed by disease relapse, recurred with an additional new mutation site at RUNX1 R162S. The results were projected into a trend line with VAF shown on the Y-axis and collected samples listed below the graph. (B) Clonal evolution in response to treatment with midostaurin and azacitidine determined by single-cell DNA-seq. After treatment with midostaurin for 3 months, significant reduction of KIT D816V and EZH2 mutations with significant expansion of TET2 and NRAS mutations was detected. The addition of azacitidine resulted in significant reduction of TET2 and NRAS mutations and progressive expansion of KIT D816V and EZH2 mutations. Acquisition of a new mutation (RUNX1 R162S) was followed by disease progression and rapid death after 8 months of combinatorial treatment. The results of single-cell DNA-seq are shown in a bar graph and fish plot with sequenced cell numbers listed below as combined blood and bone marrow cell count results. dRUNX1, double RUNX1 mutations.

Article Snippet: The authors thank Renshiang Jhou (Prisma Biotech Corporation, Taipei, Taiwan) for help with the single-cell DNA sequencing and bioinformatics analysis.

Techniques: Next-Generation Sequencing, DNA Sequencing, Mutagenesis, Biomarker Discovery, Cell Counting

Mutations detected by single-cell DNA sequencing in a patient with advSM

Journal: Blood Advances

Article Title: Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by single-cell DNA sequencing

doi: 10.1182/bloodadvances.2020003980

Figure Lengend Snippet: Mutations detected by single-cell DNA sequencing in a patient with advSM

Article Snippet: The authors thank Renshiang Jhou (Prisma Biotech Corporation, Taipei, Taiwan) for help with the single-cell DNA sequencing and bioinformatics analysis.

Techniques: DNA Sequencing