prcomp Search Results


stats package, prcomp function  (RStudio)
90
RStudio stats package, prcomp function
Stats Package, Prcomp Function, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
stats package, prcomp function - by Bioz Stars, 2026-03
90/100 stars
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prcomp  (RStudio)
90
RStudio prcomp
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp/product/RStudio
Average 90 stars, based on 1 article reviews
prcomp - by Bioz Stars, 2026-03
90/100 stars
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prcomp module  (RStudio)
90
RStudio prcomp module
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp Module, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp module/product/RStudio
Average 90 stars, based on 1 article reviews
prcomp module - by Bioz Stars, 2026-03
90/100 stars
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prcomp and infomax functions  (InfoMax Inc)
90
InfoMax Inc prcomp and infomax functions
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp And Infomax Functions, supplied by InfoMax Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp and infomax functions/product/InfoMax Inc
Average 90 stars, based on 1 article reviews
prcomp and infomax functions - by Bioz Stars, 2026-03
90/100 stars
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prcomp function  (SAS institute)
90
SAS institute prcomp function
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp Function, supplied by SAS institute, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp function/product/SAS institute
Average 90 stars, based on 1 article reviews
prcomp function - by Bioz Stars, 2026-03
90/100 stars
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prcomp  (Illumina Inc)
90
Illumina Inc prcomp
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp, supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp/product/Illumina Inc
Average 90 stars, based on 1 article reviews
prcomp - by Bioz Stars, 2026-03
90/100 stars
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prcomp function v4.2.1  (RStudio)
90
RStudio prcomp function v4.2.1
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp Function V4.2.1, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp function v4.2.1/product/RStudio
Average 90 stars, based on 1 article reviews
prcomp function v4.2.1 - by Bioz Stars, 2026-03
90/100 stars
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prcomp function in rstudio 2 v1.1.383  (RStudio)
90
RStudio prcomp function in rstudio 2 v1.1.383
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp Function In Rstudio 2 V1.1.383, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp function in rstudio 2 v1.1.383/product/RStudio
Average 90 stars, based on 1 article reviews
prcomp function in rstudio 2 v1.1.383 - by Bioz Stars, 2026-03
90/100 stars
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prcomp v.3.6.2  (RStudio)
90
RStudio prcomp v.3.6.2
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp V.3.6.2, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp v.3.6.2/product/RStudio
Average 90 stars, based on 1 article reviews
prcomp v.3.6.2 - by Bioz Stars, 2026-03
90/100 stars
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prcomp method  (RStudio)
90
RStudio prcomp method
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp Method, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp method/product/RStudio
Average 90 stars, based on 1 article reviews
prcomp method - by Bioz Stars, 2026-03
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prcomp function in rstudio v4.3.1  (RStudio)
90
RStudio prcomp function in rstudio v4.3.1
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp Function In Rstudio V4.3.1, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp function in rstudio v4.3.1/product/RStudio
Average 90 stars, based on 1 article reviews
prcomp function in rstudio v4.3.1 - by Bioz Stars, 2026-03
90/100 stars
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prcomp and biplot commands  (RStudio)
90
RStudio prcomp and biplot commands
Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component <t>analysis</t> <t>(PCA)</t> of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using <t>prcomp</t> (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).
Prcomp And Biplot Commands, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/prcomp and biplot commands/product/RStudio
Average 90 stars, based on 1 article reviews
prcomp and biplot commands - by Bioz Stars, 2026-03
90/100 stars
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Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component analysis (PCA) of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using prcomp (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).

Journal: The Journal of Biological Chemistry

Article Title: The RNA-binding protein Nab2 regulates the proteome of the developing Drosophila brain

doi: 10.1016/j.jbc.2021.100877

Figure Lengend Snippet: Quantitative proteomic analysis of developmentally timed pupal brains reveals a role for Nab2 in neurodevelopment. A , principal component analysis (PCA) of proteomic data from 24 h after puparium formation Drosophila brains from ten biological replicates of control , Nab2 ex3 , and Nab2 oe flies (control = C155>Gal4, w 1118 ; Nab2 ex3 = C155>Gal4;;Nab2 ex3 ; Nab2 oe = C155>Gal4;Nab2 EP3716 ;Nab2 ex3 ) show results cluster based on the genotype and that Nab2 ex3 and Nab2 oe are distinct from control and each other. PCA was performed in RStudio using prcomp (default stats package v3.5.1), and summed peptide intensities were used as the input. B and C , volcano plots show proteins differentially expressed in each Nab2 genotype compared with the control [ B , Nab2 ex3 (346; 188 down and 158 up) and C , Nab2 oe compared with the control (514; 285 down and 229 up)]. Ten biological replicates (n = 10) per genotype (20 brains per pooled biological replicate) with 30 technical replicates in total. Significance thresholds: log 2 (≥0.32 and ≤−0.32) and −log 10 ( p -value) ≥1.3; thresholds were based on power calculation and instrumental limits. Protein abundance change (down or up) indicated on each side of the plot (log 2 Nab2 ex3 /Cont or Nab2 oe /Cont: gray = not significant, blue ≤ −0.32, red ≥ 0.32). The number of differentially expressed proteins to total detected proteins is shown atop the graph; 346 of 4302 Nab2 ex3 proteins are differentially expressed ( B ) and 514 of 4302 Nab2 oe proteins are differentially expressed ( C ). D – G , the enriched gene ontology terms from FlyEnrichr database for biological process are shown for proteins increased log 2 ( Nab2 ex3 /Cont) ≥0.32 in panel D Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel E Nab2 oe and decreased log 2 ( Nab2 ex3 /Cont) ≤−0.32 in panel F Nab2 ex3 and log 2 ( Nab2 oe /Cont) in panel G Nab2 oe . The bars shown correspond to the top ten c-scores (c-score = ln(adj p -val) ∗ z-score) in each dataset (adjusted p -value <0.05) ( , , ).

Article Snippet: PCA was performed in RStudio using prcomp (default stats package v3.5.1) and summed peptide intensities were used as input ( , , , ).

Techniques: Control, Quantitative Proteomics