Journal: Vaccine: X

Article Title: Emerging vaccine manufacturers are innovating for the next decade

doi: 10.1016/j.jvacx.2020.100066

Figure Lengend Snippet: Vaccines produced by DCVMN corporate members as of 2019. Matrix of 196 vaccines produced by 38 DCVMN members (as of October 2019). Of the reported vaccines, 31 manufacturers responded to the DCVMN Progress Report Survey (launched in June 2019), while an additional 7 manufacturer’s vaccine availability report derives from data in the public domain. Vaccine pre-qualified by WHO are indicated in black. Five DCVMN members are currently not producing vaccines. Manufacturers name are as follows: AMSON Vaccines & Pharmaceuticals Ltd., Pakistan; Beijing Minhai Biotechnology Co., Ltd., China; Bharat Biotech International Ltd., India; PT BioFarma, Indonesia; Biological E. Ltd., India; Bio-Manguinhos/Fiocruz, Brazil; BioNet-Asia Co., Ltd., Thailand; Birmex, Laboratorios de Biológico y Reactivos de México, Mexico; CDBIO, Liaoning Chengda Biotechnology, China; Chanhchun BCHT Biotechnology Co., China; CNBG, CNBC consists of 6 Institutes, including National Vaccine and Serum Institute (NVSI), Changchun Institute, Chengdu Institute, Lanzhou Institute, Shanghai, Wuhan, and 2 international trading companies in Beijing; CPL Biologicals Pvt. Ltd., India; Eubiologics Co., Ltd., Republic of Korea; GPO, The Government Pharmeceutical Organization, Thailand; Green Cross, Republic of Korea; Green Signal Bio Pharma Ltd., India; Haffkine Bio-Pharmaceutical Corporation Ltd., India; IMBCAMS, The Institute of Medical Biology, Chinese Academy of Medical Sciences, China; Incepta Pharmaceuticals Ltd., Bangladesh; Indian Immunologicals Ltd., India; Instituto Butantan, Brazil; IVAC, Institute of vaccines and medical biologicals, Vietnam; Korea Vaccine, Republic of Korea; LG Chem, Republic of Korea; Nanolek LLC., Russia; Panacea Biotech Ltd., India; POLYVAC, Center for research and production of vaccines and biologicals, Vietnam; Queen Saovabha Memorial Institute, Thai Red Cross Society, Thailand; Serum Institute of India, India; Sinergium Biotech, Argentina; Sinovac Biotech Ltd., China; SK bioscience, SK Group, Republic of Korea; SPbSRIVS, St. Petersburg Research Institute of Vaccines and Serums and Bacterial preparations plant, Russia; Vabiotech, Company for Vaccine and Biological production No. 1, Vietnam; Walvax Biotechnology Co., Ltd., China; Xiamen Innovax Biotech Co., Ltd., China; ZhiFei Biological Products Co., Ltd., China; Zydus Cadila, India. Biovac Institute, South Africa; BravoVax Co., Ltd., China, Medigen Vaccine Biologics Co., Taiwan; Pasteur Institute of India, India; and VINS Bioproducts Ltd., India are not currently (as of survey responses of October 2019) producing vaccines. The difference between number of PQed vaccines shown in and is due to the fact that the latter only considers vaccines currently being produced (as to our survey question) while indicates when these vaccines were pre-qualified but does not mean they are currently being produced. *Note postscript : PCV 10 vaccine by Serum Institute received WHO PQ on 17th December 2019. cf. https://extranet.who.int/gavi/PQ_Web/PreviewVaccine.aspx?nav=0&ID=384 ; bivalent HPV vaccine from Xiamen Innovax approved by Chinese NMPA on 2nd January 2020. cf. https://www.sixthtone.com/news/1005031/china-approves-production-of-first-domestic-hpv-vaccine ; PCV 13 vaccine from Walvax approved by Chinese NMPA on 3rd January 2020. http://subsites.chinadaily.com.cn/nmpa/2020-01/03/c_445837.htm ; Varicella vaccine from SK bioscience received WHO PQ in 9th December 2019. https://extranet.who.int/gavi/PQ_Web/Default.aspx?nav=2 . (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Article Snippet: ; Panacea Biotech Ltd.; POLYVAC; Queen Saovabha Memorial Institute; Serum Institute of India; Sinergium Biotech; Sinovac Biotech Ltd.; SK bioscience; SPbSRIVS; Vabiotech; Walvax Biotechnology Co. Ltd.; Xiamen Innovax Biotech Co. Ltd.; Zydus Cadila; Biovac Institute; BravoVax Co. Ltd.; Medigen Vaccine Biologics Co.; Pasteur Institute of India; and VINS Bioproducts Ltd. We would also like to thank the DCVMN Executive Committee for their ongoing support and guidance.

Techniques: Vaccines, Produced