plvap Search Results


hs00985639 plvap taqman assay thermofisher scientific  (Thermo Fisher)
92
Thermo Fisher hs00985639 plvap taqman assay thermofisher scientific
Hs00985639 Plvap Taqman Assay Thermofisher Scientific, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/pm37810232-193-20-24?v=Thermo+Fisher
Average 92 stars, based on 1 article reviews
hs00985639 plvap taqman assay thermofisher scientific - by Bioz Stars, 2026-07
92/100 stars
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anti plvap antibody  (Bioss)
94
Bioss anti plvap antibody
A. Flowchart of the experiment on vascular endothelial cell-specific <t>Plvap</t> knockdown to prevent bleomycin-induced pulmonary fibrosis. Vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using the adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC, and modeled by intratracheal dropleting of bleomycin for 3 weeks 21 days after AAV injection. B. Immunofluorescence (IF) shows increased fluorescence intensity of Plvap in endothelial cells of mouse lung tissues in the Plvap +/+ group and low expression of Plvap in endothelial cells of mouse lung tissues in the Plvap EC KD group. Blue is DAPI, white <t>is</t> <t>Cd31,</t> and red is Plvap. C-D. Histopathological of the lungs of mice 4 weeks after bleomycin modeling, Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution in the lungs, and no obvious areas of fibrous occlusion were seen in the lung tissues, and the histograms showed statistically significant differences. E. Bar graphs showing lung function indexes (TVb, EF50) of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling,the results showed that the lung function of Plvap EC KO mice was significantly elevated. (*p<0.05) F. Bar graph showing the gene expression of α-SMA, Collagen I (collagen type I α 1 chain), Eln (elastin), Fn1 (fibronectin 1), Acta2, Ctgf (connective tissue growth factor) in lung tissues of preventive group of Plvap EC KO mice and control group of Plvap +/+ mice after 4 weeks of bleomycin modeling. G. Bar graph showing the gene expression of pro-fibrotic cytokines Tgfb1, Il6, and Cxcl2 in lung tissues of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling. H. Flow chart of the experimental procedure for vascular endothelial cell-specific Plvap knockdown for bleomycin-induced pulmonary fibrosis. After 1 week of intratracheal drip bleomycin modeling, vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC for 21 days. The observation indexes included: lung function, HE staining, Masson staining and Sirius staining of lung tissues. I-J: Histopathological of the lungs of mice 4 weeks after bleomycin modeling, HE staining could observe signs of pulmonary fibrosis such as structural destruction of lung tissue, thickening of alveolar septa, and extensive fibrous foci, etc., and the lesions in the lungs of Plvap EC KO mice were significantly milder than those in the control group, and the histograms showed statistically significant differences in the differences. Sirius Red and Masson staining showed that the lungs of Plvap EC KO mice had Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution, and no obvious areas of fibrous occlusion were seen in the lung tissue, and the histograms showed statistically significant differences. K. Bar graphs showing lung function indices (TVb, EF50) after 4 weeks of bleomycin modeling in Plvap EC KO mice in the treatment group and in Plvap +/+ mice in the control group, and the results showed that the lung function was significantly elevated in Plvap EC KO mice. (***p<0.001, ****p<0.0001)
Anti Plvap Antibody, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/bio_rxiv__2024__03__12__584592-64-12-14?v=Bioss
Average 94 stars, based on 1 article reviews
anti plvap antibody - by Bioz Stars, 2026-07
94/100 stars
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nbp1  (Novus Biologicals)
93
Novus Biologicals nbp1
A. Flowchart of the experiment on vascular endothelial cell-specific <t>Plvap</t> knockdown to prevent bleomycin-induced pulmonary fibrosis. Vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using the adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC, and modeled by intratracheal dropleting of bleomycin for 3 weeks 21 days after AAV injection. B. Immunofluorescence (IF) shows increased fluorescence intensity of Plvap in endothelial cells of mouse lung tissues in the Plvap +/+ group and low expression of Plvap in endothelial cells of mouse lung tissues in the Plvap EC KD group. Blue is DAPI, white <t>is</t> <t>Cd31,</t> and red is Plvap. C-D. Histopathological of the lungs of mice 4 weeks after bleomycin modeling, Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution in the lungs, and no obvious areas of fibrous occlusion were seen in the lung tissues, and the histograms showed statistically significant differences. E. Bar graphs showing lung function indexes (TVb, EF50) of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling,the results showed that the lung function of Plvap EC KO mice was significantly elevated. (*p<0.05) F. Bar graph showing the gene expression of α-SMA, Collagen I (collagen type I α 1 chain), Eln (elastin), Fn1 (fibronectin 1), Acta2, Ctgf (connective tissue growth factor) in lung tissues of preventive group of Plvap EC KO mice and control group of Plvap +/+ mice after 4 weeks of bleomycin modeling. G. Bar graph showing the gene expression of pro-fibrotic cytokines Tgfb1, Il6, and Cxcl2 in lung tissues of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling. H. Flow chart of the experimental procedure for vascular endothelial cell-specific Plvap knockdown for bleomycin-induced pulmonary fibrosis. After 1 week of intratracheal drip bleomycin modeling, vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC for 21 days. The observation indexes included: lung function, HE staining, Masson staining and Sirius staining of lung tissues. I-J: Histopathological of the lungs of mice 4 weeks after bleomycin modeling, HE staining could observe signs of pulmonary fibrosis such as structural destruction of lung tissue, thickening of alveolar septa, and extensive fibrous foci, etc., and the lesions in the lungs of Plvap EC KO mice were significantly milder than those in the control group, and the histograms showed statistically significant differences in the differences. Sirius Red and Masson staining showed that the lungs of Plvap EC KO mice had Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution, and no obvious areas of fibrous occlusion were seen in the lung tissue, and the histograms showed statistically significant differences. K. Bar graphs showing lung function indices (TVb, EF50) after 4 weeks of bleomycin modeling in Plvap EC KO mice in the treatment group and in Plvap +/+ mice in the control group, and the results showed that the lung function was significantly elevated in Plvap EC KO mice. (***p<0.001, ****p<0.0001)
Nbp1, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/pmc10558774-2-6-2?v=Novus+Biologicals
Average 93 stars, based on 1 article reviews
nbp1 - by Bioz Stars, 2026-07
93/100 stars
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pv 9000 kits  (OriGene)
90
OriGene pv 9000 kits
A. Flowchart of the experiment on vascular endothelial cell-specific <t>Plvap</t> knockdown to prevent bleomycin-induced pulmonary fibrosis. Vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using the adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC, and modeled by intratracheal dropleting of bleomycin for 3 weeks 21 days after AAV injection. B. Immunofluorescence (IF) shows increased fluorescence intensity of Plvap in endothelial cells of mouse lung tissues in the Plvap +/+ group and low expression of Plvap in endothelial cells of mouse lung tissues in the Plvap EC KD group. Blue is DAPI, white <t>is</t> <t>Cd31,</t> and red is Plvap. C-D. Histopathological of the lungs of mice 4 weeks after bleomycin modeling, Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution in the lungs, and no obvious areas of fibrous occlusion were seen in the lung tissues, and the histograms showed statistically significant differences. E. Bar graphs showing lung function indexes (TVb, EF50) of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling,the results showed that the lung function of Plvap EC KO mice was significantly elevated. (*p<0.05) F. Bar graph showing the gene expression of α-SMA, Collagen I (collagen type I α 1 chain), Eln (elastin), Fn1 (fibronectin 1), Acta2, Ctgf (connective tissue growth factor) in lung tissues of preventive group of Plvap EC KO mice and control group of Plvap +/+ mice after 4 weeks of bleomycin modeling. G. Bar graph showing the gene expression of pro-fibrotic cytokines Tgfb1, Il6, and Cxcl2 in lung tissues of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling. H. Flow chart of the experimental procedure for vascular endothelial cell-specific Plvap knockdown for bleomycin-induced pulmonary fibrosis. After 1 week of intratracheal drip bleomycin modeling, vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC for 21 days. The observation indexes included: lung function, HE staining, Masson staining and Sirius staining of lung tissues. I-J: Histopathological of the lungs of mice 4 weeks after bleomycin modeling, HE staining could observe signs of pulmonary fibrosis such as structural destruction of lung tissue, thickening of alveolar septa, and extensive fibrous foci, etc., and the lesions in the lungs of Plvap EC KO mice were significantly milder than those in the control group, and the histograms showed statistically significant differences in the differences. Sirius Red and Masson staining showed that the lungs of Plvap EC KO mice had Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution, and no obvious areas of fibrous occlusion were seen in the lung tissue, and the histograms showed statistically significant differences. K. Bar graphs showing lung function indices (TVb, EF50) after 4 weeks of bleomycin modeling in Plvap EC KO mice in the treatment group and in Plvap +/+ mice in the control group, and the results showed that the lung function was significantly elevated in Plvap EC KO mice. (***p<0.001, ****p<0.0001)
Pv 9000 Kits, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/pmc07210174-191-5-7?v=OriGene
Average 90 stars, based on 1 article reviews
pv 9000 kits - by Bioz Stars, 2026-07
90/100 stars
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step kit pv 6001  (OriGene)
92
OriGene step kit pv 6001
A. Flowchart of the experiment on vascular endothelial cell-specific <t>Plvap</t> knockdown to prevent bleomycin-induced pulmonary fibrosis. Vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using the adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC, and modeled by intratracheal dropleting of bleomycin for 3 weeks 21 days after AAV injection. B. Immunofluorescence (IF) shows increased fluorescence intensity of Plvap in endothelial cells of mouse lung tissues in the Plvap +/+ group and low expression of Plvap in endothelial cells of mouse lung tissues in the Plvap EC KD group. Blue is DAPI, white <t>is</t> <t>Cd31,</t> and red is Plvap. C-D. Histopathological of the lungs of mice 4 weeks after bleomycin modeling, Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution in the lungs, and no obvious areas of fibrous occlusion were seen in the lung tissues, and the histograms showed statistically significant differences. E. Bar graphs showing lung function indexes (TVb, EF50) of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling,the results showed that the lung function of Plvap EC KO mice was significantly elevated. (*p<0.05) F. Bar graph showing the gene expression of α-SMA, Collagen I (collagen type I α 1 chain), Eln (elastin), Fn1 (fibronectin 1), Acta2, Ctgf (connective tissue growth factor) in lung tissues of preventive group of Plvap EC KO mice and control group of Plvap +/+ mice after 4 weeks of bleomycin modeling. G. Bar graph showing the gene expression of pro-fibrotic cytokines Tgfb1, Il6, and Cxcl2 in lung tissues of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling. H. Flow chart of the experimental procedure for vascular endothelial cell-specific Plvap knockdown for bleomycin-induced pulmonary fibrosis. After 1 week of intratracheal drip bleomycin modeling, vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC for 21 days. The observation indexes included: lung function, HE staining, Masson staining and Sirius staining of lung tissues. I-J: Histopathological of the lungs of mice 4 weeks after bleomycin modeling, HE staining could observe signs of pulmonary fibrosis such as structural destruction of lung tissue, thickening of alveolar septa, and extensive fibrous foci, etc., and the lesions in the lungs of Plvap EC KO mice were significantly milder than those in the control group, and the histograms showed statistically significant differences in the differences. Sirius Red and Masson staining showed that the lungs of Plvap EC KO mice had Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution, and no obvious areas of fibrous occlusion were seen in the lung tissue, and the histograms showed statistically significant differences. K. Bar graphs showing lung function indices (TVb, EF50) after 4 weeks of bleomycin modeling in Plvap EC KO mice in the treatment group and in Plvap +/+ mice in the control group, and the results showed that the lung function was significantly elevated in Plvap EC KO mice. (***p<0.001, ****p<0.0001)
Step Kit Pv 6001, supplied by OriGene, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/pmc10809548-94-9-15?v=OriGene
Average 92 stars, based on 1 article reviews
step kit pv 6001 - by Bioz Stars, 2026-07
92/100 stars
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pv 9000  (OriGene)
93
OriGene pv 9000
A. Flowchart of the experiment on vascular endothelial cell-specific <t>Plvap</t> knockdown to prevent bleomycin-induced pulmonary fibrosis. Vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using the adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC, and modeled by intratracheal dropleting of bleomycin for 3 weeks 21 days after AAV injection. B. Immunofluorescence (IF) shows increased fluorescence intensity of Plvap in endothelial cells of mouse lung tissues in the Plvap +/+ group and low expression of Plvap in endothelial cells of mouse lung tissues in the Plvap EC KD group. Blue is DAPI, white <t>is</t> <t>Cd31,</t> and red is Plvap. C-D. Histopathological of the lungs of mice 4 weeks after bleomycin modeling, Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution in the lungs, and no obvious areas of fibrous occlusion were seen in the lung tissues, and the histograms showed statistically significant differences. E. Bar graphs showing lung function indexes (TVb, EF50) of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling,the results showed that the lung function of Plvap EC KO mice was significantly elevated. (*p<0.05) F. Bar graph showing the gene expression of α-SMA, Collagen I (collagen type I α 1 chain), Eln (elastin), Fn1 (fibronectin 1), Acta2, Ctgf (connective tissue growth factor) in lung tissues of preventive group of Plvap EC KO mice and control group of Plvap +/+ mice after 4 weeks of bleomycin modeling. G. Bar graph showing the gene expression of pro-fibrotic cytokines Tgfb1, Il6, and Cxcl2 in lung tissues of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling. H. Flow chart of the experimental procedure for vascular endothelial cell-specific Plvap knockdown for bleomycin-induced pulmonary fibrosis. After 1 week of intratracheal drip bleomycin modeling, vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC for 21 days. The observation indexes included: lung function, HE staining, Masson staining and Sirius staining of lung tissues. I-J: Histopathological of the lungs of mice 4 weeks after bleomycin modeling, HE staining could observe signs of pulmonary fibrosis such as structural destruction of lung tissue, thickening of alveolar septa, and extensive fibrous foci, etc., and the lesions in the lungs of Plvap EC KO mice were significantly milder than those in the control group, and the histograms showed statistically significant differences in the differences. Sirius Red and Masson staining showed that the lungs of Plvap EC KO mice had Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution, and no obvious areas of fibrous occlusion were seen in the lung tissue, and the histograms showed statistically significant differences. K. Bar graphs showing lung function indices (TVb, EF50) after 4 weeks of bleomycin modeling in Plvap EC KO mice in the treatment group and in Plvap +/+ mice in the control group, and the results showed that the lung function was significantly elevated in Plvap EC KO mice. (***p<0.001, ****p<0.0001)
Pv 9000, supplied by OriGene, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/10__4103_slash_nrr__nrr___d___23___01277-85-7-8?v=OriGene
Average 93 stars, based on 1 article reviews
pv 9000 - by Bioz Stars, 2026-07
93/100 stars
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anti plvap fitc  (Novus Biologicals)
90
Novus Biologicals anti plvap fitc
A. Flowchart of the experiment on vascular endothelial cell-specific <t>Plvap</t> knockdown to prevent bleomycin-induced pulmonary fibrosis. Vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using the adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC, and modeled by intratracheal dropleting of bleomycin for 3 weeks 21 days after AAV injection. B. Immunofluorescence (IF) shows increased fluorescence intensity of Plvap in endothelial cells of mouse lung tissues in the Plvap +/+ group and low expression of Plvap in endothelial cells of mouse lung tissues in the Plvap EC KD group. Blue is DAPI, white <t>is</t> <t>Cd31,</t> and red is Plvap. C-D. Histopathological of the lungs of mice 4 weeks after bleomycin modeling, Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution in the lungs, and no obvious areas of fibrous occlusion were seen in the lung tissues, and the histograms showed statistically significant differences. E. Bar graphs showing lung function indexes (TVb, EF50) of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling,the results showed that the lung function of Plvap EC KO mice was significantly elevated. (*p<0.05) F. Bar graph showing the gene expression of α-SMA, Collagen I (collagen type I α 1 chain), Eln (elastin), Fn1 (fibronectin 1), Acta2, Ctgf (connective tissue growth factor) in lung tissues of preventive group of Plvap EC KO mice and control group of Plvap +/+ mice after 4 weeks of bleomycin modeling. G. Bar graph showing the gene expression of pro-fibrotic cytokines Tgfb1, Il6, and Cxcl2 in lung tissues of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling. H. Flow chart of the experimental procedure for vascular endothelial cell-specific Plvap knockdown for bleomycin-induced pulmonary fibrosis. After 1 week of intratracheal drip bleomycin modeling, vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC for 21 days. The observation indexes included: lung function, HE staining, Masson staining and Sirius staining of lung tissues. I-J: Histopathological of the lungs of mice 4 weeks after bleomycin modeling, HE staining could observe signs of pulmonary fibrosis such as structural destruction of lung tissue, thickening of alveolar septa, and extensive fibrous foci, etc., and the lesions in the lungs of Plvap EC KO mice were significantly milder than those in the control group, and the histograms showed statistically significant differences in the differences. Sirius Red and Masson staining showed that the lungs of Plvap EC KO mice had Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution, and no obvious areas of fibrous occlusion were seen in the lung tissue, and the histograms showed statistically significant differences. K. Bar graphs showing lung function indices (TVb, EF50) after 4 weeks of bleomycin modeling in Plvap EC KO mice in the treatment group and in Plvap +/+ mice in the control group, and the results showed that the lung function was significantly elevated in Plvap EC KO mice. (***p<0.001, ****p<0.0001)
Anti Plvap Fitc, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/pmc07370277-150-11-15?v=Novus+Biologicals
Average 90 stars, based on 1 article reviews
anti plvap fitc - by Bioz Stars, 2026-07
90/100 stars
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plvap  (OriGene)
90
OriGene plvap
A. Flowchart of the experiment on vascular endothelial cell-specific <t>Plvap</t> knockdown to prevent bleomycin-induced pulmonary fibrosis. Vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using the adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC, and modeled by intratracheal dropleting of bleomycin for 3 weeks 21 days after AAV injection. B. Immunofluorescence (IF) shows increased fluorescence intensity of Plvap in endothelial cells of mouse lung tissues in the Plvap +/+ group and low expression of Plvap in endothelial cells of mouse lung tissues in the Plvap EC KD group. Blue is DAPI, white <t>is</t> <t>Cd31,</t> and red is Plvap. C-D. Histopathological of the lungs of mice 4 weeks after bleomycin modeling, Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution in the lungs, and no obvious areas of fibrous occlusion were seen in the lung tissues, and the histograms showed statistically significant differences. E. Bar graphs showing lung function indexes (TVb, EF50) of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling,the results showed that the lung function of Plvap EC KO mice was significantly elevated. (*p<0.05) F. Bar graph showing the gene expression of α-SMA, Collagen I (collagen type I α 1 chain), Eln (elastin), Fn1 (fibronectin 1), Acta2, Ctgf (connective tissue growth factor) in lung tissues of preventive group of Plvap EC KO mice and control group of Plvap +/+ mice after 4 weeks of bleomycin modeling. G. Bar graph showing the gene expression of pro-fibrotic cytokines Tgfb1, Il6, and Cxcl2 in lung tissues of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling. H. Flow chart of the experimental procedure for vascular endothelial cell-specific Plvap knockdown for bleomycin-induced pulmonary fibrosis. After 1 week of intratracheal drip bleomycin modeling, vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC for 21 days. The observation indexes included: lung function, HE staining, Masson staining and Sirius staining of lung tissues. I-J: Histopathological of the lungs of mice 4 weeks after bleomycin modeling, HE staining could observe signs of pulmonary fibrosis such as structural destruction of lung tissue, thickening of alveolar septa, and extensive fibrous foci, etc., and the lesions in the lungs of Plvap EC KO mice were significantly milder than those in the control group, and the histograms showed statistically significant differences in the differences. Sirius Red and Masson staining showed that the lungs of Plvap EC KO mice had Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution, and no obvious areas of fibrous occlusion were seen in the lung tissue, and the histograms showed statistically significant differences. K. Bar graphs showing lung function indices (TVb, EF50) after 4 weeks of bleomycin modeling in Plvap EC KO mice in the treatment group and in Plvap +/+ mice in the control group, and the results showed that the lung function was significantly elevated in Plvap EC KO mice. (***p<0.001, ****p<0.0001)
Plvap, supplied by OriGene, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/us11339217-616-10-12?v=OriGene
Average 90 stars, based on 1 article reviews
plvap - by Bioz Stars, 2026-07
90/100 stars
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plvap antibody  (Novus Biologicals)
91
Novus Biologicals plvap antibody
Fig. 3. DCQD ameliorated gut inflammation and gut-vascular barrier dysfunction in CCL4-induced mice. A. Hepatic FD70 and its statistics. B. Spleen FD70 and its statistics. C. Colon length and its statistics. D. Ileal sections showed immunohistochemistry for ZO-1. E. RT- qPCR showed mRNA expression of Tjp1, Ocln, and <t>Plvap.</t> F. RT-qPCR showed mRNA of Tnf, Il1b, and Il6. G. Immunofluorescence showed PV-1 (red) <t>and</t> <t>CD31</t> (green). H. Fecal SCFAs level. I. In vitro bacterial culture of the liver. J. Peripheral blood endotoxin level.
Plvap Antibody, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/pm39577253-34-56-58?v=Novus+Biologicals
Average 91 stars, based on 1 article reviews
plvap antibody - by Bioz Stars, 2026-07
91/100 stars
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monoclonal antibody  (Bio-Rad)
93
Bio-Rad monoclonal antibody
Fig. 3. DCQD ameliorated gut inflammation and gut-vascular barrier dysfunction in CCL4-induced mice. A. Hepatic FD70 and its statistics. B. Spleen FD70 and its statistics. C. Colon length and its statistics. D. Ileal sections showed immunohistochemistry for ZO-1. E. RT- qPCR showed mRNA expression of Tjp1, Ocln, and <t>Plvap.</t> F. RT-qPCR showed mRNA of Tnf, Il1b, and Il6. G. Immunofluorescence showed PV-1 (red) <t>and</t> <t>CD31</t> (green). H. Fecal SCFAs level. I. In vitro bacterial culture of the liver. J. Peripheral blood endotoxin level.
Monoclonal Antibody, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/pmc04158659-175-3-11?v=Bio-Rad
Average 93 stars, based on 1 article reviews
monoclonal antibody - by Bioz Stars, 2026-07
93/100 stars
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mouse anti pv  (Proteintech)
93
Proteintech mouse anti pv
Fig. 3. DCQD ameliorated gut inflammation and gut-vascular barrier dysfunction in CCL4-induced mice. A. Hepatic FD70 and its statistics. B. Spleen FD70 and its statistics. C. Colon length and its statistics. D. Ileal sections showed immunohistochemistry for ZO-1. E. RT- qPCR showed mRNA expression of Tjp1, Ocln, and <t>Plvap.</t> F. RT-qPCR showed mRNA of Tnf, Il1b, and Il6. G. Immunofluorescence showed PV-1 (red) <t>and</t> <t>CD31</t> (green). H. Fecal SCFAs level. I. In vitro bacterial culture of the liver. J. Peripheral blood endotoxin level.
Mouse Anti Pv, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plvap/pmc10563514-67-22-25?v=Proteintech
Average 93 stars, based on 1 article reviews
mouse anti pv - by Bioz Stars, 2026-07
93/100 stars
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rabbit anti plvap  (Atlas Antibodies)
90
Atlas Antibodies rabbit anti plvap
Fig. 3. DCQD ameliorated gut inflammation and gut-vascular barrier dysfunction in CCL4-induced mice. A. Hepatic FD70 and its statistics. B. Spleen FD70 and its statistics. C. Colon length and its statistics. D. Ileal sections showed immunohistochemistry for ZO-1. E. RT- qPCR showed mRNA expression of Tjp1, Ocln, and <t>Plvap.</t> F. RT-qPCR showed mRNA of Tnf, Il1b, and Il6. G. Immunofluorescence showed PV-1 (red) <t>and</t> <t>CD31</t> (green). H. Fecal SCFAs level. I. In vitro bacterial culture of the liver. J. Peripheral blood endotoxin level.
Rabbit Anti Plvap, supplied by Atlas Antibodies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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A. Flowchart of the experiment on vascular endothelial cell-specific Plvap knockdown to prevent bleomycin-induced pulmonary fibrosis. Vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using the adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC, and modeled by intratracheal dropleting of bleomycin for 3 weeks 21 days after AAV injection. B. Immunofluorescence (IF) shows increased fluorescence intensity of Plvap in endothelial cells of mouse lung tissues in the Plvap +/+ group and low expression of Plvap in endothelial cells of mouse lung tissues in the Plvap EC KD group. Blue is DAPI, white is Cd31, and red is Plvap. C-D. Histopathological of the lungs of mice 4 weeks after bleomycin modeling, Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution in the lungs, and no obvious areas of fibrous occlusion were seen in the lung tissues, and the histograms showed statistically significant differences. E. Bar graphs showing lung function indexes (TVb, EF50) of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling,the results showed that the lung function of Plvap EC KO mice was significantly elevated. (*p<0.05) F. Bar graph showing the gene expression of α-SMA, Collagen I (collagen type I α 1 chain), Eln (elastin), Fn1 (fibronectin 1), Acta2, Ctgf (connective tissue growth factor) in lung tissues of preventive group of Plvap EC KO mice and control group of Plvap +/+ mice after 4 weeks of bleomycin modeling. G. Bar graph showing the gene expression of pro-fibrotic cytokines Tgfb1, Il6, and Cxcl2 in lung tissues of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling. H. Flow chart of the experimental procedure for vascular endothelial cell-specific Plvap knockdown for bleomycin-induced pulmonary fibrosis. After 1 week of intratracheal drip bleomycin modeling, vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC for 21 days. The observation indexes included: lung function, HE staining, Masson staining and Sirius staining of lung tissues. I-J: Histopathological of the lungs of mice 4 weeks after bleomycin modeling, HE staining could observe signs of pulmonary fibrosis such as structural destruction of lung tissue, thickening of alveolar septa, and extensive fibrous foci, etc., and the lesions in the lungs of Plvap EC KO mice were significantly milder than those in the control group, and the histograms showed statistically significant differences in the differences. Sirius Red and Masson staining showed that the lungs of Plvap EC KO mice had Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution, and no obvious areas of fibrous occlusion were seen in the lung tissue, and the histograms showed statistically significant differences. K. Bar graphs showing lung function indices (TVb, EF50) after 4 weeks of bleomycin modeling in Plvap EC KO mice in the treatment group and in Plvap +/+ mice in the control group, and the results showed that the lung function was significantly elevated in Plvap EC KO mice. (***p<0.001, ****p<0.0001)

Journal: bioRxiv

Article Title: Regulation of Interstitial Lung Diseases by Pulmonary Endothelial Cells via PLVAP

doi: 10.1101/2024.03.12.584592

Figure Lengend Snippet: A. Flowchart of the experiment on vascular endothelial cell-specific Plvap knockdown to prevent bleomycin-induced pulmonary fibrosis. Vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using the adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC, and modeled by intratracheal dropleting of bleomycin for 3 weeks 21 days after AAV injection. B. Immunofluorescence (IF) shows increased fluorescence intensity of Plvap in endothelial cells of mouse lung tissues in the Plvap +/+ group and low expression of Plvap in endothelial cells of mouse lung tissues in the Plvap EC KD group. Blue is DAPI, white is Cd31, and red is Plvap. C-D. Histopathological of the lungs of mice 4 weeks after bleomycin modeling, Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution in the lungs, and no obvious areas of fibrous occlusion were seen in the lung tissues, and the histograms showed statistically significant differences. E. Bar graphs showing lung function indexes (TVb, EF50) of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling,the results showed that the lung function of Plvap EC KO mice was significantly elevated. (*p<0.05) F. Bar graph showing the gene expression of α-SMA, Collagen I (collagen type I α 1 chain), Eln (elastin), Fn1 (fibronectin 1), Acta2, Ctgf (connective tissue growth factor) in lung tissues of preventive group of Plvap EC KO mice and control group of Plvap +/+ mice after 4 weeks of bleomycin modeling. G. Bar graph showing the gene expression of pro-fibrotic cytokines Tgfb1, Il6, and Cxcl2 in lung tissues of Plvap EC KO mice in the prevention group and Plvap +/+ mice in the control group after 4 weeks of bleomycin modeling. H. Flow chart of the experimental procedure for vascular endothelial cell-specific Plvap knockdown for bleomycin-induced pulmonary fibrosis. After 1 week of intratracheal drip bleomycin modeling, vascular endothelial cell-specific Plvap knockdown mice (Plvap EC KO ) and control mice (Plvap +/+ ) were constructed using adeno-associated virus AAV9-ENT-ICAM2-shPlvap/AAV9-ENT-ICAM2-shNC for 21 days. The observation indexes included: lung function, HE staining, Masson staining and Sirius staining of lung tissues. I-J: Histopathological of the lungs of mice 4 weeks after bleomycin modeling, HE staining could observe signs of pulmonary fibrosis such as structural destruction of lung tissue, thickening of alveolar septa, and extensive fibrous foci, etc., and the lesions in the lungs of Plvap EC KO mice were significantly milder than those in the control group, and the histograms showed statistically significant differences in the differences. Sirius Red and Masson staining showed that the lungs of Plvap EC KO mice had Sirius Red and Masson staining showed that Plvap EC KO mice had fewer areas of collagen fiber distribution, and no obvious areas of fibrous occlusion were seen in the lung tissue, and the histograms showed statistically significant differences. K. Bar graphs showing lung function indices (TVb, EF50) after 4 weeks of bleomycin modeling in Plvap EC KO mice in the treatment group and in Plvap +/+ mice in the control group, and the results showed that the lung function was significantly elevated in Plvap EC KO mice. (***p<0.001, ****p<0.0001)

Article Snippet: Frozen sections were incubated with specific antibodies: Anti-Cd31 Antibody (BD Pharmingen™, 553370), anti-Plvap Antibody (bioss, bs-12737R).

Techniques: Knockdown, Control, Construct, Virus, Injection, Immunofluorescence, Fluorescence, Expressing, Staining

Fig. 3. DCQD ameliorated gut inflammation and gut-vascular barrier dysfunction in CCL4-induced mice. A. Hepatic FD70 and its statistics. B. Spleen FD70 and its statistics. C. Colon length and its statistics. D. Ileal sections showed immunohistochemistry for ZO-1. E. RT- qPCR showed mRNA expression of Tjp1, Ocln, and Plvap. F. RT-qPCR showed mRNA of Tnf, Il1b, and Il6. G. Immunofluorescence showed PV-1 (red) and CD31 (green). H. Fecal SCFAs level. I. In vitro bacterial culture of the liver. J. Peripheral blood endotoxin level.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Article Title: Dachengqi decoction ameliorated liver injury in liver fibrosis mice by maintaining gut vascular barrier integrity.

doi: 10.1016/j.phymed.2024.156272

Figure Lengend Snippet: Fig. 3. DCQD ameliorated gut inflammation and gut-vascular barrier dysfunction in CCL4-induced mice. A. Hepatic FD70 and its statistics. B. Spleen FD70 and its statistics. C. Colon length and its statistics. D. Ileal sections showed immunohistochemistry for ZO-1. E. RT- qPCR showed mRNA expression of Tjp1, Ocln, and Plvap. F. RT-qPCR showed mRNA of Tnf, Il1b, and Il6. G. Immunofluorescence showed PV-1 (red) and CD31 (green). H. Fecal SCFAs level. I. In vitro bacterial culture of the liver. J. Peripheral blood endotoxin level.

Article Snippet: Carbon tetrachloride (Nanjing Reagent, Cat#56–23–5); olive oil (Solarbio, Cat#IO9000); lactulose oral solution (Enulose) (Beijing Hanmi Pharmaceutical Co., National Drug Code: H20065730); FITCDextran-70 kDa (Sigma-Aldrich, Cat#60842–46–8); ESRα Rabbit mAb (ABclonal, RRID: AB_2759823); NF-κB p65 (Proteintech, RRID: AB_2178878); TNF Alpha (Proteintech, RRID: AB_2271853); Occludin antibody (Proteintech, RRID: AB_2880820); ZO-1 antibody (Proteintech, RRID: AB_10733242); β-Catenin Rabbit pAb (Abclobal, Cat#A11932); PLVAP Antibody (Novus, RRID: AB_11029033); FUT2 (9T-8) (Santa Cruz, RRID: AB_2278507); Anti-CD31 Rabbit pAb (Servicebio Cat# GB113151).

Techniques: Immunohistochemistry, Quantitative RT-PCR, Expressing, Immunofluorescence, In Vitro