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Image Search Results
Journal: bioRxiv
Article Title: Metabolic Profiling of Aortic Stenosis and Hypertrophic Cardiomyopathy Identifies Mechanistic Contrasts in Substrate Utilisation
doi: 10.1101/715680
Figure Lengend Snippet: Multivariate pairwise-analysis of patient groups. (a) PLS-DA comparison between the HCM and control groups using blood samples from all three sampling sites (CS, AR, FV) (R 2 X=36%, R 2 Y=41%, Q 2 =18%). (b) PLS-DA comparison between the AS and control groups using blood samples from all three sampling sites (CS, AR, FV) (R 2 X=38%, R 2 Y=64%, Q 2 =54%). (c) PLS-DA comparison between the HCM and AS groups using blood samples from all three sampling sites (CS, AR, FV) (R 2 X=44%, R 2 Y=70%, Q 2 =53%) (d) Random permutation test of the model validity for the model in b. (e) PLS-DA comparison between the control and AS groups using blood samples from the CS (R 2 X=30%, R 2 Y=59%, Q 2 =37%). (f) Box-whisker plots of key metabolites that are discriminatory between the AS and control groups for the model in e. (g) PLS-DA comparison between the HCM and AS groups using blood samples from the CS (R 2 X=29%, R 2 Y=47%; Q 2 =18%). (h) ROC analysis of the predictive capability of the model in e discriminating between AS and control groups.
Article Snippet: Multivariate data analysis using PCA and
Techniques: Comparison, Control, Sampling, Whisker Assay