pi103 Search Results


pi 103  (MedChemExpress)
94
MedChemExpress pi 103
Pi 103, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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pi 103  (Echelon Biosciences)
92
Echelon Biosciences pi 103
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi 103, supplied by Echelon Biosciences, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 92 stars, based on 1 article reviews
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pi 103  (Selleck Chemicals)
94
Selleck Chemicals pi 103
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi 103, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
pi 103 - by Bioz Stars, 2026-02
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pi 103 tocris 2930  (Tocris)
94
Tocris pi 103 tocris 2930
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi 103 Tocris 2930, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pi 103 tocris 2930 - by Bioz Stars, 2026-02
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pi 103 hydrochloride  (Tocris)
96
Tocris pi 103 hydrochloride
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi 103 Hydrochloride, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pi 103  (Santa Cruz Biotechnology)
91
Santa Cruz Biotechnology pi 103
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi 103, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 91 stars, based on 1 article reviews
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pi 103 hydrochloride medchemexpress  (MedChemExpress)
91
MedChemExpress pi 103 hydrochloride medchemexpress
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi 103 Hydrochloride Medchemexpress, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pi 103 hydrochloride medchemexpress - by Bioz Stars, 2026-02
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pi-103  (Wyeth Biopharma)
90
Wyeth Biopharma pi-103
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi 103, supplied by Wyeth Biopharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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sag alx-270-426-m001  (Enzo Biochem)
90
Enzo Biochem sag alx-270-426-m001
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Sag Alx 270 426 M001, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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pi-103  (Axon Medchem LLC)
90
Axon Medchem LLC pi-103
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi 103, supplied by Axon Medchem LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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pi103  (LC Laboratories)
90
LC Laboratories pi103
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi103, supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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pi103  (Merck KGaA)
90
Merck KGaA pi103
Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of <t>PI-103</t> or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.
Pi103, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of PI-103 or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.

Journal: Neuro-Oncology

Article Title: Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential anti-astrocytoma therapies

doi: 10.1093/neuonc/nor035

Figure Lengend Snippet: Inhibition of phospho-Akt (Ser473) and phospho-p70S6K (Thr389) by increasing concentrations of PI-103 or TCN (A). KR158 cells were starved and then stimulated with 10% FBS in the presence of different concentrations of PI-103 (left panels) or TCN (right panels). Growth inhibition curves as a function of drug concentration for PI-103 (B) and TCN (C). Data points are the averages of a minimum of 8 experiments with triplicate samples in each, and standard error is shown by error bars. Averaged data were used to fit the curve for each astrocytoma cell line. Murine primary astrocytes: Ms 1 Astro; murine astrocytoma grade II: K1861; murine astrocytoma grade III: KR158; murine GBM grade IV: KR130; human GBM grade IV: SF-295 and U87MG.

Article Snippet: The inhibitors tested were PI-103 (cat # B-0303, Echelon Biosciences), TCN (cat # EL-332, Biomol) and rapamycin purchased from two independent sources (cat # A-275,Biomol; cat #R-5000, LC Laboratories).

Techniques: Inhibition, Concentration Assay