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  • 95
    Millipore perfluorooctanoic acid pfoa
    Perfluorooctanoic Acid Pfoa, supplied by Millipore, used in various techniques. Bioz Stars score: 95/100, based on 40 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 95 stars, based on 40 article reviews
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    95/100 stars
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    91
    DuPont de Nemours pfoa
    Pfoa, supplied by DuPont de Nemours, used in various techniques. Bioz Stars score: 91/100, based on 59 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pfoa/product/DuPont de Nemours
    Average 91 stars, based on 59 article reviews
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    pfoa - by Bioz Stars, 2021-01
    91/100 stars
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    88
    Wellington Laboratories c4 pfoa
    C4 Pfoa, supplied by Wellington Laboratories, used in various techniques. Bioz Stars score: 88/100, based on 14 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/c4 pfoa/product/Wellington Laboratories
    Average 88 stars, based on 14 article reviews
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    85
    DuPont de Nemours c2 pfoa
    C2 Pfoa, supplied by DuPont de Nemours, used in various techniques. Bioz Stars score: 85/100, based on 9 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 85 stars, based on 9 article reviews
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    c2 pfoa - by Bioz Stars, 2021-01
    85/100 stars
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    85
    DuPont de Nemours pfoa contaminated drinking water
    Pfoa Contaminated Drinking Water, supplied by DuPont de Nemours, used in various techniques. Bioz Stars score: 85/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 85 stars, based on 3 article reviews
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    85/100 stars
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    91
    Fluka Chemical pfoa
    Pfoa, supplied by Fluka Chemical, used in various techniques. Bioz Stars score: 91/100, based on 11 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 91 stars, based on 11 article reviews
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    91/100 stars
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    99
    Thermo Fisher pfoa
    Spike raster plots illustrating the pattern of activity of a representative well of the iCell Glutaneuron – iCell Astrocytes co-culture before exposure (left) and the same well following exposure (right) to <t>PFOS</t> 10 µM ( A ) or <t>PFOA</t> 100 µM ( B ). Each row depicts one electrode in a well and each tick mark represents one spike in a 50 s interval. Spikes are depicted in black and bursts are depicted in blue.
    Pfoa, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 60 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 99 stars, based on 60 article reviews
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    91
    Wellington Laboratories pfoa
    Spike raster plots illustrating the pattern of activity of a representative well of the iCell Glutaneuron – iCell Astrocytes co-culture before exposure (left) and the same well following exposure (right) to <t>PFOS</t> 10 µM ( A ) or <t>PFOA</t> 100 µM ( B ). Each row depicts one electrode in a well and each tick mark represents one spike in a 50 s interval. Spikes are depicted in black and bursts are depicted in blue.
    Pfoa, supplied by Wellington Laboratories, used in various techniques. Bioz Stars score: 91/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pfoa/product/Wellington Laboratories
    Average 91 stars, based on 6 article reviews
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    pfoa - by Bioz Stars, 2021-01
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    91
    Wellington Laboratories 13c12 pfoa
    Spike raster plots illustrating the pattern of activity of a representative well of the iCell Glutaneuron – iCell Astrocytes co-culture before exposure (left) and the same well following exposure (right) to <t>PFOS</t> 10 µM ( A ) or <t>PFOA</t> 100 µM ( B ). Each row depicts one electrode in a well and each tick mark represents one spike in a 50 s interval. Spikes are depicted in black and bursts are depicted in blue.
    13c12 Pfoa, supplied by Wellington Laboratories, used in various techniques. Bioz Stars score: 91/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/13c12 pfoa/product/Wellington Laboratories
    Average 91 stars, based on 6 article reviews
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    13c12 pfoa - by Bioz Stars, 2021-01
    91/100 stars
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    90
    3M Co perfluorooctanoic acid pfoa
    Spike raster plots illustrating the pattern of activity of a representative well of the iCell Glutaneuron – iCell Astrocytes co-culture before exposure (left) and the same well following exposure (right) to <t>PFOS</t> 10 µM ( A ) or <t>PFOA</t> 100 µM ( B ). Each row depicts one electrode in a well and each tick mark represents one spike in a 50 s interval. Spikes are depicted in black and bursts are depicted in blue.
    Perfluorooctanoic Acid Pfoa, supplied by 3M Co, used in various techniques. Bioz Stars score: 90/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/perfluorooctanoic acid pfoa/product/3M Co
    Average 90 stars, based on 4 article reviews
    Price from $9.99 to $1999.99
    perfluorooctanoic acid pfoa - by Bioz Stars, 2021-01
    90/100 stars
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    90
    Wellington Laboratories pfoa 10 6m
    Spike raster plots illustrating the pattern of activity of a representative well of the iCell Glutaneuron – iCell Astrocytes co-culture before exposure (left) and the same well following exposure (right) to <t>PFOS</t> 10 µM ( A ) or <t>PFOA</t> 100 µM ( B ). Each row depicts one electrode in a well and each tick mark represents one spike in a 50 s interval. Spikes are depicted in black and bursts are depicted in blue.
    Pfoa 10 6m, supplied by Wellington Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 90 stars, based on 1 article reviews
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    85
    DuPont de Nemours pfoa serum
    Spike raster plots illustrating the pattern of activity of a representative well of the iCell Glutaneuron – iCell Astrocytes co-culture before exposure (left) and the same well following exposure (right) to <t>PFOS</t> 10 µM ( A ) or <t>PFOA</t> 100 µM ( B ). Each row depicts one electrode in a well and each tick mark represents one spike in a 50 s interval. Spikes are depicted in black and bursts are depicted in blue.
    Pfoa Serum, supplied by DuPont de Nemours, used in various techniques. Bioz Stars score: 85/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 85 stars, based on 4 article reviews
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    pfoa  (3M Co)
    91
    3M Co pfoa
    Predicted activation of upstream regulators in response to <t>PFOA</t> or <t>PFOS</t>
    Pfoa, supplied by 3M Co, used in various techniques. Bioz Stars score: 91/100, based on 81 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 91 stars, based on 81 article reviews
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    91
    TCI Tokyo Chemical Industry pfoa
    Predicted activation of upstream regulators in response to <t>PFOA</t> or <t>PFOS</t>
    Pfoa, supplied by TCI Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 91/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pfoa/product/TCI Tokyo Chemical Industry
    Average 91 stars, based on 5 article reviews
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    92
    DuPont de Nemours 2009 pfoa risk assessment
    Predicted activation of upstream regulators in response to <t>PFOA</t> or <t>PFOS</t>
    2009 Pfoa Risk Assessment, supplied by DuPont de Nemours, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 92 stars, based on 2 article reviews
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    85
    DuPont de Nemours perfluorooctanoate pfoa
    Predicted activation of upstream regulators in response to <t>PFOA</t> or <t>PFOS</t>
    Perfluorooctanoate Pfoa, supplied by DuPont de Nemours, used in various techniques. Bioz Stars score: 85/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    88
    TCI Tokyo Chemical Industry perfluorooctanoic acid pfoa
    Predicted activation of upstream regulators in response to <t>PFOA</t> or <t>PFOS</t>
    Perfluorooctanoic Acid Pfoa, supplied by TCI Tokyo Chemical Industry, used in various techniques. Bioz Stars score: 88/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    91
    Wellington Laboratories c2 perfluoro n octanoic acid pfoa
    Predicted activation of upstream regulators in response to <t>PFOA</t> or <t>PFOS</t>
    C2 Perfluoro N Octanoic Acid Pfoa, supplied by Wellington Laboratories, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/c2 perfluoro n octanoic acid pfoa/product/Wellington Laboratories
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    95
    Millipore reagents pfoa
    Predicted activation of upstream regulators in response to <t>PFOA</t> or <t>PFOS</t>
    Reagents Pfoa, supplied by Millipore, used in various techniques. Bioz Stars score: 95/100, based on 4 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 95 stars, based on 4 article reviews
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    85
    DuPont de Nemours drinking water pfoa
    Predicted activation of upstream regulators in response to <t>PFOA</t> or <t>PFOS</t>
    Drinking Water Pfoa, supplied by DuPont de Nemours, used in various techniques. Bioz Stars score: 85/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/drinking water pfoa/product/DuPont de Nemours
    Average 85 stars, based on 2 article reviews
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    drinking water pfoa - by Bioz Stars, 2021-01
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    Image Search Results


    Spike raster plots illustrating the pattern of activity of a representative well of the iCell Glutaneuron – iCell Astrocytes co-culture before exposure (left) and the same well following exposure (right) to PFOS 10 µM ( A ) or PFOA 100 µM ( B ). Each row depicts one electrode in a well and each tick mark represents one spike in a 50 s interval. Spikes are depicted in black and bursts are depicted in blue.

    Journal: Scientific Reports

    Article Title: Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) acutely affect human α1β2γ2L GABAA receptor and spontaneous neuronal network function in vitro

    doi: 10.1038/s41598-020-62152-2

    Figure Lengend Snippet: Spike raster plots illustrating the pattern of activity of a representative well of the iCell Glutaneuron – iCell Astrocytes co-culture before exposure (left) and the same well following exposure (right) to PFOS 10 µM ( A ) or PFOA 100 µM ( B ). Each row depicts one electrode in a well and each tick mark represents one spike in a 50 s interval. Spikes are depicted in black and bursts are depicted in blue.

    Article Snippet: Stock solutions of PFOS ( > 98% purity, Fluka, Zwijndrecht, The Netherlands) and PFOA ( > 96% purity, Acros Organics, Geel, Belgium) were made in purity-checked dimethyl sulfoxide (DMSO) and stored at 4 °C.

    Techniques: Activity Assay, Co-Culture Assay

    Modulation of spontaneous neuronal activity of rat primary cortical neurons exposed to PFOS (black) or PFOA (grey) following acute exposure. Effects on mean spike rate (MSR; A ), mean burst rate (MBR; B ), mean network burst rate (MNBR; C ), burst duration ( D ) and network burst duration ( E ) are depicted as average in % change of control (solvent control set to 100%; dashed line) ± SEM from n = 18–20 wells and N = 4 plates. *Indicates p

    Journal: Scientific Reports

    Article Title: Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) acutely affect human α1β2γ2L GABAA receptor and spontaneous neuronal network function in vitro

    doi: 10.1038/s41598-020-62152-2

    Figure Lengend Snippet: Modulation of spontaneous neuronal activity of rat primary cortical neurons exposed to PFOS (black) or PFOA (grey) following acute exposure. Effects on mean spike rate (MSR; A ), mean burst rate (MBR; B ), mean network burst rate (MNBR; C ), burst duration ( D ) and network burst duration ( E ) are depicted as average in % change of control (solvent control set to 100%; dashed line) ± SEM from n = 18–20 wells and N = 4 plates. *Indicates p

    Article Snippet: Stock solutions of PFOS ( > 98% purity, Fluka, Zwijndrecht, The Netherlands) and PFOA ( > 96% purity, Acros Organics, Geel, Belgium) were made in purity-checked dimethyl sulfoxide (DMSO) and stored at 4 °C.

    Techniques: Activity Assay

    Modulation of spontaneous neuronal activity of iCell Glutaneuron – iCell Astrocytes co-culture exposed to PFOS (black) or PFOA (grey) following acute exposure. Effects on mean spike rate (MSR; A ), mean burst rate (MBR; B ), mean network burst rate (MNBR; C ), burst duration ( D ) and network burst duration ( E ) are depicted as average in % change of control (solvent control set to 100%; dashed line) ± SEM from n = 3–17 wells and N = 3–5 plates. *Indicates p

    Journal: Scientific Reports

    Article Title: Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) acutely affect human α1β2γ2L GABAA receptor and spontaneous neuronal network function in vitro

    doi: 10.1038/s41598-020-62152-2

    Figure Lengend Snippet: Modulation of spontaneous neuronal activity of iCell Glutaneuron – iCell Astrocytes co-culture exposed to PFOS (black) or PFOA (grey) following acute exposure. Effects on mean spike rate (MSR; A ), mean burst rate (MBR; B ), mean network burst rate (MNBR; C ), burst duration ( D ) and network burst duration ( E ) are depicted as average in % change of control (solvent control set to 100%; dashed line) ± SEM from n = 3–17 wells and N = 3–5 plates. *Indicates p

    Article Snippet: Stock solutions of PFOS ( > 98% purity, Fluka, Zwijndrecht, The Netherlands) and PFOA ( > 96% purity, Acros Organics, Geel, Belgium) were made in purity-checked dimethyl sulfoxide (DMSO) and stored at 4 °C.

    Techniques: Activity Assay, Co-Culture Assay

    Modulation of spontaneous neuronal activity of SynFire iNS co-culture with PFOS (black) or PFOA (grey). Effects on mean spike rate (MSR; A ), mean burst rate (MBR; B ), mean network burst rate (MNBR; C ), burst duration ( D ) and network burst duration ( E ) are depicted as average in % change of control (solvent control set to 100%; dashed line) ± SEM from n = 7–9 wells and N = 2 plates. *Indicates p

    Journal: Scientific Reports

    Article Title: Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) acutely affect human α1β2γ2L GABAA receptor and spontaneous neuronal network function in vitro

    doi: 10.1038/s41598-020-62152-2

    Figure Lengend Snippet: Modulation of spontaneous neuronal activity of SynFire iNS co-culture with PFOS (black) or PFOA (grey). Effects on mean spike rate (MSR; A ), mean burst rate (MBR; B ), mean network burst rate (MNBR; C ), burst duration ( D ) and network burst duration ( E ) are depicted as average in % change of control (solvent control set to 100%; dashed line) ± SEM from n = 7–9 wells and N = 2 plates. *Indicates p

    Article Snippet: Stock solutions of PFOS ( > 98% purity, Fluka, Zwijndrecht, The Netherlands) and PFOA ( > 96% purity, Acros Organics, Geel, Belgium) were made in purity-checked dimethyl sulfoxide (DMSO) and stored at 4 °C.

    Techniques: Activity Assay, Co-Culture Assay

    Antagonistic effects of PFOS and PFOA on the human GABA A receptor. Example recordings of inhibition of GABA-evoked ion currents by co-application of PFOS (1 µM, a , c ) or PFOA (10 µM, b , d ) with GABA (at low and high effective GABA concentration, respectively). PFOS-induced inhibition is poorly reversible ( a , c ), whereas PFOA-induced inhibition is reversed within seconds ( b , d ). Scale bar applies to all traces. Concentration-response curves show the concentration-dependent inhibition of GABA-evoked responses by PFOS ( e ) and PFOA ( f ) on the human GAB A receptor with at low ( e , f ; solid line) and high ( e,f ; dashed line) effective GABA concentrations. Inhibition is presented as percentage of the GABA-evoked response (mean ± SEM, n = 3–4 oocytes per concentration from N = 1–2 batches).

    Journal: Scientific Reports

    Article Title: Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) acutely affect human α1β2γ2L GABAA receptor and spontaneous neuronal network function in vitro

    doi: 10.1038/s41598-020-62152-2

    Figure Lengend Snippet: Antagonistic effects of PFOS and PFOA on the human GABA A receptor. Example recordings of inhibition of GABA-evoked ion currents by co-application of PFOS (1 µM, a , c ) or PFOA (10 µM, b , d ) with GABA (at low and high effective GABA concentration, respectively). PFOS-induced inhibition is poorly reversible ( a , c ), whereas PFOA-induced inhibition is reversed within seconds ( b , d ). Scale bar applies to all traces. Concentration-response curves show the concentration-dependent inhibition of GABA-evoked responses by PFOS ( e ) and PFOA ( f ) on the human GAB A receptor with at low ( e , f ; solid line) and high ( e,f ; dashed line) effective GABA concentrations. Inhibition is presented as percentage of the GABA-evoked response (mean ± SEM, n = 3–4 oocytes per concentration from N = 1–2 batches).

    Article Snippet: Stock solutions of PFOS ( > 98% purity, Fluka, Zwijndrecht, The Netherlands) and PFOA ( > 96% purity, Acros Organics, Geel, Belgium) were made in purity-checked dimethyl sulfoxide (DMSO) and stored at 4 °C.

    Techniques: Inhibition, Concentration Assay

    Heatmap of the effects of PFOS (light green) and PFOA (darker green) on selected metric parameters on rat primary cortical neurons (top; grey), iCell Glutaneuron – iCell Astrocytes (middle; black) and SynFire iNS co-culture (bottom; green). Colour scaling is based on the magnitude change in percentages relative to vehicle control based on n = 18–20 wells and N = 4 plates for rat primary cortical neurons; n = 3–17 wells and N = 3–5 plates for iCell Glutaneuron – iCell Astrocytes; n = 6–9 wells N = 2 plates for SynFire iNS co-culture.

    Journal: Scientific Reports

    Article Title: Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) acutely affect human α1β2γ2L GABAA receptor and spontaneous neuronal network function in vitro

    doi: 10.1038/s41598-020-62152-2

    Figure Lengend Snippet: Heatmap of the effects of PFOS (light green) and PFOA (darker green) on selected metric parameters on rat primary cortical neurons (top; grey), iCell Glutaneuron – iCell Astrocytes (middle; black) and SynFire iNS co-culture (bottom; green). Colour scaling is based on the magnitude change in percentages relative to vehicle control based on n = 18–20 wells and N = 4 plates for rat primary cortical neurons; n = 3–17 wells and N = 3–5 plates for iCell Glutaneuron – iCell Astrocytes; n = 6–9 wells N = 2 plates for SynFire iNS co-culture.

    Article Snippet: Stock solutions of PFOS ( > 98% purity, Fluka, Zwijndrecht, The Netherlands) and PFOA ( > 96% purity, Acros Organics, Geel, Belgium) were made in purity-checked dimethyl sulfoxide (DMSO) and stored at 4 °C.

    Techniques: Co-Culture Assay

    Predicted activation of upstream regulators in response to PFOA or PFOS

    Journal: Toxicology and applied pharmacology

    Article Title: The Role of Hepatocyte Nuclear Factor 4-Alpha in Perfluorooctanoic Acid- and Perfluorooctanesulfonic Acid-Induced Hepatocellular Dysfunction

    doi: 10.1016/j.taap.2016.05.001

    Figure Lengend Snippet: Predicted activation of upstream regulators in response to PFOA or PFOS

    Article Snippet: As expected, residents of the areas surrounding cities including Decatur, Alabama and Cottage Grove, Minnesota, where the 3M company manufactured PFOA and PFOS, had higher concentrations in their blood, as a consequence of watershed contamination.

    Techniques: Activation Assay

    In silico docking studies of PFOA and PFOS to HNF4α

    Journal: Toxicology and applied pharmacology

    Article Title: The Role of Hepatocyte Nuclear Factor 4-Alpha in Perfluorooctanoic Acid- and Perfluorooctanesulfonic Acid-Induced Hepatocellular Dysfunction

    doi: 10.1016/j.taap.2016.05.001

    Figure Lengend Snippet: In silico docking studies of PFOA and PFOS to HNF4α

    Article Snippet: As expected, residents of the areas surrounding cities including Decatur, Alabama and Cottage Grove, Minnesota, where the 3M company manufactured PFOA and PFOS, had higher concentrations in their blood, as a consequence of watershed contamination.

    Techniques: In Silico

    Genes upregulated by PFOA or PFOS and NANOG expression

    Journal: Toxicology and applied pharmacology

    Article Title: The Role of Hepatocyte Nuclear Factor 4-Alpha in Perfluorooctanoic Acid- and Perfluorooctanesulfonic Acid-Induced Hepatocellular Dysfunction

    doi: 10.1016/j.taap.2016.05.001

    Figure Lengend Snippet: Genes upregulated by PFOA or PFOS and NANOG expression

    Article Snippet: As expected, residents of the areas surrounding cities including Decatur, Alabama and Cottage Grove, Minnesota, where the 3M company manufactured PFOA and PFOS, had higher concentrations in their blood, as a consequence of watershed contamination.

    Techniques: Expressing

    HNF4α regulated genes altered in response to PFOA and PFOS

    Journal: Toxicology and applied pharmacology

    Article Title: The Role of Hepatocyte Nuclear Factor 4-Alpha in Perfluorooctanoic Acid- and Perfluorooctanesulfonic Acid-Induced Hepatocellular Dysfunction

    doi: 10.1016/j.taap.2016.05.001

    Figure Lengend Snippet: HNF4α regulated genes altered in response to PFOA and PFOS

    Article Snippet: As expected, residents of the areas surrounding cities including Decatur, Alabama and Cottage Grove, Minnesota, where the 3M company manufactured PFOA and PFOS, had higher concentrations in their blood, as a consequence of watershed contamination.

    Techniques:

    PFOA- and PFOS-induced cytotoxicity

    Journal: Toxicology and applied pharmacology

    Article Title: The Role of Hepatocyte Nuclear Factor 4-Alpha in Perfluorooctanoic Acid- and Perfluorooctanesulfonic Acid-Induced Hepatocellular Dysfunction

    doi: 10.1016/j.taap.2016.05.001

    Figure Lengend Snippet: PFOA- and PFOS-induced cytotoxicity

    Article Snippet: As expected, residents of the areas surrounding cities including Decatur, Alabama and Cottage Grove, Minnesota, where the 3M company manufactured PFOA and PFOS, had higher concentrations in their blood, as a consequence of watershed contamination.

    Techniques:

    Human serum concentrations of PFOA and PFOS within different subpopulations of exposure in the United States

    Journal: Toxicology and applied pharmacology

    Article Title: The Role of Hepatocyte Nuclear Factor 4-Alpha in Perfluorooctanoic Acid- and Perfluorooctanesulfonic Acid-Induced Hepatocellular Dysfunction

    doi: 10.1016/j.taap.2016.05.001

    Figure Lengend Snippet: Human serum concentrations of PFOA and PFOS within different subpopulations of exposure in the United States

    Article Snippet: As expected, residents of the areas surrounding cities including Decatur, Alabama and Cottage Grove, Minnesota, where the 3M company manufactured PFOA and PFOS, had higher concentrations in their blood, as a consequence of watershed contamination.

    Techniques:

    Genes downregulated by PFOA or PFOS

    Journal: Toxicology and applied pharmacology

    Article Title: The Role of Hepatocyte Nuclear Factor 4-Alpha in Perfluorooctanoic Acid- and Perfluorooctanesulfonic Acid-Induced Hepatocellular Dysfunction

    doi: 10.1016/j.taap.2016.05.001

    Figure Lengend Snippet: Genes downregulated by PFOA or PFOS

    Article Snippet: As expected, residents of the areas surrounding cities including Decatur, Alabama and Cottage Grove, Minnesota, where the 3M company manufactured PFOA and PFOS, had higher concentrations in their blood, as a consequence of watershed contamination.

    Techniques:

    PFOA and PFOS ligands docked to HNF4α

    Journal: Toxicology and applied pharmacology

    Article Title: The Role of Hepatocyte Nuclear Factor 4-Alpha in Perfluorooctanoic Acid- and Perfluorooctanesulfonic Acid-Induced Hepatocellular Dysfunction

    doi: 10.1016/j.taap.2016.05.001

    Figure Lengend Snippet: PFOA and PFOS ligands docked to HNF4α

    Article Snippet: As expected, residents of the areas surrounding cities including Decatur, Alabama and Cottage Grove, Minnesota, where the 3M company manufactured PFOA and PFOS, had higher concentrations in their blood, as a consequence of watershed contamination.

    Techniques:

    Concentration-response of HNF4α protein expression in hepatocytes exposed to PFOA or PFOS

    Journal: Toxicology and applied pharmacology

    Article Title: The Role of Hepatocyte Nuclear Factor 4-Alpha in Perfluorooctanoic Acid- and Perfluorooctanesulfonic Acid-Induced Hepatocellular Dysfunction

    doi: 10.1016/j.taap.2016.05.001

    Figure Lengend Snippet: Concentration-response of HNF4α protein expression in hepatocytes exposed to PFOA or PFOS

    Article Snippet: As expected, residents of the areas surrounding cities including Decatur, Alabama and Cottage Grove, Minnesota, where the 3M company manufactured PFOA and PFOS, had higher concentrations in their blood, as a consequence of watershed contamination.

    Techniques: Concentration Assay, Expressing