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Image Search Results
Journal: Clinical & Translational Immunology
Article Title: Distinct macrophage phenotypes skewed by local granulocyte macrophage colony‐stimulating factor (GM‐CSF) and macrophage colony‐stimulating factor (M‐CSF) are associated with tissue destruction and intimal hyperplasia in giant cell arteritis
doi: 10.1002/cti2.1164
Figure Lengend Snippet: FRβ + positivity in the inner intima is associated with high‐degree intimal hyperplasia. Classification of mildly and massively occluded TAB based on the thickness of intima (a) . The Mann–Whitney U ‐test showed significantly higher expression of FRβ in the inner intima of TABs with massive intimal hyperplasia (mild occlusion n = 6; massive occlusion n = 5) (b) . The Wilcoxon signed‐rank test showed higher expression of PDGF‐AA in M‐MØ compared to GM‐MØ ( n = 10 each, ELISA was performed in duplicates for each sample) (c) . GCA, giant cell arteritis; GM‐MØ, GM‐CSF macrophages; M‐MØ, M‐CSF macrophages; TAB, temporal artery biopsy.
Article Snippet: PDGF‐AA concentrations in the supernatant of activated cultures were measured with the
Techniques: MANN-WHITNEY, Expressing, Enzyme-linked Immunosorbent Assay