paxillin Search Results


paxilline  (Alomone Labs)
94
Alomone Labs paxilline
Paxilline, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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paxilline  (Tocris)
99
Tocris paxilline
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
Paxilline, supplied by Tocris, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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vasp mturquoise  (Addgene inc)
92
Addgene inc vasp mturquoise
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
Vasp Mturquoise, supplied by Addgene inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti phospho paxillin  (ECM Biosciences)
90
ECM Biosciences anti phospho paxillin
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
Anti Phospho Paxillin, supplied by ECM Biosciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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phospho paxillin ps178  (ECM Biosciences)
90
ECM Biosciences phospho paxillin ps178
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
Phospho Paxillin Ps178, supplied by ECM Biosciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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paxillin  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc paxillin
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
Paxillin, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/paxillin/Paxillin+Antibody/10__1074_slash_mcp__m115__050484-45-14-37
Average 96 stars, based on 1 article reviews
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rabbit α mouse phospho paxillin tyr118  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc rabbit α mouse phospho paxillin tyr118
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
Rabbit α Mouse Phospho Paxillin Tyr118, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/paxillin/Phospho-Paxillin+(Tyr118)+Antibody/10__7554_slash_elife__96810-295-29-49
Average 96 stars, based on 1 article reviews
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p paxillin y118  (Cell Signaling Technology Inc)
94
Cell Signaling Technology Inc p paxillin y118
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
P Paxillin Y118, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/paxillin/Phospho-Paxillin+(Tyr118)+Rabbit+mAb/pmc10398415-66-70-79
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full length paxillin egfp  (Addgene inc)
93
Addgene inc full length paxillin egfp
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
Full Length Paxillin Egfp, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mcherry paxillin 22  (Addgene inc)
91
Addgene inc mcherry paxillin 22
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
Mcherry Paxillin 22, supplied by Addgene inc, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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memerald paxillin  (Addgene inc)
92
Addgene inc memerald paxillin
Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L <t>paxilline,</t> a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K
Memerald Paxillin, supplied by Addgene inc, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L paxilline, a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K

Journal: Circulation Research

Article Title: H 2 O 2 -Induced Dilation in Human Coronary Arterioles: Role of Protein Kinase G Dimerization and Large-Conductance Ca 2+ -Activated K + Channel Activation

doi: 10.1161/circresaha.111.258871

Figure Lengend Snippet: Figure 4. Expression of BKCa channels in coronary smooth muscle cells. A, Expression of BKCa channel -subunits was detected at mRNA level in freshly isolated SMCs from patients with and without CAD, as indicated by a represen- tative image of reverse transcription- polymerase chain reaction analysis. B, BKCa -subunit protein was expressed in coronary arterioles from patients with (patient number in black) and without CAD (patient number in gray). Lower, summarized data; n8 and 9 for CAD and non CAD, respectively. C, Presence of BKCa channel -subunit protein (green) is confirmed with immunocytochemistry using freshly dispersed SMCs. Cell nuclei are stained in blue. Scale bar20 m. Data are representative of 3 independent experiments with 5 to 10 cells/group/ex- periment. D, In inside-out patches of freshly isolated SMCs from human coro- nary arterioles, an increase in membrane potential enhanced BKCa channel open probability (left) that was abolished by 100 nmol/L paxilline, a specific BKCa channel inhibitor. The current–voltage relationship revealed a unitary conduc- tance of 246 pS with a reversal potential of 0 mV in symmetrical (145 mmol/L) K

Article Snippet: Spermine NONOate was obtained from Cayman Chemical Company, paxilline from Tocris, and DT-2 from Axxora.

Techniques: Expressing, Isolation, Reverse Transcription, Polymerase Chain Reaction, Immunocytochemistry, Staining, Membrane

Figure 5. Effect of H2O2 on BKCa chan- nel currents in freshly isolated coro- nary arteriolar smooth muscle cells. Using cell-attached patches (A), H2O2 (50 mol/L) increased BKCa single- channel currents in a paxilline (100 nmol/L)- sensitive fashion. However, H2O2-induced BKCa activation was greatly diminished in single-channel recordings from inside-out patches which lack intracellular constitu- ents (B). H2O2-activated BKCa single- channel currents recorded from cell- attached patches were reduced in the presence of 10 mol/L DT-2, a PKG-I inhibitor (C). Note that c, closed state; PP, patch potential; n6 to 12 patches/ each group. *P0.05 versus control. #P0.05 versus H2O2.

Journal: Circulation Research

Article Title: H 2 O 2 -Induced Dilation in Human Coronary Arterioles: Role of Protein Kinase G Dimerization and Large-Conductance Ca 2+ -Activated K + Channel Activation

doi: 10.1161/circresaha.111.258871

Figure Lengend Snippet: Figure 5. Effect of H2O2 on BKCa chan- nel currents in freshly isolated coro- nary arteriolar smooth muscle cells. Using cell-attached patches (A), H2O2 (50 mol/L) increased BKCa single- channel currents in a paxilline (100 nmol/L)- sensitive fashion. However, H2O2-induced BKCa activation was greatly diminished in single-channel recordings from inside-out patches which lack intracellular constitu- ents (B). H2O2-activated BKCa single- channel currents recorded from cell- attached patches were reduced in the presence of 10 mol/L DT-2, a PKG-I inhibitor (C). Note that c, closed state; PP, patch potential; n6 to 12 patches/ each group. *P0.05 versus control. #P0.05 versus H2O2.

Article Snippet: Spermine NONOate was obtained from Cayman Chemical Company, paxilline from Tocris, and DT-2 from Axxora.

Techniques: Isolation, Activation Assay, Control