organoplate 2 lane chip Search Results


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    Mimetas Inc organoplate 2 lane chip
    (A) . Image and representative diagram of the 2-lane OrganoPlate. Boxes 1, 2 and 4 mark where reagents/cells can be added to the respective parts of the chip. x and y -axes show the chip orientation on the plate; (B) . Rocker with plate and diagrammatic representation of the direction and gradient of media flow; (C) . Diagrammatic representation of the formation of the cell layer following seeding of the human coronary artery endothelial cells (HCAECs) (cells shown in white) within the 2-lane OrganoPlate. Red areas represent the perfusion channel, blue areas the extracellular matrix (ECM) and grey the plate PhaseGuide. Bidirectional arrows represent the direction of flow and x and y -axes the orientation; g = gravity. (D) . Diagrammatic representation of the cell culture within the OrganoPlate 2-lane. The arrow represents the bidirectional flow of medium/suspension cells; green circles represent THP-1 cells; the endothelial cell vessel is represented in red and the extracellular collagen matrix in blue; (E) . Image of the 3D HCAEC vessel stained with CD31.
    Organoplate 2 Lane Chip, supplied by Mimetas Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/organoplate 2 lane chip/product/Mimetas Inc
    Average 86 stars, based on 1 article reviews
    Price from $9.99 to $1999.99
    organoplate 2 lane chip - by Bioz Stars, 2024-10
    86/100 stars
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    Image Search Results


    (A) . Image and representative diagram of the 2-lane OrganoPlate. Boxes 1, 2 and 4 mark where reagents/cells can be added to the respective parts of the chip. x and y -axes show the chip orientation on the plate; (B) . Rocker with plate and diagrammatic representation of the direction and gradient of media flow; (C) . Diagrammatic representation of the formation of the cell layer following seeding of the human coronary artery endothelial cells (HCAECs) (cells shown in white) within the 2-lane OrganoPlate. Red areas represent the perfusion channel, blue areas the extracellular matrix (ECM) and grey the plate PhaseGuide. Bidirectional arrows represent the direction of flow and x and y -axes the orientation; g = gravity. (D) . Diagrammatic representation of the cell culture within the OrganoPlate 2-lane. The arrow represents the bidirectional flow of medium/suspension cells; green circles represent THP-1 cells; the endothelial cell vessel is represented in red and the extracellular collagen matrix in blue; (E) . Image of the 3D HCAEC vessel stained with CD31.

    Journal: Frontiers in Toxicology

    Article Title: Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

    doi: 10.3389/ftox.2024.1395670

    Figure Lengend Snippet: (A) . Image and representative diagram of the 2-lane OrganoPlate. Boxes 1, 2 and 4 mark where reagents/cells can be added to the respective parts of the chip. x and y -axes show the chip orientation on the plate; (B) . Rocker with plate and diagrammatic representation of the direction and gradient of media flow; (C) . Diagrammatic representation of the formation of the cell layer following seeding of the human coronary artery endothelial cells (HCAECs) (cells shown in white) within the 2-lane OrganoPlate. Red areas represent the perfusion channel, blue areas the extracellular matrix (ECM) and grey the plate PhaseGuide. Bidirectional arrows represent the direction of flow and x and y -axes the orientation; g = gravity. (D) . Diagrammatic representation of the cell culture within the OrganoPlate 2-lane. The arrow represents the bidirectional flow of medium/suspension cells; green circles represent THP-1 cells; the endothelial cell vessel is represented in red and the extracellular collagen matrix in blue; (E) . Image of the 3D HCAEC vessel stained with CD31.

    Article Snippet: Human Coronary Artery Endothelial Cells (HCAECs) were cultured on an OrganoPlate ® 2-lane chip (Mimetas BV) combined with THP-1 monocytes under flow conditions.

    Techniques: Cell Culture, Suspension, Staining