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  • 99
    Millipore l cysteine
    L Cysteine, supplied by Millipore, used in various techniques. Bioz Stars score: 99/100, based on 3331 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    99
    Millipore 4 oh tamoxifen
    Increased Sirt1 expression protects from non‐small cell lung carcinoma in mice and humans A Kaplan–Meier survival curve of mice of the indicated genotypes injected with <t>4‐OH</t> <t>tamoxifen</t> at 2‐3 months of age. B Kaplan–Meier survival curve of mice from (A) censoring for tumor appearance by μCT scanner. C, D Quantification of the number of adenomas (C) and carcinomas (D) per mouse at the time of death by histopathological analysis. E Follow‐up of tumor sizes by periodical μCT scanner, starting from the time point when the tumor was first detected. F, G (F) Kaplan–Meier curve indicating that lung tumors (including all tumors in the TMA, n = 105) displaying high expression of cytoplasmic SIRT1 (at least 20% of their neoplastic cells positive for SIRT1) show longer progression‐free survival time (*** P
    4 Oh Tamoxifen, supplied by Millipore, used in various techniques. Bioz Stars score: 99/100, based on 1000 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    92
    Waters Corporation oh d3
    Increased Sirt1 expression protects from non‐small cell lung carcinoma in mice and humans A Kaplan–Meier survival curve of mice of the indicated genotypes injected with <t>4‐OH</t> <t>tamoxifen</t> at 2‐3 months of age. B Kaplan–Meier survival curve of mice from (A) censoring for tumor appearance by μCT scanner. C, D Quantification of the number of adenomas (C) and carcinomas (D) per mouse at the time of death by histopathological analysis. E Follow‐up of tumor sizes by periodical μCT scanner, starting from the time point when the tumor was first detected. F, G (F) Kaplan–Meier curve indicating that lung tumors (including all tumors in the TMA, n = 105) displaying high expression of cytoplasmic SIRT1 (at least 20% of their neoplastic cells positive for SIRT1) show longer progression‐free survival time (*** P
    Oh D3, supplied by Waters Corporation, used in various techniques. Bioz Stars score: 92/100, based on 169 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    91
    DiaSorin liaison 25 oh vitamin d total assay
    ADVIA Centaur® <t>Vitamin</t> D <t>Total</t>
    Liaison 25 Oh Vitamin D Total Assay, supplied by DiaSorin, used in various techniques. Bioz Stars score: 91/100, based on 205 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    92
    Tocris 8 oh dpat
    Inhibitory receptor blockers occluded the <t>8-OH-DPAT-induced</t> excitation in Lmx1b f/f/p slice preparations. Hypoglossal burst frequency at baseline, during application of an inhibitory blocker mixture consisting of gabazine (0.5 μ m ), CGP 55845 (1
    8 Oh Dpat, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 118 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    91
    Cayman Chemical 1 25 oh 2 d3
    Inhibitory receptor blockers occluded the <t>8-OH-DPAT-induced</t> excitation in Lmx1b f/f/p slice preparations. Hypoglossal burst frequency at baseline, during application of an inhibitory blocker mixture consisting of gabazine (0.5 μ m ), CGP 55845 (1
    1 25 Oh 2 D3, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    92
    DiaSorin oh d3
    Inhibitory receptor blockers occluded the <t>8-OH-DPAT-induced</t> excitation in Lmx1b f/f/p slice preparations. Hypoglossal burst frequency at baseline, during application of an inhibitory blocker mixture consisting of gabazine (0.5 μ m ), CGP 55845 (1
    Oh D3, supplied by DiaSorin, used in various techniques. Bioz Stars score: 92/100, based on 100 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    90
    DiaSorin 25 oh vitamin d
    Associations between serum total 25‐ OH <t>vitamin</t> D quintile and mortality. Median 25‐ OH vitamin D is shown for each quintile. Demographic risk factors were age and sex. Clinical risk factors were body mass index, smoking status (current, prior vs never), renal disease, hypertension, hyperlipidemia, type 2 diabetes mellitus, family history of heart disease, prior myocardial infarction, congestive heart failure, whether ejection fraction was measured, ejection fraction (
    25 Oh Vitamin D, supplied by DiaSorin, used in various techniques. Bioz Stars score: 90/100, based on 65 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    98
    Millipore fmoc lys boc oh
    Associations between serum total 25‐ OH <t>vitamin</t> D quintile and mortality. Median 25‐ OH vitamin D is shown for each quintile. Demographic risk factors were age and sex. Clinical risk factors were body mass index, smoking status (current, prior vs never), renal disease, hypertension, hyperlipidemia, type 2 diabetes mellitus, family history of heart disease, prior myocardial infarction, congestive heart failure, whether ejection fraction was measured, ejection fraction (
    Fmoc Lys Boc Oh, supplied by Millipore, used in various techniques. Bioz Stars score: 98/100, based on 66 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    95
    Millipore fmoc gly oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Fmoc Gly Oh, supplied by Millipore, used in various techniques. Bioz Stars score: 95/100, based on 86 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    91
    DSM NV oh d3
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Oh D3, supplied by DSM NV, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    92
    Fisher Scientific nh4 oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Nh4 Oh, supplied by Fisher Scientific, used in various techniques. Bioz Stars score: 92/100, based on 48 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    99
    Millipore fmoc arg pbf oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Fmoc Arg Pbf Oh, supplied by Millipore, used in various techniques. Bioz Stars score: 99/100, based on 62 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    93
    Agilent technologies oh d3
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Oh D3, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 93/100, based on 64 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    93
    Merck & Co nh4 oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Nh4 Oh, supplied by Merck & Co, used in various techniques. Bioz Stars score: 93/100, based on 77 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    94
    Cambridge Isotope Laboratories nh2 oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Nh2 Oh, supplied by Cambridge Isotope Laboratories, used in various techniques. Bioz Stars score: 94/100, based on 32 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    90
    Santa Cruz Biotechnology oh d3
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Oh D3, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 34 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    90
    Merck & Co chcl3 ch3 oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Chcl3 Ch3 Oh, supplied by Merck & Co, used in various techniques. Bioz Stars score: 90/100, based on 90 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    84
    Diasource free 25 oh d
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Free 25 Oh D, supplied by Diasource, used in various techniques. Bioz Stars score: 84/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    96
    Millipore fmoc cys trt oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Fmoc Cys Trt Oh, supplied by Millipore, used in various techniques. Bioz Stars score: 96/100, based on 76 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    88
    Johnson & Johnson oh jj
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Oh Jj, supplied by Johnson & Johnson, used in various techniques. Bioz Stars score: 88/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    91
    Tanabe ryu oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Ryu Oh, supplied by Tanabe, used in various techniques. Bioz Stars score: 91/100, based on 30 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    99
    Millipore nh4 oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Nh4 Oh, supplied by Millipore, used in various techniques. Bioz Stars score: 99/100, based on 570 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    93
    Millipore fmoc ala oh
    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) <t>Fmoc-Gly-OH,</t> HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.
    Fmoc Ala Oh, supplied by Millipore, used in various techniques. Bioz Stars score: 93/100, based on 22 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    Increased Sirt1 expression protects from non‐small cell lung carcinoma in mice and humans A Kaplan–Meier survival curve of mice of the indicated genotypes injected with 4‐OH tamoxifen at 2‐3 months of age. B Kaplan–Meier survival curve of mice from (A) censoring for tumor appearance by μCT scanner. C, D Quantification of the number of adenomas (C) and carcinomas (D) per mouse at the time of death by histopathological analysis. E Follow‐up of tumor sizes by periodical μCT scanner, starting from the time point when the tumor was first detected. F, G (F) Kaplan–Meier curve indicating that lung tumors (including all tumors in the TMA, n = 105) displaying high expression of cytoplasmic SIRT1 (at least 20% of their neoplastic cells positive for SIRT1) show longer progression‐free survival time (*** P

    Journal: EMBO Reports

    Article Title: Sirt1 protects from K‐Ras‐driven lung carcinogenesis

    doi: 10.15252/embr.201643879

    Figure Lengend Snippet: Increased Sirt1 expression protects from non‐small cell lung carcinoma in mice and humans A Kaplan–Meier survival curve of mice of the indicated genotypes injected with 4‐OH tamoxifen at 2‐3 months of age. B Kaplan–Meier survival curve of mice from (A) censoring for tumor appearance by μCT scanner. C, D Quantification of the number of adenomas (C) and carcinomas (D) per mouse at the time of death by histopathological analysis. E Follow‐up of tumor sizes by periodical μCT scanner, starting from the time point when the tumor was first detected. F, G (F) Kaplan–Meier curve indicating that lung tumors (including all tumors in the TMA, n = 105) displaying high expression of cytoplasmic SIRT1 (at least 20% of their neoplastic cells positive for SIRT1) show longer progression‐free survival time (*** P

    Article Snippet: For the induction of Cre recombination in Figs and A, 2‐ to 3‐month‐old mice were subjected to a single i.p. injection of 1 mg of 4‐OH tamoxifen (Sigma) dissolved in corn oil.

    Techniques: Expressing, Mouse Assay, Injection

    Pneumocyte isolation and characterization A Strategy for pneumocyte isolation: dissociated lungs were analyzed by cytometry to discard aggregates (first panel); stained with DAPI to exclude dead cells (second panel); and further analyzed by size to discard debris (third panel). Finally, single, alive cells were analyzed for their expression of the lymphocytic marker CD45 or the endothelial marker CD31, and double negatives for CD31/CD45 were considered pneumocytes. B, C Representative immunohistochemistry stainings detecting Katushka‐positive cells after only 4 weeks of 4‐OH tamoxifen activation (B) or 4 weeks of 4‐OH tamoxifen pulse + 2 weeks with no tamoxifen treatment chase (C). Size bars represent 200 μm. Arrows indicate Katushka‐positive cells. D, E KEGG pathway clustering of differentially expressed genes between the K‐Ras‐KI; Sirt1‐WT and K‐Ras‐KI; Sirt1‐Tg pneumocytes isolated by FACS sorting in the pulse phase (D) or in the pulse + chase phase (E). Red columns represent cancer‐related pathways.

    Journal: EMBO Reports

    Article Title: Sirt1 protects from K‐Ras‐driven lung carcinogenesis

    doi: 10.15252/embr.201643879

    Figure Lengend Snippet: Pneumocyte isolation and characterization A Strategy for pneumocyte isolation: dissociated lungs were analyzed by cytometry to discard aggregates (first panel); stained with DAPI to exclude dead cells (second panel); and further analyzed by size to discard debris (third panel). Finally, single, alive cells were analyzed for their expression of the lymphocytic marker CD45 or the endothelial marker CD31, and double negatives for CD31/CD45 were considered pneumocytes. B, C Representative immunohistochemistry stainings detecting Katushka‐positive cells after only 4 weeks of 4‐OH tamoxifen activation (B) or 4 weeks of 4‐OH tamoxifen pulse + 2 weeks with no tamoxifen treatment chase (C). Size bars represent 200 μm. Arrows indicate Katushka‐positive cells. D, E KEGG pathway clustering of differentially expressed genes between the K‐Ras‐KI; Sirt1‐WT and K‐Ras‐KI; Sirt1‐Tg pneumocytes isolated by FACS sorting in the pulse phase (D) or in the pulse + chase phase (E). Red columns represent cancer‐related pathways.

    Article Snippet: For the induction of Cre recombination in Figs and A, 2‐ to 3‐month‐old mice were subjected to a single i.p. injection of 1 mg of 4‐OH tamoxifen (Sigma) dissolved in corn oil.

    Techniques: Isolation, Cytometry, Staining, Expressing, Marker, Immunohistochemistry, Activation Assay, FACS, Pulse Chase

    ADVIA Centaur® Vitamin D Total

    Journal: Clinical biochemistry

    Article Title: Performance Evaluation of Siemens ADVIA Centaur and Roche MODULAR Analytics E170 Total 25-OH Vitamin D Assays

    doi: 10.1016/j.clinbiochem.2012.06.002

    Figure Lengend Snippet: ADVIA Centaur® Vitamin D Total

    Article Snippet: The DiaSorin LIAISON 25 OH Vitamin D TOTAL assay is an automated direct competitive chemiluminescent immunoassay that detects 25-OH vitamins D2 and D3 and other hydroxylated metabolites in serum or plasma.

    Techniques:

    Linearity of the ADVIA Centaur and Modular E170 total Vitamin D assays.

    Journal: Clinical biochemistry

    Article Title: Performance Evaluation of Siemens ADVIA Centaur and Roche MODULAR Analytics E170 Total 25-OH Vitamin D Assays

    doi: 10.1016/j.clinbiochem.2012.06.002

    Figure Lengend Snippet: Linearity of the ADVIA Centaur and Modular E170 total Vitamin D assays.

    Article Snippet: The DiaSorin LIAISON 25 OH Vitamin D TOTAL assay is an automated direct competitive chemiluminescent immunoassay that detects 25-OH vitamins D2 and D3 and other hydroxylated metabolites in serum or plasma.

    Techniques:

    Inhibitory receptor blockers occluded the 8-OH-DPAT-induced excitation in Lmx1b f/f/p slice preparations. Hypoglossal burst frequency at baseline, during application of an inhibitory blocker mixture consisting of gabazine (0.5 μ m ), CGP 55845 (1

    Journal: The Journal of Neuroscience

    Article Title: Dual Effects of 5-HT1a Receptor Activation on Breathing in Neonatal Mice

    doi: 10.1523/JNEUROSCI.0864-13.2014

    Figure Lengend Snippet: Inhibitory receptor blockers occluded the 8-OH-DPAT-induced excitation in Lmx1b f/f/p slice preparations. Hypoglossal burst frequency at baseline, during application of an inhibitory blocker mixture consisting of gabazine (0.5 μ m ), CGP 55845 (1

    Article Snippet: To isolate the effect of 5-HT1a receptors, we coapplied 8-OH-DPAT (3 μ m ) with the 5-HT7 antagonist SB 269970 hydrochloride (Tocris Bioscience; 20 μ m , dissolved in aCSF) to rhythmogenic medullary slices ( n = 6 WT; n = 9 Lmx1bf/f/p ).

    Techniques:

    Traces of raw hypoglossal (XII) nerve activity in WT and Lmx1b f/f/p slices, before (baseline) and during (peak and steady-state) bath application of 8-OH-DPAT (100 μ m ). Represented are examples of a transient peak response (defined as the maximum

    Journal: The Journal of Neuroscience

    Article Title: Dual Effects of 5-HT1a Receptor Activation on Breathing in Neonatal Mice

    doi: 10.1523/JNEUROSCI.0864-13.2014

    Figure Lengend Snippet: Traces of raw hypoglossal (XII) nerve activity in WT and Lmx1b f/f/p slices, before (baseline) and during (peak and steady-state) bath application of 8-OH-DPAT (100 μ m ). Represented are examples of a transient peak response (defined as the maximum

    Article Snippet: To isolate the effect of 5-HT1a receptors, we coapplied 8-OH-DPAT (3 μ m ) with the 5-HT7 antagonist SB 269970 hydrochloride (Tocris Bioscience; 20 μ m , dissolved in aCSF) to rhythmogenic medullary slices ( n = 6 WT; n = 9 Lmx1bf/f/p ).

    Techniques: Activity Assay

    8-OH-DPAT differentially affected hypoglossal nerve discharge in WT and Lmx1b f/f/p rhythmogenic slices. A , Time course of burst frequency (relative to baseline) during a 10 min bath application of 8-OH-DPAT (100 μ m ) in WT and Lmx1b f/f/p slices.

    Journal: The Journal of Neuroscience

    Article Title: Dual Effects of 5-HT1a Receptor Activation on Breathing in Neonatal Mice

    doi: 10.1523/JNEUROSCI.0864-13.2014

    Figure Lengend Snippet: 8-OH-DPAT differentially affected hypoglossal nerve discharge in WT and Lmx1b f/f/p rhythmogenic slices. A , Time course of burst frequency (relative to baseline) during a 10 min bath application of 8-OH-DPAT (100 μ m ) in WT and Lmx1b f/f/p slices.

    Article Snippet: To isolate the effect of 5-HT1a receptors, we coapplied 8-OH-DPAT (3 μ m ) with the 5-HT7 antagonist SB 269970 hydrochloride (Tocris Bioscience; 20 μ m , dissolved in aCSF) to rhythmogenic medullary slices ( n = 6 WT; n = 9 Lmx1bf/f/p ).

    Techniques:

    Breathing was augmented in neonatal mouse pups lacking central 5-HT neurons after injection of 8-OH-DPAT. A , B , Breathing frequency ( A ) and breath amplitude ( B ; index of tidal volume) before and after injection of 8-OH-DPAT in WT and Lmx1b f/f/p pups (

    Journal: The Journal of Neuroscience

    Article Title: Dual Effects of 5-HT1a Receptor Activation on Breathing in Neonatal Mice

    doi: 10.1523/JNEUROSCI.0864-13.2014

    Figure Lengend Snippet: Breathing was augmented in neonatal mouse pups lacking central 5-HT neurons after injection of 8-OH-DPAT. A , B , Breathing frequency ( A ) and breath amplitude ( B ; index of tidal volume) before and after injection of 8-OH-DPAT in WT and Lmx1b f/f/p pups (

    Article Snippet: To isolate the effect of 5-HT1a receptors, we coapplied 8-OH-DPAT (3 μ m ) with the 5-HT7 antagonist SB 269970 hydrochloride (Tocris Bioscience; 20 μ m , dissolved in aCSF) to rhythmogenic medullary slices ( n = 6 WT; n = 9 Lmx1bf/f/p ).

    Techniques: Injection

    8-OH-DPAT elicited a transient increase in frequency (peak response) in Lmx1b f/f/p preparations, despite concurrent blockade of 5-HT 7 receptors. A , XII nerve and ∫XII nerve activity in an Lmx1b f/f/p slice during control conditions, bath application

    Journal: The Journal of Neuroscience

    Article Title: Dual Effects of 5-HT1a Receptor Activation on Breathing in Neonatal Mice

    doi: 10.1523/JNEUROSCI.0864-13.2014

    Figure Lengend Snippet: 8-OH-DPAT elicited a transient increase in frequency (peak response) in Lmx1b f/f/p preparations, despite concurrent blockade of 5-HT 7 receptors. A , XII nerve and ∫XII nerve activity in an Lmx1b f/f/p slice during control conditions, bath application

    Article Snippet: To isolate the effect of 5-HT1a receptors, we coapplied 8-OH-DPAT (3 μ m ) with the 5-HT7 antagonist SB 269970 hydrochloride (Tocris Bioscience; 20 μ m , dissolved in aCSF) to rhythmogenic medullary slices ( n = 6 WT; n = 9 Lmx1bf/f/p ).

    Techniques: Activity Assay

    Ventilatory traces from whole-body plethysmographic recordings in WT and Lmx1b f/f/p P2 mouse pups at baseline, 30 min, and 120 min after subcutaneous injection of 100 μg/kg 8-OH-DPAT.

    Journal: The Journal of Neuroscience

    Article Title: Dual Effects of 5-HT1a Receptor Activation on Breathing in Neonatal Mice

    doi: 10.1523/JNEUROSCI.0864-13.2014

    Figure Lengend Snippet: Ventilatory traces from whole-body plethysmographic recordings in WT and Lmx1b f/f/p P2 mouse pups at baseline, 30 min, and 120 min after subcutaneous injection of 100 μg/kg 8-OH-DPAT.

    Article Snippet: To isolate the effect of 5-HT1a receptors, we coapplied 8-OH-DPAT (3 μ m ) with the 5-HT7 antagonist SB 269970 hydrochloride (Tocris Bioscience; 20 μ m , dissolved in aCSF) to rhythmogenic medullary slices ( n = 6 WT; n = 9 Lmx1bf/f/p ).

    Techniques: Injection

    Associations between serum total 25‐ OH vitamin D quintile and mortality. Median 25‐ OH vitamin D is shown for each quintile. Demographic risk factors were age and sex. Clinical risk factors were body mass index, smoking status (current, prior vs never), renal disease, hypertension, hyperlipidemia, type 2 diabetes mellitus, family history of heart disease, prior myocardial infarction, congestive heart failure, whether ejection fraction was measured, ejection fraction (

    Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

    Article Title: Serum Total 25‐OH Vitamin D Adds Little Prognostic Value in Patients Undergoing Coronary Catheterization

    doi: 10.1161/JAHA.116.004289

    Figure Lengend Snippet: Associations between serum total 25‐ OH vitamin D quintile and mortality. Median 25‐ OH vitamin D is shown for each quintile. Demographic risk factors were age and sex. Clinical risk factors were body mass index, smoking status (current, prior vs never), renal disease, hypertension, hyperlipidemia, type 2 diabetes mellitus, family history of heart disease, prior myocardial infarction, congestive heart failure, whether ejection fraction was measured, ejection fraction (

    Article Snippet: Because 25‐OH vitamin D was measured by liquid chromatography–tandem mass spectrometry in Edmonton and by immunoassay (Liaison; DiaSorin) in Calgary, 240 identical samples were run by each method (R 2 =0.8, slope=1.0, intercept=−8), and Edmonton results were corrected to match those from Calgary by subtracting 8 nmol/L.

    Techniques:

    Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) Fmoc-Gly-OH, HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.

    Journal:

    Article Title: Synthesis and In Vitro Characterization of Novel Dextran-Methylprednisolone Conjugates with Peptide Linkers: Effects of Linker Length on Hydrolytic and Enzymatic Release of Methylprednisolone and its Peptidyl Intermediates

    doi: 10.1002/jps.21161

    Figure Lengend Snippet: Synthesis of MPS-mGGGGG-OH and MPS-mGGGGG-dextran. Reagents: (i) Piperidine (20%), DMF, (ii) Fmoc-Gly-OH, HBTU, DMF, (iii) Fmoc-mGly-OH, HBTU, DMF, (iv) MPS, HBTU.

    Article Snippet: Fmoc-Gly-Wang resin, coupling reagents, and Fmoc-amino acid building blocks, Fmoc-Gly-OH and Fmoc-methyl Gly (mGly)-OH, were purchased from Novabiochem (San Diego, CA).

    Techniques: