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Image Search Results
Journal: Oncology Letters
Article Title: LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance
doi: 10.3892/ol.2026.15456
Figure Lengend Snippet: LINC00473 knockdown efficiency in ovarian cancer cell lines. Quantitative analysis of LINC00473 expression in (A) SK-OV-3 and (B) A2780 cells after transfection with siLINC00473, compared with siNC and untreated controls. Data are presented as the mean±SD. ***P<0.001. LINC, long non-coding RNA; NC, negative control; si, small interfering RNA.
Article Snippet: SK-OV-3 and
Techniques: Knockdown, Expressing, Transfection, Negative Control, Small Interfering RNA
Journal: Oncology Letters
Article Title: LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance
doi: 10.3892/ol.2026.15456
Figure Lengend Snippet: Silencing LINC00473 significantly inhibits cell proliferation and induces apoptosis. Proliferation of (A) SK-OV-3 and (B) A2780 cells after transfection with siLINC00473, siNC and untreated controls (C). Proliferation inhibition rates of both cell lines post-transfection. Apoptosis status of (D) SK-OV-3 and (E) A2780 cells. Data are presented as the mean±SD. ***P<0.001. LINC, long non-coding RNA; NC, negative control; si, small interfering RNA.
Article Snippet: SK-OV-3 and
Techniques: Transfection, Inhibition, Negative Control, Small Interfering RNA
Journal: Oncology Letters
Article Title: LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance
doi: 10.3892/ol.2026.15456
Figure Lengend Snippet: Cellular protein expression after siLINC00473 transfection. (A) Differential expression patterns of five proteins in two ovarian cancer cell lines after transfection with siLINC00473 vs. the scrambled siNC. Semi-quantitative analysis of relative expression levels of (B) PARP, (C) caspase-3, (D) Sox2 and (E) YAP1 normalized to GAPDH, demonstrating significant downregulation in siLINC00473-treated cells compared with siNC. Data are presented as the mean±SD; ***P<0.001. LINC, long non-coding RNA; NC, negative control; PARP, poly (adenosine diphosphate-ribose) polymerase; si, small interfering RNA; YAP1, yes-associated protein 1.
Article Snippet: SK-OV-3 and
Techniques: Expressing, Transfection, Quantitative Proteomics, Negative Control, Small Interfering RNA
Journal: Oncology Letters
Article Title: LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance
doi: 10.3892/ol.2026.15456
Figure Lengend Snippet: Effect of siLINC00473 transfection on cellular sensitivity to CDDP. Comparison of cellular sensitivity to CDDP after transfection of (A) SK-OV-3 and (B) A2780 cells with siLINC00473, compared with the siNC group and the blank control group. ***P<0.001. LINC, long non-coding RNA; CDDP, cisplatin; NC, negative control; si, small interfering RNA.
Article Snippet: SK-OV-3 and
Techniques: Transfection, Comparison, Control, Negative Control, Small Interfering RNA