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antibody against s pneumoniae spp  (Novus Biologicals)
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Novus Biologicals antibody against s pneumoniae spp
Molecular detection of SARS-CoV-2 and Streptococcus <t>pneumoniae</t> in the lungs of a patient in Japan co-infected with both pathogens. The 42 lung sections were analyzed and the amount of SARS-CoV-2 RNA and S. pneumoniae DNA in each section was evaluated. A) The right lung was cut into 6 (R–I to R–VI); B) the left lung was cut into 7 (L–I to L–VII) coronal slices, from ventral to dorsal. Twenty-two right sections (R1–R22) in R–IV and R–V and 20 left sections (L1–L20) in L–V and L–IV are shown in black boxes. The dotted white line is the boundary between the upper and lower lobes. The SARS-CoV-2 RNA score is indicated by the number of red circles and the S. pneumoniae DNA score is indicated by the number of yellow circles. (-) indicates results under the detection limit. Scale bars indicate 2 cm. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
Antibody Against S Pneumoniae Spp, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/nb100-64502/pmc07920656-75-3-10?v=Novus+Biologicals
Average 92 stars, based on 1 article reviews
antibody against s pneumoniae spp - by Bioz Stars, 2026-07
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Molecular detection of SARS-CoV-2 and Streptococcus pneumoniae in the lungs of a patient in Japan co-infected with both pathogens. The 42 lung sections were analyzed and the amount of SARS-CoV-2 RNA and S. pneumoniae DNA in each section was evaluated. A) The right lung was cut into 6 (R–I to R–VI); B) the left lung was cut into 7 (L–I to L–VII) coronal slices, from ventral to dorsal. Twenty-two right sections (R1–R22) in R–IV and R–V and 20 left sections (L1–L20) in L–V and L–IV are shown in black boxes. The dotted white line is the boundary between the upper and lower lobes. The SARS-CoV-2 RNA score is indicated by the number of red circles and the S. pneumoniae DNA score is indicated by the number of yellow circles. (-) indicates results under the detection limit. Scale bars indicate 2 cm. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

Journal: Emerging Infectious Diseases

Article Title: Lung Pathology of Mutually Exclusive Co-infection with SARS-CoV-2 and Streptococcus pneumoniae

doi: 10.3201/eid2703.204024

Figure Lengend Snippet: Molecular detection of SARS-CoV-2 and Streptococcus pneumoniae in the lungs of a patient in Japan co-infected with both pathogens. The 42 lung sections were analyzed and the amount of SARS-CoV-2 RNA and S. pneumoniae DNA in each section was evaluated. A) The right lung was cut into 6 (R–I to R–VI); B) the left lung was cut into 7 (L–I to L–VII) coronal slices, from ventral to dorsal. Twenty-two right sections (R1–R22) in R–IV and R–V and 20 left sections (L1–L20) in L–V and L–IV are shown in black boxes. The dotted white line is the boundary between the upper and lower lobes. The SARS-CoV-2 RNA score is indicated by the number of red circles and the S. pneumoniae DNA score is indicated by the number of yellow circles. (-) indicates results under the detection limit. Scale bars indicate 2 cm. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

Article Snippet: IHC using an antibody against S. pneumoniae spp . (NB100–64502; Novus Biologicals, https://www.novusbio.com ) showed both intact streptococci and granular antigens staining in neutrophils, macrophages, or both, particularly in the lesion with bronchopneumonia ( , panel E).

Techniques: Infection

Microscopic findings of the lungs of a patient in Japan co-infected with SARS-CoV-2 and Streptococcus pneumoniae . A) Histopathology of lung section R12 (shown in ). Scale bar indicates 2 mm. B) Magnified image of the black square (top left) in panel A: exudative phase of diffuse alveolar damage (DAD) with hyaline membranes. Scale bar indicates 100 μm. C) Magnified image of the red square (bottom right) in panel A: edema and bronchopneumonia with massive infiltration of neutrophils in the alveolar spaces. Scale bar indicates 100 μm. D, E) Magnified images of the same areas of consecutive sections as B and C, respectively, showing SARS-CoV-2 antigen stained green (Vina green) and S. pneumoniae antigen stained brown (3,3′-diaminobenzidine) by enzyme-labeled double immunohistochemistry. The SARS-CoV-2 antigens were detected predominantly in the DAD area (D; scale bar indicates 50 μm). The S. pneumoniae antigens were detected predominantly in the bronchopneumonia area (E; scale bar indicates 50 μm). Insets show magnified images of the staining cells (scale bars indicate 10 μm).

Journal: Emerging Infectious Diseases

Article Title: Lung Pathology of Mutually Exclusive Co-infection with SARS-CoV-2 and Streptococcus pneumoniae

doi: 10.3201/eid2703.204024

Figure Lengend Snippet: Microscopic findings of the lungs of a patient in Japan co-infected with SARS-CoV-2 and Streptococcus pneumoniae . A) Histopathology of lung section R12 (shown in ). Scale bar indicates 2 mm. B) Magnified image of the black square (top left) in panel A: exudative phase of diffuse alveolar damage (DAD) with hyaline membranes. Scale bar indicates 100 μm. C) Magnified image of the red square (bottom right) in panel A: edema and bronchopneumonia with massive infiltration of neutrophils in the alveolar spaces. Scale bar indicates 100 μm. D, E) Magnified images of the same areas of consecutive sections as B and C, respectively, showing SARS-CoV-2 antigen stained green (Vina green) and S. pneumoniae antigen stained brown (3,3′-diaminobenzidine) by enzyme-labeled double immunohistochemistry. The SARS-CoV-2 antigens were detected predominantly in the DAD area (D; scale bar indicates 50 μm). The S. pneumoniae antigens were detected predominantly in the bronchopneumonia area (E; scale bar indicates 50 μm). Insets show magnified images of the staining cells (scale bars indicate 10 μm).

Article Snippet: IHC using an antibody against S. pneumoniae spp . (NB100–64502; Novus Biologicals, https://www.novusbio.com ) showed both intact streptococci and granular antigens staining in neutrophils, macrophages, or both, particularly in the lesion with bronchopneumonia ( , panel E).

Techniques: Infection, Histopathology, Staining, Labeling, Immunohistochemistry

Quantification of SARS-CoV-2 RNA and Streptococcus pneumoniae DNA in 42 lung sections from a patient in Japan co-infected with both pathogens*

Journal: Emerging Infectious Diseases

Article Title: Lung Pathology of Mutually Exclusive Co-infection with SARS-CoV-2 and Streptococcus pneumoniae

doi: 10.3201/eid2703.204024

Figure Lengend Snippet: Quantification of SARS-CoV-2 RNA and Streptococcus pneumoniae DNA in 42 lung sections from a patient in Japan co-infected with both pathogens*

Article Snippet: IHC using an antibody against S. pneumoniae spp . (NB100–64502; Novus Biologicals, https://www.novusbio.com ) showed both intact streptococci and granular antigens staining in neutrophils, macrophages, or both, particularly in the lesion with bronchopneumonia ( , panel E).

Techniques: