Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: Synthetic scheme of mPEG-PLGA-PPA copolymer. PEG: poly(ethylene glycol); PLGA: poly( l -glutamic acid); PPA: poly( l -phenylalanine).

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques:

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: 1 H NMR of mPEG-poly(BLG)-PPA ( A ) and mPEG-PLGA-PPA ( B ) in DMSO-d 6.

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques:

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: FT-IR spectra of copolymer mPEG-PLGA-PPA (a) and mPEG-poly(BLG)-PPA (b).

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques:

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: Molecular weight of mPEG-PLGA-PPA copolymers.

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques: Molecular Weight

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: Critical micelle concentration (CMC) values of mPEG-PLGA-PPA copolymers.

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques: Concentration Assay

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: SEM micrographs of ( a ) mPEG 44 -PLGA 9 -PPA 14 showing maze pattern, ( b ) mPEG 44 -PLGA 9 -PPA 14 , ( c ) mPEG 44 -PLGA 20 -PPA 18 showing dendritic pattern and ( d ) mPEG 44 -PLGA 20 -PPA 18 .

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques:

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: Circular dichroism spectra of mPEG-PLGA-PPA micelles at different pH.

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques:

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: Secondary conformation of polymer micelles at different pH.

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques:

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: Drug loading profiles of mPEG-PLGA-PPA copolymers with different block ratios.

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques: Blocking Assay

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: Drug loading content (DLC) and drug loading efficiency (DLE) of Sorafenib (SFN)-loaded assembled micelles of different drug/carrier mass ratio.

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques:

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: In vitro drug release profiles of SFN loaded mPEG-PLGA-PPA micelles at pH 7.4.

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques: In Vitro

Journal: Pharmaceutics

Article Title: Polypeptides Micelles Composed of Methoxy-Poly(Ethylene Glycol)-Poly( l -Glutamic Acid)-Poly( l -Phenylalanine) Triblock Polymer for Sustained Drug Delivery

doi: 10.3390/pharmaceutics10040230

Figure Lengend Snippet: In vitro drug release profiles of SFN loaded mPEG-PLGA-PAA micelles.

Article Snippet: The critical micelle concentrations (CMC) of synthesized mPEG-PLGA-PPA was recorded on an Aminco Bowman Series 2 Luminescence Spectrometer (Spectrolab, Inc., Sylmar, CA, USA) by the fluorescence technique with a pyrene probe.

Techniques: In Vitro