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Osmotic Minipumps, supplied by Durect Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Osmotic Minipump, supplied by Durect Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Osmotic Mini Pumps, supplied by ALZA Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Durect Corporation minipump
Minipump, supplied by Durect Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Durect Corporation 1002 minipumps
(A) Effect of leptin treatment on hyperglycemia induced by gene recombination in Ai-IRKO and Ai-DKO compared to Controls (n = 5–7 per group). Leptin (10 mg/day) was administered using Alzet <t>1002</t> <t>minipumps</t> between day −3 and day 9 surrounding tamoxifen-treatment. (B) Fasted serum insulin concentrations at day 3 after tamoxifen-treatment with or without leptin (n = 5–7 per group). (C) Liver sections stained with Oil Red O for Control, Ai-IRKO and Ai-DKO with saline or leptin at day 3. Scale bars, 100 μm. (D) Weights of SC and BAT fat at day 9 in Ai-IRKO (Saline: n=6, leptin: n=5), Ai-DKO (Saline: n = 7, leptin: n = 6) and Control (Saline: n = 9, leptin: n = 7). (E) Immunofluorescence staining for GFP (green), Td-tomato (red) and DAPI (blue) in SC-WAT and BAT from Control mTmG and Ai-DKO mTmG, as indicated, at day 30. Scale bars, 50 μm. (F) Perilipin (green) staining of SC and BAT in Ai-DKO (with saline or leptin) at day 9 and 30. Scale bars, 50 μm. (G) Tissue weights of SC and BAT at day 30 in Ai-DKO (Saline: n = 9, leptin: n = 5) and Control (Saline: n = 9, leptin: n = 5). Statistical significance is as in Figure 2.
1002 Minipumps, supplied by Durect Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Durect Corporation minipump + microcannula set
(A) Effect of leptin treatment on hyperglycemia induced by gene recombination in Ai-IRKO and Ai-DKO compared to Controls (n = 5–7 per group). Leptin (10 mg/day) was administered using Alzet <t>1002</t> <t>minipumps</t> between day −3 and day 9 surrounding tamoxifen-treatment. (B) Fasted serum insulin concentrations at day 3 after tamoxifen-treatment with or without leptin (n = 5–7 per group). (C) Liver sections stained with Oil Red O for Control, Ai-IRKO and Ai-DKO with saline or leptin at day 3. Scale bars, 100 μm. (D) Weights of SC and BAT fat at day 9 in Ai-IRKO (Saline: n=6, leptin: n=5), Ai-DKO (Saline: n = 7, leptin: n = 6) and Control (Saline: n = 9, leptin: n = 7). (E) Immunofluorescence staining for GFP (green), Td-tomato (red) and DAPI (blue) in SC-WAT and BAT from Control mTmG and Ai-DKO mTmG, as indicated, at day 30. Scale bars, 50 μm. (F) Perilipin (green) staining of SC and BAT in Ai-DKO (with saline or leptin) at day 9 and 30. Scale bars, 50 μm. (G) Tissue weights of SC and BAT at day 30 in Ai-DKO (Saline: n = 9, leptin: n = 5) and Control (Saline: n = 9, leptin: n = 5). Statistical significance is as in Figure 2.
Minipump + Microcannula Set, supplied by Durect Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Dawley Inc osmotic minipump delivering methadone
(A) Effect of leptin treatment on hyperglycemia induced by gene recombination in Ai-IRKO and Ai-DKO compared to Controls (n = 5–7 per group). Leptin (10 mg/day) was administered using Alzet <t>1002</t> <t>minipumps</t> between day −3 and day 9 surrounding tamoxifen-treatment. (B) Fasted serum insulin concentrations at day 3 after tamoxifen-treatment with or without leptin (n = 5–7 per group). (C) Liver sections stained with Oil Red O for Control, Ai-IRKO and Ai-DKO with saline or leptin at day 3. Scale bars, 100 μm. (D) Weights of SC and BAT fat at day 9 in Ai-IRKO (Saline: n=6, leptin: n=5), Ai-DKO (Saline: n = 7, leptin: n = 6) and Control (Saline: n = 9, leptin: n = 7). (E) Immunofluorescence staining for GFP (green), Td-tomato (red) and DAPI (blue) in SC-WAT and BAT from Control mTmG and Ai-DKO mTmG, as indicated, at day 30. Scale bars, 50 μm. (F) Perilipin (green) staining of SC and BAT in Ai-DKO (with saline or leptin) at day 9 and 30. Scale bars, 50 μm. (G) Tissue weights of SC and BAT at day 30 in Ai-DKO (Saline: n = 9, leptin: n = 5) and Control (Saline: n = 9, leptin: n = 5). Statistical significance is as in Figure 2.
Osmotic Minipump Delivering Methadone, supplied by Dawley Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Durect Corporation osmotic minipumps 2 week
(A) Effect of leptin treatment on hyperglycemia induced by gene recombination in Ai-IRKO and Ai-DKO compared to Controls (n = 5–7 per group). Leptin (10 mg/day) was administered using Alzet <t>1002</t> <t>minipumps</t> between day −3 and day 9 surrounding tamoxifen-treatment. (B) Fasted serum insulin concentrations at day 3 after tamoxifen-treatment with or without leptin (n = 5–7 per group). (C) Liver sections stained with Oil Red O for Control, Ai-IRKO and Ai-DKO with saline or leptin at day 3. Scale bars, 100 μm. (D) Weights of SC and BAT fat at day 9 in Ai-IRKO (Saline: n=6, leptin: n=5), Ai-DKO (Saline: n = 7, leptin: n = 6) and Control (Saline: n = 9, leptin: n = 7). (E) Immunofluorescence staining for GFP (green), Td-tomato (red) and DAPI (blue) in SC-WAT and BAT from Control mTmG and Ai-DKO mTmG, as indicated, at day 30. Scale bars, 50 μm. (F) Perilipin (green) staining of SC and BAT in Ai-DKO (with saline or leptin) at day 9 and 30. Scale bars, 50 μm. (G) Tissue weights of SC and BAT at day 30 in Ai-DKO (Saline: n = 9, leptin: n = 5) and Control (Saline: n = 9, leptin: n = 5). Statistical significance is as in Figure 2.
Osmotic Minipumps 2 Week, supplied by Durect Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sibata Scientific portable pump mp-∑ 30
(A) Effect of leptin treatment on hyperglycemia induced by gene recombination in Ai-IRKO and Ai-DKO compared to Controls (n = 5–7 per group). Leptin (10 mg/day) was administered using Alzet <t>1002</t> <t>minipumps</t> between day −3 and day 9 surrounding tamoxifen-treatment. (B) Fasted serum insulin concentrations at day 3 after tamoxifen-treatment with or without leptin (n = 5–7 per group). (C) Liver sections stained with Oil Red O for Control, Ai-IRKO and Ai-DKO with saline or leptin at day 3. Scale bars, 100 μm. (D) Weights of SC and BAT fat at day 9 in Ai-IRKO (Saline: n=6, leptin: n=5), Ai-DKO (Saline: n = 7, leptin: n = 6) and Control (Saline: n = 9, leptin: n = 7). (E) Immunofluorescence staining for GFP (green), Td-tomato (red) and DAPI (blue) in SC-WAT and BAT from Control mTmG and Ai-DKO mTmG, as indicated, at day 30. Scale bars, 50 μm. (F) Perilipin (green) staining of SC and BAT in Ai-DKO (with saline or leptin) at day 9 and 30. Scale bars, 50 μm. (G) Tissue weights of SC and BAT at day 30 in Ai-DKO (Saline: n = 9, leptin: n = 5) and Control (Saline: n = 9, leptin: n = 5). Statistical significance is as in Figure 2.
Portable Pump Mp ∑ 30, supplied by Sibata Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sibata Scientific minipump mp-σ100hn
(A) Effect of leptin treatment on hyperglycemia induced by gene recombination in Ai-IRKO and Ai-DKO compared to Controls (n = 5–7 per group). Leptin (10 mg/day) was administered using Alzet <t>1002</t> <t>minipumps</t> between day −3 and day 9 surrounding tamoxifen-treatment. (B) Fasted serum insulin concentrations at day 3 after tamoxifen-treatment with or without leptin (n = 5–7 per group). (C) Liver sections stained with Oil Red O for Control, Ai-IRKO and Ai-DKO with saline or leptin at day 3. Scale bars, 100 μm. (D) Weights of SC and BAT fat at day 9 in Ai-IRKO (Saline: n=6, leptin: n=5), Ai-DKO (Saline: n = 7, leptin: n = 6) and Control (Saline: n = 9, leptin: n = 7). (E) Immunofluorescence staining for GFP (green), Td-tomato (red) and DAPI (blue) in SC-WAT and BAT from Control mTmG and Ai-DKO mTmG, as indicated, at day 30. Scale bars, 50 μm. (F) Perilipin (green) staining of SC and BAT in Ai-DKO (with saline or leptin) at day 9 and 30. Scale bars, 50 μm. (G) Tissue weights of SC and BAT at day 30 in Ai-DKO (Saline: n = 9, leptin: n = 5) and Control (Saline: n = 9, leptin: n = 5). Statistical significance is as in Figure 2.
Minipump Mp σ100hn, supplied by Sibata Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


(A) Effect of leptin treatment on hyperglycemia induced by gene recombination in Ai-IRKO and Ai-DKO compared to Controls (n = 5–7 per group). Leptin (10 mg/day) was administered using Alzet 1002 minipumps between day −3 and day 9 surrounding tamoxifen-treatment. (B) Fasted serum insulin concentrations at day 3 after tamoxifen-treatment with or without leptin (n = 5–7 per group). (C) Liver sections stained with Oil Red O for Control, Ai-IRKO and Ai-DKO with saline or leptin at day 3. Scale bars, 100 μm. (D) Weights of SC and BAT fat at day 9 in Ai-IRKO (Saline: n=6, leptin: n=5), Ai-DKO (Saline: n = 7, leptin: n = 6) and Control (Saline: n = 9, leptin: n = 7). (E) Immunofluorescence staining for GFP (green), Td-tomato (red) and DAPI (blue) in SC-WAT and BAT from Control mTmG and Ai-DKO mTmG, as indicated, at day 30. Scale bars, 50 μm. (F) Perilipin (green) staining of SC and BAT in Ai-DKO (with saline or leptin) at day 9 and 30. Scale bars, 50 μm. (G) Tissue weights of SC and BAT at day 30 in Ai-DKO (Saline: n = 9, leptin: n = 5) and Control (Saline: n = 9, leptin: n = 5). Statistical significance is as in Figure 2.

Journal: Cell metabolism

Article Title: Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor

doi: 10.1016/j.cmet.2016.12.008

Figure Lengend Snippet: (A) Effect of leptin treatment on hyperglycemia induced by gene recombination in Ai-IRKO and Ai-DKO compared to Controls (n = 5–7 per group). Leptin (10 mg/day) was administered using Alzet 1002 minipumps between day −3 and day 9 surrounding tamoxifen-treatment. (B) Fasted serum insulin concentrations at day 3 after tamoxifen-treatment with or without leptin (n = 5–7 per group). (C) Liver sections stained with Oil Red O for Control, Ai-IRKO and Ai-DKO with saline or leptin at day 3. Scale bars, 100 μm. (D) Weights of SC and BAT fat at day 9 in Ai-IRKO (Saline: n=6, leptin: n=5), Ai-DKO (Saline: n = 7, leptin: n = 6) and Control (Saline: n = 9, leptin: n = 7). (E) Immunofluorescence staining for GFP (green), Td-tomato (red) and DAPI (blue) in SC-WAT and BAT from Control mTmG and Ai-DKO mTmG, as indicated, at day 30. Scale bars, 50 μm. (F) Perilipin (green) staining of SC and BAT in Ai-DKO (with saline or leptin) at day 9 and 30. Scale bars, 50 μm. (G) Tissue weights of SC and BAT at day 30 in Ai-DKO (Saline: n = 9, leptin: n = 5) and Control (Saline: n = 9, leptin: n = 5). Statistical significance is as in Figure 2.

Article Snippet: Leptin (10 mg/day) was administered using Alzet 1002 minipumps between day −3 and day 9 surrounding tamoxifen-treatment. (B) Fasted serum insulin concentrations at day 3 after tamoxifen-treatment with or without leptin ( n = 5–7 per group). ( C ) Liver sections stained with Oil Red O for Control, Ai-IRKO and Ai-DKO with saline or leptin at day 3.

Techniques: Staining, Immunofluorescence