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MicroFluidic Systems
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SynVivo Inc
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Image Search Results
Journal: Fluids and Barriers of the CNS
Article Title: Permeability across a novel microfluidic blood-tumor barrier model
doi: 10.1186/s12987-017-0050-9
Figure Lengend Snippet: a Schematic of SynVivo BBB microfluidic chip: ( 1 ) inlet port where media with or without tracer is flowed through the outer compartment to change media for HUVECs. ( 2 ) Outer compartment, containing HUVECs. ( 3 ) 3 μm pores, to allow diffusion of media and tracer between the central and outer compartments. ( 4 ) Central compartment, containing astrocytes or cancer cells. ( 5 ) Outlet port where perfusate from the outer compartment is collected. ( 6 ) Inlet port for central compartment, used to seed and change media for the astrocytes/cancer cells in the central compartment. ( 7 ) Output ports where perfusate from the central compartment is collected. b Morphology of astrocytes in the central compartment and HUVECs in the outer compartment without the addition of flow ( c ) morphology of astrocytes in the central compartment and HUVECs in the outer compartment with the addition of flow. d Representation of where the regions of interest (ROI) measurements are taken for data analysis. White rectangle scale bars 500 μm
Article Snippet: Fig. 1 a Schematic of
Techniques: Diffusion-based Assay
Journal: Fluids and Barriers of the CNS
Article Title: Permeability across a novel microfluidic blood-tumor barrier model
doi: 10.1186/s12987-017-0050-9
Figure Lengend Snippet: The diffusion rates of free MW tracers <1000 Da, 3–5 kDa and >60 kDa in an unrestricted, cell free microfluidic chips are shown. Statistical significance was determined using one-way ANOVA followed by Tukey’s multiple comparison tests, and student’s t test; n = 3–6 chips. All data represent mean ± SEM
Article Snippet: Fig. 1 a Schematic of
Techniques: Diffusion-based Assay