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Image Search Results
Journal: BMC Bioinformatics
Article Title: Impact of the spotted microarray preprocessing method on fold-change compression and variance stability
doi: 10.1186/1471-2105-12-413
Figure Lengend Snippet: Correlation between Microarray and Taqman fold-changes
Article Snippet: As our study focuses on the preprocessing of spotted microarray data, we decided to perform analyses on a high density spotted oligonucleotide microarray platform (CodeLink Human Whole Genome from GE Healthcare) as well as on a low
Techniques: Microarray
Journal: BMC Bioinformatics
Article Title: Impact of the spotted microarray preprocessing method on fold-change compression and variance stability
doi: 10.1186/1471-2105-12-413
Figure Lengend Snippet: Scatter plot between microarray and Taqman . Scatter plot of log2 fold-changes obtained from quantitative PCR versus the log2 fold-changes obtained from microarray after the best- (Standard background correction with log2 transformation) and the worst- (No background correction with glog transformation) preprocessing methods. Microarray data leads to fold-change compressions for many genes, especially with the No background correction and the glog transformation (see Figure2).
Article Snippet: As our study focuses on the preprocessing of spotted microarray data, we decided to perform analyses on a high density spotted oligonucleotide microarray platform (CodeLink Human Whole Genome from GE Healthcare) as well as on a low
Techniques: Microarray, Real-time Polymerase Chain Reaction, Transformation Assay
Journal: BMC Bioinformatics
Article Title: Impact of the spotted microarray preprocessing method on fold-change compression and variance stability
doi: 10.1186/1471-2105-12-413
Figure Lengend Snippet: GE Healthcare Fold-change compression . Lowess curves of the log2 fold-change compression estimated with the GE Healtchare platform as a function of the average processed intensity. The No background correction as well as the glog transformation produce high fold-change compression at low processed intensities. The fold-change compression at low intensities affects the correlation between gold-standard fold-changes and those obtained with microarray data (see Table 2).
Article Snippet: As our study focuses on the preprocessing of spotted microarray data, we decided to perform analyses on a high density spotted oligonucleotide microarray platform (CodeLink Human Whole Genome from GE Healthcare) as well as on a low
Techniques: Transformation Assay, Microarray
Journal: Frontiers in Pharmacology
Article Title: Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin—Two Main Metabolites of Curcuma longa —in Cancer Cells
doi: 10.3389/fphar.2017.00038
Figure Lengend Snippet: Dendrograms and cluster image map of curcumin obtained by hierarchical cluster analysis of mRNA expression of 40 genes in the NCI cell line panel as analyzed by the Novartis microarray platform . The dendrogram on the left shows the clustering of cell lines and the dendrogram on the top shows the clustering of genes. The cluster image map shows each single mRNA expression value obtained by microarray analysis. The expression values have been normalized and color-coded.
Article Snippet: In the present investigation, we focused only on the
Techniques: Expressing, Microarray
Journal: Frontiers in Pharmacology
Article Title: Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin—Two Main Metabolites of Curcuma longa —in Cancer Cells
doi: 10.3389/fphar.2017.00038
Figure Lengend Snippet: Dendrograms and cluster image map of vitamin C obtained by hierarchical cluster analysis of mRNA expression of 40 genes in the NCI cell line panel as analyzed by the Novartis microarray platform . The dendrogram on the left shows the clustering of cell lines and the dendrogram on the top shows the clustering of genes. The cluster image map shows each single mRNA expression value obtained by microarray analysis. The expression values have been normalized and color-coded.
Article Snippet: In the present investigation, we focused only on the
Techniques: Expressing, Microarray