mgcd265 Search Results


93
MedChemExpress glesatinib
Glesatinib, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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93/100 stars
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93
TargetMol mgcd 265 analog
Mgcd 265 Analog, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
mgcd 265 analog - by Bioz Stars, 2026-05
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93
Selleck Chemicals 657 24 9 mgcd 265 selleck s1361
657 24 9 Mgcd 265 Selleck S1361, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
657 24 9 mgcd 265 selleck s1361 - by Bioz Stars, 2026-05
93/100 stars
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90
MethylGene Inc mgcd265
Mgcd265, supplied by MethylGene Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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90
Mirati Therapeutics glesatinib mgcd265
Type II kinase inhibitors against Axl.
Glesatinib Mgcd265, supplied by Mirati Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
glesatinib mgcd265 - by Bioz Stars, 2026-05
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90
MultiTarget Pharmaceuticals mgcd265
POG analyses in all five adenoid cystic carcinoma cases yielded informative and actionable results
Mgcd265, supplied by MultiTarget Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
mgcd265 - by Bioz Stars, 2026-05
90/100 stars
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90
Cayman Chemical mgcd-265 20097
POG analyses in all five adenoid cystic carcinoma cases yielded informative and actionable results
Mgcd 265 20097, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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N/A
InformationMGCD-265 is a potent, multi-target and ATP-competitive inhibitor ofc-MetandVEGFR1/2/3withIC50of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.In vitroMGCD-265 is a multi-target inhibitor of receptor tyrosine kinases. MGCD-265 potently inhibits
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N/A
MGCD-265 analog is a potent and oral bioavailable inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50 s of 29 nM and 10 nM, respectively. MGCD-265 analog has significant antitumor activity.
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N/A
MGCD-265 is a potent, multi-target, and ATP-competitive receptor tyrosine kinase inhibitor of Met, Flt-1, Flt-4, Flk-1, Ron, and Tie-2 (IC50 = 1 nM - 7 nM).
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N/A
Application:MGCD-265 analog is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50s of 29 nM and 10 nM, respectively. MGCD-265 analog has significant antitumor activity
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N/A
MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively and also inhibits Ron and Tie2.
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Image Search Results


Type II kinase inhibitors against Axl.

Journal: International Journal of Molecular Sciences

Article Title: Therapeutic Targeting of the Gas6/Axl Signaling Pathway in Cancer

doi: 10.3390/ijms22189953

Figure Lengend Snippet: Type II kinase inhibitors against Axl.

Article Snippet: Glesatinib (MGCD265) Mirati Therapeutics , c-Met , RON, Axl, VEGFR , Ν/A , NCT02954991 , II , Combination , Active, not recruiting , NSCLC.

Techniques: In Vitro

POG analyses in all five adenoid cystic carcinoma cases yielded informative and actionable results

Journal: Cold Spring Harbor Molecular Case Studies

Article Title: Personalized oncogenomic analysis of metastatic adenoid cystic carcinoma: using whole-genome sequencing to inform clinical decision-making

doi: 10.1101/mcs.a002626

Figure Lengend Snippet: POG analyses in all five adenoid cystic carcinoma cases yielded informative and actionable results

Article Snippet: Patient 3 exhibited aberrations in MET expression and was subsequently enrolled in a phase I clinical trial with MGCD265, a multitarget and ATP-competitive inhibitor of c-MET and VEGFR1/2/3 that has recently been studied in lung cancer models ( ).

Techniques: Biomarker Discovery, Over Expression