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Tocris
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SmithKline Corporation
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Verlag GmbH
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Ayerst Laboratories
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Cayman Chemical
sb242084 6-chloro-5-methyl-1[[2-(2-methylpyrid-3-yloxy)pyrid-5-yl]carbamoyl]indoline dihydrochloride ![]() Sb242084 6 Chloro 5 Methyl 1[[2 (2 Methylpyrid 3 Yloxy)pyrid 5 Yl]Carbamoyl]Indoline Dihydrochloride, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/product/methylpyruvate/pmc10853020-681-0-3?v=Cayman+Chemical Average 90 stars, based on 1 article reviews
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Neurolixis
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NEOCHEMA GmbH
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Image Search Results
Journal: Journal of medicinal chemistry
Article Title: Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT 2C Receptor and Dual 5-HT 2C /5-HT 2A Receptor Modulators
doi: 10.1021/acs.jmedchem.3c00908
Figure Lengend Snippet: Impact of compound 13 on novelty-induced locomotor activity in Sprague–Dawley rats. (A) Male rats (n = 12/treatment) naïve to the activity monitors were injected with vehicle (ip) or compound 13 (3, 10, or 30 mg/kg, ip) 30 min prior to the start of the 90 min locomotor assessment. The mean total ambulations (±SEM) for the 90 min session are plotted with open circles representing individual rats (*p < 0.05 vs Veh). (B) In a separate cohort (n = 11–12/treatment), Veh, the 5-HT2CR antagonist SB242084 (0.5 mg/kg, ip), or the 5-HT2AR antagonist M100907 (0.1 mg/kg, ip) plus Veh or 13 (30 mg/kg) was administered 30 min prior to the 90 min locomotor assessment. Average activity (mean ± SEM) is shown for each treatment group and compared to animals receiving Veh + Cmpd 13 (*p < 0.05). The average basal activity (Veh + Veh; dashed line) is shown for reference. Please see Experimental Section for Veh descriptions.
Article Snippet:
Techniques: Activity Assay, Injection