mel-2 Search Results


sk mel 2  (ATCC)
97
ATCC sk mel 2
Sk Mel 2, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/pm41839860-34-32-42?v=ATCC
Average 97 stars, based on 1 article reviews
sk mel 2 - by Bioz Stars, 2026-08
97/100 stars
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human melanoma cells  (ATCC)
95
ATCC human melanoma cells
Human Melanoma Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/us12569496-314-1-7?v=ATCC
Average 95 stars, based on 1 article reviews
human melanoma cells - by Bioz Stars, 2026-08
95/100 stars
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human melanoma sk mel 2 cells  (CLS Cell Lines Service GmbH)
91
CLS Cell Lines Service GmbH human melanoma sk mel 2 cells
Human Melanoma Sk Mel 2 Cells, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/pmc09369069-183-24-28?v=CLS+Cell+Lines+Service+GmbH
Average 91 stars, based on 1 article reviews
human melanoma sk mel 2 cells - by Bioz Stars, 2026-08
91/100 stars
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melanoma mug mel2  (DSMZ)
92
DSMZ melanoma mug mel2
Melanoma Mug Mel2, supplied by DSMZ, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/pmc08072566-120-0-2?v=DSMZ
Average 92 stars, based on 1 article reviews
melanoma mug mel2 - by Bioz Stars, 2026-08
92/100 stars
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solid-phase extraction radioimmunoassay reagents rk-mel2  (BUHLMANN Laboratories)
90
BUHLMANN Laboratories solid-phase extraction radioimmunoassay reagents rk-mel2
Solid Phase Extraction Radioimmunoassay Reagents Rk Mel2, supplied by BUHLMANN Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/10__1113_slash_jp277186-88-14-14?v=BUHLMANN+Laboratories
Average 90 stars, based on 1 article reviews
solid-phase extraction radioimmunoassay reagents rk-mel2 - by Bioz Stars, 2026-08
90/100 stars
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mel2 framework  (AgResearch)
90
AgResearch mel2 framework
Mel2 Framework, supplied by AgResearch, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/10__1177_slash_1035719x18823567-28-1-10?v=AgResearch
Average 90 stars, based on 1 article reviews
mel2 framework - by Bioz Stars, 2026-08
90/100 stars
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human embryonic stem (es) cells line mel-2  (Merck KGaA)
90
Merck KGaA human embryonic stem (es) cells line mel-2
Human Embryonic Stem (Es) Cells Line Mel 2, supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/pmc05104983-181-0-7?v=Merck+KGaA
Average 90 stars, based on 1 article reviews
human embryonic stem (es) cells line mel-2 - by Bioz Stars, 2026-08
90/100 stars
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sk-mel-2 cells  (AstraZeneca ltd)
90
AstraZeneca ltd sk-mel-2 cells
a) Violin plot showing proximal to distal usage shifts across each class of significant APA event. Proximal to distal usage shift is calculated as: dPA change in usage - pPA change in usage. White square = median. b) Scatter plots displaying Pearson correlation (r) of DMAi-induced poly(A) site usage change between different cell lines. Upper left = LU-99 vs MCF7, Lower left = NCI-H838 vs SUM149PT, Upper right = <t>PANC0403</t> vs GP2D. Lower right = HCT116 p53 +/+ vs U2OS. c) Distribution of proximal poly(A) usage across all genes in a patient-derived lung tumour organoid model versus normal lung tissue organoids derived from the same patient. Scale: 0 = 0% usage, 1 = 100% usage. Statistical significance was calculated using the Kruskal-Wallis Test. d) An example of a 3’ UTR ( Prkca) whose shortening upon T cell activation (blue) is prevented by DMAi (red).
Sk Mel 2 Cells, supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/bio_rxiv__2025__03__06__641848-167-3-13?v=AstraZeneca+ltd
Average 90 stars, based on 1 article reviews
sk-mel-2 cells - by Bioz Stars, 2026-08
90/100 stars
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sk-mel-2  (LGC Promochem)
90
LGC Promochem sk-mel-2
a) Violin plot showing proximal to distal usage shifts across each class of significant APA event. Proximal to distal usage shift is calculated as: dPA change in usage - pPA change in usage. White square = median. b) Scatter plots displaying Pearson correlation (r) of DMAi-induced poly(A) site usage change between different cell lines. Upper left = LU-99 vs MCF7, Lower left = NCI-H838 vs SUM149PT, Upper right = <t>PANC0403</t> vs GP2D. Lower right = HCT116 p53 +/+ vs U2OS. c) Distribution of proximal poly(A) usage across all genes in a patient-derived lung tumour organoid model versus normal lung tissue organoids derived from the same patient. Scale: 0 = 0% usage, 1 = 100% usage. Statistical significance was calculated using the Kruskal-Wallis Test. d) An example of a 3’ UTR ( Prkca) whose shortening upon T cell activation (blue) is prevented by DMAi (red).
Sk Mel 2, supplied by LGC Promochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/10__1074_slash_jbc__m800271200-54-0-7?v=LGC+Promochem
Average 90 stars, based on 1 article reviews
sk-mel-2 - by Bioz Stars, 2026-08
90/100 stars
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d.mel-2 cells expressing the mcherry-sas6 centrosomal marker protein under the control of mt promoter in glass bottom dishes  (MatTek)
90
MatTek d.mel-2 cells expressing the mcherry-sas6 centrosomal marker protein under the control of mt promoter in glass bottom dishes
a) Violin plot showing proximal to distal usage shifts across each class of significant APA event. Proximal to distal usage shift is calculated as: dPA change in usage - pPA change in usage. White square = median. b) Scatter plots displaying Pearson correlation (r) of DMAi-induced poly(A) site usage change between different cell lines. Upper left = LU-99 vs MCF7, Lower left = NCI-H838 vs SUM149PT, Upper right = <t>PANC0403</t> vs GP2D. Lower right = HCT116 p53 +/+ vs U2OS. c) Distribution of proximal poly(A) usage across all genes in a patient-derived lung tumour organoid model versus normal lung tissue organoids derived from the same patient. Scale: 0 = 0% usage, 1 = 100% usage. Statistical significance was calculated using the Kruskal-Wallis Test. d) An example of a 3’ UTR ( Prkca) whose shortening upon T cell activation (blue) is prevented by DMAi (red).
D.Mel 2 Cells Expressing The Mcherry Sas6 Centrosomal Marker Protein Under The Control Of Mt Promoter In Glass Bottom Dishes, supplied by MatTek, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/pmc09917060-272-24-45?v=MatTek
Average 90 stars, based on 1 article reviews
d.mel-2 cells expressing the mcherry-sas6 centrosomal marker protein under the control of mt promoter in glass bottom dishes - by Bioz Stars, 2026-08
90/100 stars
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d-mel2 cell lines  (National Centre for Cell Science)
90
National Centre for Cell Science d-mel2 cell lines
a) Violin plot showing proximal to distal usage shifts across each class of significant APA event. Proximal to distal usage shift is calculated as: dPA change in usage - pPA change in usage. White square = median. b) Scatter plots displaying Pearson correlation (r) of DMAi-induced poly(A) site usage change between different cell lines. Upper left = LU-99 vs MCF7, Lower left = NCI-H838 vs SUM149PT, Upper right = <t>PANC0403</t> vs GP2D. Lower right = HCT116 p53 +/+ vs U2OS. c) Distribution of proximal poly(A) usage across all genes in a patient-derived lung tumour organoid model versus normal lung tissue organoids derived from the same patient. Scale: 0 = 0% usage, 1 = 100% usage. Statistical significance was calculated using the Kruskal-Wallis Test. d) An example of a 3’ UTR ( Prkca) whose shortening upon T cell activation (blue) is prevented by DMAi (red).
D Mel2 Cell Lines, supplied by National Centre for Cell Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/pm23697686-48-0-6?v=National+Centre+for+Cell+Science
Average 90 stars, based on 1 article reviews
d-mel2 cell lines - by Bioz Stars, 2026-08
90/100 stars
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sk-mel-2 cells containing the luc gene  (JCRB Cell Bank)
90
JCRB Cell Bank sk-mel-2 cells containing the luc gene
a) Violin plot showing proximal to distal usage shifts across each class of significant APA event. Proximal to distal usage shift is calculated as: dPA change in usage - pPA change in usage. White square = median. b) Scatter plots displaying Pearson correlation (r) of DMAi-induced poly(A) site usage change between different cell lines. Upper left = LU-99 vs MCF7, Lower left = NCI-H838 vs SUM149PT, Upper right = <t>PANC0403</t> vs GP2D. Lower right = HCT116 p53 +/+ vs U2OS. c) Distribution of proximal poly(A) usage across all genes in a patient-derived lung tumour organoid model versus normal lung tissue organoids derived from the same patient. Scale: 0 = 0% usage, 1 = 100% usage. Statistical significance was calculated using the Kruskal-Wallis Test. d) An example of a 3’ UTR ( Prkca) whose shortening upon T cell activation (blue) is prevented by DMAi (red).
Sk Mel 2 Cells Containing The Luc Gene, supplied by JCRB Cell Bank, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mel-2/pm35525268-123-4-6?v=JCRB+Cell+Bank
Average 90 stars, based on 1 article reviews
sk-mel-2 cells containing the luc gene - by Bioz Stars, 2026-08
90/100 stars
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Image Search Results


a) Violin plot showing proximal to distal usage shifts across each class of significant APA event. Proximal to distal usage shift is calculated as: dPA change in usage - pPA change in usage. White square = median. b) Scatter plots displaying Pearson correlation (r) of DMAi-induced poly(A) site usage change between different cell lines. Upper left = LU-99 vs MCF7, Lower left = NCI-H838 vs SUM149PT, Upper right = PANC0403 vs GP2D. Lower right = HCT116 p53 +/+ vs U2OS. c) Distribution of proximal poly(A) usage across all genes in a patient-derived lung tumour organoid model versus normal lung tissue organoids derived from the same patient. Scale: 0 = 0% usage, 1 = 100% usage. Statistical significance was calculated using the Kruskal-Wallis Test. d) An example of a 3’ UTR ( Prkca) whose shortening upon T cell activation (blue) is prevented by DMAi (red).

Journal: bioRxiv

Article Title: PRMT activity promotes global 3’ UTR shortening in proliferating cells

doi: 10.1101/2025.03.06.641848

Figure Lengend Snippet: a) Violin plot showing proximal to distal usage shifts across each class of significant APA event. Proximal to distal usage shift is calculated as: dPA change in usage - pPA change in usage. White square = median. b) Scatter plots displaying Pearson correlation (r) of DMAi-induced poly(A) site usage change between different cell lines. Upper left = LU-99 vs MCF7, Lower left = NCI-H838 vs SUM149PT, Upper right = PANC0403 vs GP2D. Lower right = HCT116 p53 +/+ vs U2OS. c) Distribution of proximal poly(A) usage across all genes in a patient-derived lung tumour organoid model versus normal lung tissue organoids derived from the same patient. Scale: 0 = 0% usage, 1 = 100% usage. Statistical significance was calculated using the Kruskal-Wallis Test. d) An example of a 3’ UTR ( Prkca) whose shortening upon T cell activation (blue) is prevented by DMAi (red).

Article Snippet: GP2D, NCI-H838, LU-99, PANC0403, SK-MEL-2, SUM149PT and U2OS cells were sourced from the AstraZeneca Global Cell Bank.

Techniques: Derivative Assay, Activation Assay

a) Upper = Scatter plots displaying Pearson correlation (r) in poly(A) site usage change triggered by DMAi versus siPCF11 (left) and CPSF73i (right). Lower = Pearson correlation (r) in poly(A) site usage change triggered by DMAi versus all other APA-inducing perturbation datasets within the 3’ RNA-seq panel. b) Comparison of position-dependent frequency of occurrence of GU-rich motifs within proximal and distal regions at DMAi-lengthened (red), non-DMAi-lengthened (green) and control (grey) sites. Running averages were calculated over 15 consecutive nucleotide positions. GU-rich motif = any 4mer combination of 2Gs + 2Us. c) Comparison of position-dependent frequency of occurrence of GU-rich motifs within proximal and distal regions at DMAi-lengthened (red) and unchanged, control (grey) 3’ UTRs, across three representative cancer lines. Upper = GP2D, Middle = HCT116 p53 +/+, Lower = PANC0403. d) CSTF2 eCLIP binding around poly(A) sites in 3’ UTRs across DMAi-vs non-DMAi-lengthened transcripts (expression matched), calculated from ENCODE consortium data in HepG2 cells. e) Distribution of % GC content within each gene region among DMAi-lengthened (red), non-DMAi-lengthened (green) and control (grey) genes. f) Distribution of baseline proximal poly(A) site usage in control (grey), DMAi-lengthened (red) and non-DMAi-lengthened (green) categories (expression matched). Scale: 0 = 0% usage, 1 = 100% usage. Statistical significance was calculated using the Kruskal-Wallis Test, with Bonferroni method p value adjustment for multiple testing. g) Boxplot showing the nucleotide distance between proximal and distal poly(A) sites at control (grey), DMAi-lengthened (red) and non-DMAi-lengthened (green) sites. Statistical significance was calculated using the Kruskal-Wallis Test, with Bonferroni method p value adjustment for multiple testing.

Journal: bioRxiv

Article Title: PRMT activity promotes global 3’ UTR shortening in proliferating cells

doi: 10.1101/2025.03.06.641848

Figure Lengend Snippet: a) Upper = Scatter plots displaying Pearson correlation (r) in poly(A) site usage change triggered by DMAi versus siPCF11 (left) and CPSF73i (right). Lower = Pearson correlation (r) in poly(A) site usage change triggered by DMAi versus all other APA-inducing perturbation datasets within the 3’ RNA-seq panel. b) Comparison of position-dependent frequency of occurrence of GU-rich motifs within proximal and distal regions at DMAi-lengthened (red), non-DMAi-lengthened (green) and control (grey) sites. Running averages were calculated over 15 consecutive nucleotide positions. GU-rich motif = any 4mer combination of 2Gs + 2Us. c) Comparison of position-dependent frequency of occurrence of GU-rich motifs within proximal and distal regions at DMAi-lengthened (red) and unchanged, control (grey) 3’ UTRs, across three representative cancer lines. Upper = GP2D, Middle = HCT116 p53 +/+, Lower = PANC0403. d) CSTF2 eCLIP binding around poly(A) sites in 3’ UTRs across DMAi-vs non-DMAi-lengthened transcripts (expression matched), calculated from ENCODE consortium data in HepG2 cells. e) Distribution of % GC content within each gene region among DMAi-lengthened (red), non-DMAi-lengthened (green) and control (grey) genes. f) Distribution of baseline proximal poly(A) site usage in control (grey), DMAi-lengthened (red) and non-DMAi-lengthened (green) categories (expression matched). Scale: 0 = 0% usage, 1 = 100% usage. Statistical significance was calculated using the Kruskal-Wallis Test, with Bonferroni method p value adjustment for multiple testing. g) Boxplot showing the nucleotide distance between proximal and distal poly(A) sites at control (grey), DMAi-lengthened (red) and non-DMAi-lengthened (green) sites. Statistical significance was calculated using the Kruskal-Wallis Test, with Bonferroni method p value adjustment for multiple testing.

Article Snippet: GP2D, NCI-H838, LU-99, PANC0403, SK-MEL-2, SUM149PT and U2OS cells were sourced from the AstraZeneca Global Cell Bank.

Techniques: RNA Sequencing, Comparison, Control, Binding Assay, Expressing